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“roy jefferis”

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  • Introduction to Biological and Small Molecule Drug Research and Development

    Theory and Case Studies

    Edición de Stanley M. Roberts, C. Robin Ganellin, Roy Jefferis ...
    Introduction to Biological and Small Molecule Drug Research and Development provides, for the first time, an introduction to the science behind successful pharmaceutical research and development programs. The book explains basic principles, then compares and contrasts approaches to both biopharmaceuticals (proteins) and small molecule drugs, presenting an overview of the business and management ... Leer más

    $80.99 USD

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  • Drug-Like Properties

    Concepts, Structure Design and Methods from ADME to Toxicity Optimization

    de Li Di, Edward H Kerns ...
    Of the thousands of novel compounds that a drug discovery project team invents and that bind to the therapeutic target, only a fraction have sufficient ADME (absorption, distribution, metabolism, elimination) properties, and acceptable toxicology properties, to become a drug product that will successfully complete human Phase I clinical trials. Drug-Like Properties: Concepts, Structure Design and ... Leer más

    $179.99 USD

  • Specification of Drug Substances and Products

    Development and Validation of Analytical Methods

    Edición de Thomas W. Rosanske, Christopher M. Riley ...
    Specification of Drug Substances and Products: Development and Validation of Analytical Methods is a comprehensive and critical analysis of the requirements and approaches to setting specifications for new pharmaceutical products, with an emphasis on phase-appropriate development and validation of analytical methods. This book is intended as more than a review of new regional guidelines, existing ... Leer más

    $107.99 USD

  • Evidence-Based Validation of Herbal Medicine

    Edición de Pulok K. Mukherjee ...
    Evidence-Based Validation of Herbal Medicines brings together current thinking and practice in the areas of characterization and validation of natural products. This book reviews all aspects of evaluation and development of medicines from plant sources, including their cultivation, collection, phytochemical and phyto-pharmacological evaluation, and therapeutic potential. Emphasis is placed on ... Leer más

    $202.99 USD

  • Privileged Structures in Drug Discovery

    Medicinal Chemistry and Synthesis

    de Larry Yet ...
    A comprehensive guide to privileged structures and their application in the discovery of new drugsThe use of privileged structures is a viable strategy in the discovery of new medicines at the lead optimization stages of the drug discovery process. Privileged Structures in Drug Discovery offers a comprehensive text that reviews privileged structures from the point of view of medicinal chemistry ... Leer más

    $174.00 USD

  • Advances in Organometallic Chemistry

    de Anthony F. Hill, Robert C. West ...
    Series Libro 43 - Advances in Organometallic Chemistry
    This book is an essential reference work for the academic and industrial chemists and will provide up-to-date material at the cutting edge of chemistry research.This widely-acclaimed serial contains authoritative reviews that address all aspects of organometallic chemistry, a field which has expanded enormously since the publication of Volume 1 in 1964. Almost all branches of chemistry and ... Leer más

    $202.99 USD

  • Meyler's Side Effects of Drugs 15E

    The International Encyclopedia of Adverse Drug Reactions and Interactions

    Edición de Jeffrey K. Aronson, MA DPhil MBChB FRCP FBPharmacolS FFPM(Hon) ...
    Building on the success of the 14 previous editions, this remarkable reference has been extensively reorganized and expanded and now comprises almost 1,500 individual drug articles providing the most complete coverage of adverse reactions and interactions found anywhere. Each article contains detailed and authoritative information about the adverse effects of each drug, with comprehensive ... Leer más

    $2,429.99 USD

  • Prodrug Design

    Perspectives, Approaches and Applications in Medicinal Chemistry

    de Vivekkumar K Redasani, Sanjay B. Bari ...
    Prodrug Design: Perspectives, Approaches and Applications in Medicinal Chemistry provides a focused overview of this critical area of drug discovery, as that continuous process strives not only to discover new drug compounds but also to modify the existing ones. This valuable primer supports this mission of drug development and its goal of reducing undesired effects and improving therapeutic ... Leer más

    $44.99 USD

  • Significant Pharmaceuticals Reported in US Patents

    de Thomas F. DeRosa ...
    Significant Pharmaceuticals Reported in US Patents identifies the next generation of pharmaceuticals reported in US Patents. This "hands-on" title provides explicit laboratory methods for preparing the most recent and effective medications. Each entry documents the biological testing protocols used to evaluate a drug and the significance of the current treatment agent over previous methods. ... Leer más

    $206.99 USD

  • Analytical Profiles of Drug Substances and Excipients

    de Harry G. Brittain ...
    Series Libro 25 - Analytical Profiles of Drug Substances and Excipients
    Although the official compendia define a drug substance as to identity, purity, strength, and quality, they normally do not provide other physical or chemical data, nor do they list methods of synthesis or pathways of physical or biological degradation and metabolism. Such information is scattered throughout the scientific literature and the files of pharmaceutical laboratories. Edited by the ... Leer más

    $224.99 USD

  • Signposts to Chiral Drugs

    Organic Synthesis in Action

    de Vitomir Sunjic, Michael Parnham ...
    Series series Biomedical and Life Sciences (R0)
    Highlighting 15 selected chiral structures, which represent candidate or marketed drugs, and their chemical syntheses, the authors acquaint the reader with the fascinating achievements of synthetic and medicinal chemistry.The book starts with an introduction treating the discovery and development of a new drug entity. Each of the 15 subsequent chapters presents one of the target structures and ... Leer más

    $143.99 USD

  • Design of Hybrid Molecules for Drug Development

    Edición de Michael Decker ...
    Design of Hybrid Molecules for Drug Development reviews the principles, advantages, and limitations involved with designing these groundbreaking compounds. Beginning with an introduction to hybrid molecule design and background as to their need, the book goes on to explore a range of important hybrids, with hybrids containing natural products, molecules containing NO- and H2S-donors, dual-acting ... Leer más

    $188.99 USD