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  • Circulating Tumor Cells

    Edición de Richard J. Cote, Ram Datar ...
    Series series Medicine (R0)
    This volume provides the latest research on circulating tumor cells aimed for cancer researchers, scientists, and molecular oncologists. It presents the basic concepts behind circulating tumor cells (CTCs), metastatic biology, and potential applications as to how CTCs can be used in diagnostic biomarkers.CTCs are cells that have detached from the primary tumor and circulate in the bloodstream. ... Leer más

    $143.99 USD

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  • Platelet Proteomics

    Principles, Analysis, and Applications

    Series Libro 47 - Wiley Series on Mass Spectrometry
    The purpose of the book is to introduce platelets, and their functional role in thrombotic and cardiovascular disease, justifying the relevance of platelet proteomics research. Focus then shifts to the recent developments on mass spectrometry (MS)-based proteomics. This chapter shows potential applications for platelet proteomics not yet carried out. It includes examples of post-translational ... Leer más

    $107.00 USD

  • Tumor Microenvironment

    Edición de Dietmar W. Siemann ...
    The microenvironment in which a tumor originates plays a critical role in its initiation and progression. Tumor Microenvironment reviews the importance of tumor microenvironment in cancer management. Particular emphasis is placed on discussing how the unique characteristics of the tumor microenvironment not only impact disease progression and response to conventional anticancer therapies, but have ... Leer más

    $148.00 USD

  • Recombinant Antibodies for Immunotherapy

    Edición de Melvyn Little, PhD ...
    Recombinant Antibodies for Immunotherapy provides a comprehensive overview of the field of monoclonal antibodies (mAbs), a market that has grown tremendously in recent years. Twenty-five articles by experienced and innovative authors cover the isolation of specific human mAbs, humanization, immunogenicity, technologies for improving efficacy, 'arming' mAbs, novel alternative Ab constructs, ... Leer más

    $104.99 USD

  • Polypharmacology in Drug Discovery

    Edición de Jens-Uwe Peters ...
    An essential outline of the main facets of polypharmacology in drug discovery researchExtending drug discovery opportunities beyond the "one drug, one target" philosophy, a polypharmacological approach to the treatment of complex diseases is emerging as a hot topic in both industry and academic research. Polypharmacology in Drug Discovery presents an overview of the various facets of ... Leer más

    $127.00 USD

  • Analogue-based Drug Discovery II

    Born out of a project of the IUPAC's committee on Medicinal Chemistry and Drug Development, this reference addresses past and current strategies for successful drug analog development, extending the previously published volume by nine new analog classes and eight case studies. Like its precursor, this volume also contains a general section discussing universally applicable strategies for analog ... Leer más

    $212.00 USD

  • Therapeutic Monoclonal Antibodies

    From Bench to Clinic

    Edición de Zhiqiang An ...
    70-chapter authoritative reference that covers therapeutic monoclonal antibody discovery, development, and clinical applications while incorporating principles, experimental data, and methodologies.First book to address the discovery and development of antibody therapeutics in their entirety.Most chapters contain experimental data to illustrate the principles described in them.Authors provide ... Leer más

    $198.00 USD

  • Innovations for Next-Generation Antibody-Drug Conjugates

    Edición de Marc Damelin ...
    Series series Medicine (R0)
    Antibody-drug conjugates (ADCs) stand at the verge of a transformation. Scores of clinical programs have yielded only a few regulatory approvals, but a wave of technological innovation now empowers us to overcome past technical challenges. This volume focuses on the next generation of ADCs and the innovations that will enable them. The book inspires the future by integrating the field’s history ... Leer más

    $143.09 USD

  • Fusion Protein Technologies for Biopharmaceuticals

    Applications and Challenges

    Edición de Stefan R. Schmidt ...
    The state of the art in biopharmaceutical FUSION PROTEIN DESIGNFusion proteins belong to the most lucrative biotech drugs-with Enbrel® being one of the best-selling biologics worldwide. Enbrel® represents a milestone of modern therapies just as Humulin®, the first therapeutic recombinant protein for human use, approved by the FDA in 1982 and Orthoclone® the first monoclonal antibody reaching the ... Leer más

    $191.00 USD

  • Antibody-Drug Conjugates

    The 21st Century Magic Bullets for Cancer

    Series series Biomedical and Life Sciences (R0)
    This authoritative volume provides a holistic picture of antibody-drug conjugates (ADCs). Fourteen comprehensive chapters are divided into six sections including an introduction to ADCs, the ADC construct, development issues, landscape, IP and pharmacoeconomics, case studies, and the future of the field. The book examines everything from the selection of the antibody, the drug, and the linker to a ... Leer más

    $98.99 USD

  • Antibody Drug Discovery

    de Clive R Wood ...
    Series Libro 4 - Molecular Medicine And Medicinal Chemistry
    Monoclonal antibodies have become important treatments for cancer, inflammation and a wide range of other diseases, representing an increasing share of the most successful pharmaceutical markets. The technologies to discover these drugs have been developed by select centers of excellence in industry and academia, and are continually being fine tuned in the race to identify the best antibody-based ... Leer más

    $56.99 USD

  • Therapeutic Antibody Engineering

    Current and Future Advances Driving the Strongest Growth Area in the Pharmaceutical Industry

    Series series Woodhead Publishing Series in Biomedicine
    The field of antibody engineering has become a vital and integral part of making new, improved next generation therapeutic monoclonal antibodies, of which there are currently more than 300 in clinical trials across several therapeutic areas. Therapeutic antibody engineering examines all aspects of engineering monoclonal antibodies and analyses the effect that various genetic engineering approaches ... Leer más

    $269.99 USD