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  • Clinical Applications of Noncoding RNAs in Cancer

    Clinical Applications of Noncoding RNAs in Cancer summarizes the existing strategies, advances, and future opportunities on the role of noncoding RNAs in cancer patients. Established clinicians and researchers from all around the world share their views and expertise and provide readers with invaluable knowledge on the subject. This book provides a comprehensive collection of information on the ... Leer más

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  • Translational Research in Breast Cancer

    Series series Biomedical and Life Sciences (R0)
    This book describes recent advances in translational research in breast cancer and presents emerging applications of this research that promise to have meaningful impacts on diagnosis and treatment. It introduces ideas and materials derived from the clinic that have been brought to "the bench" for basic research, as well as findings that have been applied back to "the bedside". Detailed attention ... Leer más

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  • MicroRNA in Human Malignancies

    MicroRNA in Human Malignancies offers a deep overview of the role and translational significance of miRNAs in the development of cancer and other malignancies. The book establishes the foundations of the field by covering essential mechanisms and the translational potential of miRNAs in the field of oncology. Specific topics covered include invasion and metastasis, miRNAs and metabolism, and ... Leer más

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  • MicroRNAs: Key Regulators of Oncogenesis

    Edición de Sadegh Babashah ...
    Series series Biomedical and Life Sciences (R0)
    Aberrant expression and function of microRNAs (miRNAs) in cancer have added a new layer of complexity to the understanding of development and progression of the disease state. It has been demonstrated that miRNAs have a crucial function in oncogenesis by regulating cell proliferation and apoptosis as oncogenes or tumor suppressors. The expression signatures of miRNAs provide exciting opportunities ... Leer más

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  • Non-coding RNAs in Colorectal Cancer

    Edición de Ondrej Slaby, George A. Calin ...
    Series series Biomedical and Life Sciences (R0)
    This is the first book to provide a broad framework for obtaining an in depth understanding of the state-of-the-art knowledge on abnormalities of non-coding RNAs found to be associated with colorectal cancer pathogenesis. Readers will discover possible mechanisms underlying the substantial roles played by non-coding RNAs in molecular hallmarks of colorectal cancer.This work further provides the ... Leer más

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  • MicroRNA Targeted Cancer Therapy

    Edición de Fazlul H. Sarkar ...
    Series series Biomedical and Life Sciences (R0)
    Since the discovery of microRNAs (miRNAs) some twenty years ago by Victor Ambros, David Baulcombe and Gary Ruvkun, these three scientists worked to uncover the mystery of miRNA, the small segments of nucleotides that silence genes. While studying the development of the nematode worm, Ambros and Ruvkun discovered miRNA in animals, while Baulcombe discovered it in plants. Since their discovery, it ... Leer más

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  • Cancer Stem Cell Markers and Related Network Pathways

    Edición de Shihori Tanabe ...
    Series series Biomedical and Life Sciences (R0)
    This book entitled “Cancer Stem Cell Markers and Related Network Path-ways” is about cancer stem cell (CSC) markers and the molecular network pathways. CSCs play an important role in the cancer drug resistance, metastasis and recurrence. Epithelial-mesenchymal transition (EMT) is closely related to CSC phenotype.This book covers various aspects of the molecular networks related to CSCs including ... Leer más

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  • Cancer Stem Cells: Basic Concept and Therapeutic Implications

    Edición de Farhadul Islam, Alfred K. Lam ...
    Series series Biomedical and Life Sciences (R0)
    This book comprehensively reviews the role of cancer stem cells (CSCs) in cancer initiation, progression, and resistance to anticancer therapies. The initial chapters examine the methods and procedure of the detection, isolation, and characterization of CSCs. It also introduces various epigenetic pathways that contribute to cancer initiation and tumorigenesis, particularly regarding the ... Leer más

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  • Cancer Cell Chemoresistance And Chemosensitization

    Despite the significant advances in cancer therapy made through constant evaluation and analysis of treatment aftereffects, the disease still remains one of the foremost causes of mortality worldwide killing more than 12 million people annually. The prime reason behind the failure of conventional chemotherapeutics which are used as the chief regimen in the comprehensive treatment of cancers is the ... Leer más

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  • Noncoding RNAs and Bone

    Edición de Airong Qian, Ye Tian ...
    The book provides an in-depth and comprehensive overview of the essential role of non-coding RNAs (ncRNAs) in bone formation. In combination with researches from multiple scholars in this field, the book reviews the mechanisms of ncRNA-related bone diseases, as well as the potential applications of RNA synthesis technology in bone disorder treatments. This volume covers the following topics: 1) ... Leer más

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  • Autophagy in tumor and tumor microenvironment

    Edición de Sujit Kumar Bhutia ...
    Series series Biomedical and Life Sciences (R0)
    This book deals with the paradoxical role of autophagy in tumor suppression and tumor promotion in cancer cells. Autophagy plays opposing, context-dependent roles in tumors; accordingly, strategies based on inhibiting or stimulating autophagy could offer as potential cancer therapies.The book elucidates the physiological role of autophagy in modulating cancer metastasis, which is the primary cause ... Leer más

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  • YY1 in the Control of the Pathogenesis and Drug Resistance of Cancer

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    Edición de Benjamin Bonavida ...
    YY1 Is Pivotal in the Control of the Pathogenesis and Drug Resistance of Cancer: A Critical Therapeutic Target describes the current state-of-the-art of the transcription factor YY1 that is overexpressed in the majority of cancers and a central factor that regulates all of the major features and characteristics of human cancers. This book emphasizes the biochemical, molecular and genetic ... Leer más

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