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  • Clinical Significance of C-reactive Protein

    Edición de Waliza Ansar, Shyamasree Ghosh ...
    Series series Biomedical and Life Sciences (R0)
    This book explores the latest developments in the field the acute phase protein (APP), C-reactive protein or CRP in different diseases, highlighting the structural and functional aspects of CRP in disease biology.Divided into 5 sections, the book examines important topics such as the role of CRP in neurodegenerative, cardiac and parasitic diseases, as well as in cancer and inflammatory bowel ... Leer más

    $188.99 USD

  • Biology of C Reactive Protein in Health and Disease

    Series series Biomedical and Life Sciences (R0)
    This book offers a comprehensive study of C-reactive protein (CRP) belonging to the pentraxin family, including a brief history of CRP, its structure, synthesis and evolution. Focusing on the emerging role of CRP and its clinical application in the field of disease biology, it details the pathophysiological role of CRP in a host of diseases such as cardiovascular disease, diabetes, cancers, ... Leer más

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  • microRNA: Medical Evidence

    From Molecular Biology to Clinical Practice

    Edición de Gaetano Santulli ...
    Series series Biomedical and Life Sciences (R0)
    This volume explores microRNA function in a wide array of human disorders, providing a clinical basis for precision medicine and personalized therapies using these molecules. The twenty-one chapters, all authored by internationally-renowned experts, open with an introduction contextualizing microRNA manipulation within today’s initiatives towards precision medicine. The following chapters explore ... Leer más

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  • Uncultivated Microorganisms

    Edición de Slava S. Epstein ...
    Series series Biomedical and Life Sciences (R0)
    In 1898, an Austrian microbiologist Heinrich Winterberg made a curious observation: the number of microbial cells in his samples did not match the number of colonies formed on nutrient media (Winterberg 1898). About a decade later, J. Amann qu- tified this mismatch, which turned out to be surprisingly large, with non-growing cells outnumbering the cultivable ones almost 150 times (Amann 1911). ... Leer más

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  • Platelets in Thrombotic and Non-Thrombotic Disorders

    Pathophysiology, Pharmacology and Therapeutics: an Update

    Series series Biomedical and Life Sciences (R0)
    This book reviews current science and applications in fields including thrombosis and hemostasis, signal transduction, and non-thrombotic conditions such as inflammation, allergy and tumor metastasis. It is a detailed, up-to-date, highly referenced text for clinical scientists and physicians, including recent developments in this rapidly expanding field. More than a scientific resource, this is ... Leer más

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  • Arterial Stiffness

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    Series series Biomedical and Life Sciences (R0)
    Arterial stiffness is an emerging risk factor with important implications for cardiovascular disease risk. Herein, we concisely summarize the physiological and pathophysiological aspects of arterial stiffening, and highlight the importance of increased arterial stiffness for future cardiovascular events. Factors contributing to increased arterial stiffness such as advancing age, obesity, race, sex ... Leer más

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  • microRNA: Basic Science

    From Molecular Biology to Clinical Practice

    Edición de Gaetano Santulli ...
    Series series Biomedical and Life Sciences (R0)
    This volume explores microRNA pathophysiology, focusing on basic concepts in molecular and cellular biology. Chapters contributed by leading scientists examine recently discovered pathways in several processes, including aging, diabetes, cardiovascular disease, hematopoiesis, and mitochondrial fitness. The authors contextualize microRNAs within epigenetics and micropeptidomics, angiongenesis and ... Leer más

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  • Proteinuria: Basic Mechanisms, Pathophysiology and Clinical Relevance

    Edición de Judith Blaine ...
    Series series Biomedical and Life Sciences (R0)
    Recent work has begun to elucidate at the molecular level how albumin is handled by the kidney and how albuminuria develops in various proteinuric diseases including minimal change disease and focal segmental glomerulosclerosis. This volume provides a comprehensive overview of the renal handling of albumin – from basic mechanisms to the pathophysiology of proteinuric diseases. In describing the ... Leer más

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  • Molecular and Cellular Mechanobiology

    Series series Biomedical and Life Sciences (R0)
    This book will cover the cutting-edge developments in molecular and cellular mechanobiology to date. Readers will have a clear understanding of mechanobiology at the molecular and cellular levels, encompassing the mechanosensors, transducers, and transcription. An integrative approach across different scales from molecular sensing to mechanotransduction and gene modulation for physiological ... Leer más

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  • Molecular mechanisms and physiology of disease

    Implications for Epigenetics and Health

    Series series Biomedical and Life Sciences (R0)
    In a simplified form, epigenetics refers to heritable changes in phenotype that are not due to changes in the underlying DNA sequence. In this book, epigenetic mechanisms of regulation and dysregulation in health and disease are explored in great depth. Detailed chapters on epigenetic processes including DNA methylation and chromatin post-translational modifications including potential ... Leer más

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  • Exosomes in Cardiovascular Diseases

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    Edición de Junjie Xiao, Sanda Cretoiu ...
    Series series Biomedical and Life Sciences (R0)
    The book provides and intensive overview on exosomes in cardiovascular diseases, its potential as biomarkers, as well as pathological and therapeutic effects. It firstly describes the general aspects of exosomes including the definition, formation and secretion of exosomes and highlight their roles as biomarkers and pathological and therapeutic effects in cardiovascular diseases as well. Secondly, ... Leer más

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  • Long Circulating Liposomes: Old Drugs, New Therapeutics

    Edición de Martin C. Woodle, Gerrit Storm ...
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    This book provides an up-to-date evaluation of clinical aspects of newly available "long-circulating liposome" formulations. Based on results from numerous clinical studies, the book describes the fundamentals of this new technology, discusses how it may influence the pharmacology of existing well-known agents reformulated in this manner, and elaborates on future expectations. It provides the ... Leer más

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