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  • Biosimilar Clinical Development: Scientific Considerations and New Methodologies

    Series series Chapman & Hall/CRC Biostatistics Series
    Biosimilars have the potential to change the way we think about, identify, and manage health problems. They are already impacting both clinical research and patient care, and this impact will only grow as our understanding and technologies improve. Written by a team of experienced specialists in clinical development, this book discusses various potential drug development strategies, the design and ... Leer más

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  • Statistical Bioinformatics with R

    Statistical Bioinformatics provides a balanced treatment of statistical theory in the context of bioinformatics applications. Designed for a one or two semester senior undergraduate or graduate bioinformatics course, the text takes a broad view of the subject – not just gene expression and sequence analysis, but a careful balance of statistical theory in the context of bioinformatics applications. ... Leer más

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  • Epidemiology and Medical Statistics

    Series Libro 27 - Handbook of Statistics
    This volume, representing a compilation of authoritative reviews on a multitude of uses of statistics in epidemiology and medical statistics written by internationally renowned experts, is addressed to statisticians working in biomedical and epidemiological fields who use statistical and quantitative methods in their work. While the use of statistics in these fields has a long and rich history, ... Leer más

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  • Advances in Statistical Bioinformatics

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    Providing genome-informed personalized treatment is a goal of modern medicine. Identifying new translational targets in nucleic acid characterizations is an important step toward that goal. The information tsunami produced by such genome-scale investigations is stimulating parallel developments in statistical methodology and inference, analytical frameworks, and computational tools. Within the ... Leer más

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  • Advanced Medical Statistics (2nd Edition)

    The book aims to provide both comprehensive reviews of the classical methods and an introduction to new developments in medical statistics. The topics range from meta analysis, clinical trial design, causal inference, personalized medicine to machine learning and next generation sequence analysis. Since the publication of the first edition, there have been tremendous advances in biostatistics and ... Leer más

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  • Statistical Analysis of Microbiome Data with R

    Series series Mathematics and Statistics (R0)
    This unique book addresses the statistical modelling and analysis of microbiome data using cutting-edge R software. It includes real-world data from the authors’ research and from the public domain, and discusses the implementation of R for data analysis step by step. The data and R computer programs are publicly available, allowing readers to replicate the model development and data analysis ... Leer más

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  • Statistics and Informatics in Molecular Cancer Research

    Edición de Carsten Wiuf, Claus L. Andersen ...
    Molecular understanding of cancer and cancer progression is at the forefront of many research programs today. High-throughput array technologies and other modern molecular techniques produce a wealth of molecular data about the structure, and function of cells, tissues, and organisms. Correctly analyzed and interpreted these data hold the promise of bringing new markers for prognostic and ... Leer más

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  • Bioinformatics in Human Health and Heredity

    Series Libro 28 - Handbook of Statistics
    The field of statistics not only affects all areas of scientific activity, but also many other matters such as public policy. It is branching rapidly into so many different subjects that a series of handbooks is the only way of comprehensively presenting the various aspects of statistical methodology, applications, and recent developments. The Handbook of Statistics, a series of self-contained ... Leer más

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  • Statistical Bioinformatics

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    de Jae K. Lee ...
    This book provides an essential understanding of statistical concepts necessary for the analysis of genomic and proteomic data using computational techniques. The author presents both basic and advanced topics, focusing on those that are relevant to the computational analysis of large data sets in biology. Chapters begin with a description of a statistical concept and a current example from ... Leer más

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  • Sample Size Calculations in Clinical Research

    Series series Chapman & Hall/CRC Biostatistics Series
    Praise for the Second Edition:"… this is a useful, comprehensive compendium of almost every possible sample size formula. The strong organization and carefully defined formulae will aid any researcher designing a study." -Biometrics"This impressive book contains formulae for computing sample size in a wide range of settings. One-sample studies and two-sample comparisons for quantitative, binary, ... Leer más

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  • Statistical Genomics

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    Genomics, the mapping of the entire genetic complement of an organism, is the new frontier in biology. This handbook on the statistical issues of genomics covers current methods and the tried-and-true classical approaches. ... Leer más

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  • Innovative Strategies, Statistical Solutions and Simulations for Modern Clinical Trials

    Series series Chapman & Hall/CRC Biostatistics Series
    "This is truly an outstanding book. [It] brings together all of the latest research in clinical trials methodology and how it can be applied to drug development…. Chang et al provide applications to industry-supported trials. This will allow statisticians in the industry community to take these methods seriously." Jay Herson, Johns Hopkins UniversityThe pharmaceutical industry's approach to drug ... Leer más

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