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1 - 12 de 12 resultados para “peter j sadler”
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  • Metallopharmaceuticals I

    DNA Interactions

    Edición de Michael J. Clarke, Peter J. Sadler ...
    Series series Biomedical and Life Sciences (R0)
    Biological inorganic chemistry is a field of research at the interface of inorganic and biological chemistry. The rapidly developing insights into the role of metals in biological systems has far-reaching implications not only for biological science but also for related disciplines, ranging from molecular medicine to the environment. In each volume the reader, whether engaged in chemistry, ... Leer más

    $188.99 USD

  • Medicinal Chemistry

    de Rudi van Eldik, Peter J. Sadler ...
    Series Libro 75 - Advances in Inorganic Chemistry
    Medicinal Chemistry, Volume 75, the latest release in the Advances in Inorganic Chemistry series, presents timely and informative summaries on current progress in a variety of subject areas. This acclaimed serial features reviews written by experts in the field, serving as an indispensable reference to advanced researchers that empowers readers to pursue new developments in each field. Users will ... Leer más

    $246.99 USD

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  • Platelets in Thrombotic and Non-Thrombotic Disorders

    Pathophysiology, Pharmacology and Therapeutics: an Update

    Edición de Paolo Gresele, Neal S. Kleiman, José A. Lopez, Clive P. Page ...
    Series series Biomedical and Life Sciences (R0)
    This book reviews current science and applications in fields including thrombosis and hemostasis, signal transduction, and non-thrombotic conditions such as inflammation, allergy and tumor metastasis. It is a detailed, up-to-date, highly referenced text for clinical scientists and physicians, including recent developments in this rapidly expanding field. More than a scientific resource, this is ... Leer más

    $332.99 USD

  • Anticancer Genes

    Edición de Stefan Grimm ...
    Series series Biomedical and Life Sciences (R0)
    This book discusses the emergence of a new class of genes with a specific anticancer activity. These genes, recently defined as “Anticancer Genes”, are reviewed in individual chapters on their mode of action, the specific cell death signals they induce, and the status of attempts to translate them into clinical application.Anticancer Genes provides an overview of this nascent field, its genesis, ... Leer más

    $89.99 USD

  • High Throughput Screening for Novel Anti-Inflammatories

    Edición de Michael Kahn ...
    Series series Progress in Inflammation Research
    Combinatorial chemistry in conjunction with High Throughput Screening (HTS) is revolutionizing the drug discovery process. Yet, we have much to learn about the integration of these powerful techniques with information from genomics, proteomics, computation and pharmacokinetics before dramatic increases in the drug discovery/development processes can be achieved. The chapters in this book represent ... Leer más

    $143.99 USD

  • Rabies in Man and Animals

    de Sudhi Ranjan Garg ...
    Rabies is the deadliest zoonotic disease that threatens humans and animals on all continents except Antarctica. Asia and Africa are worst affected as more than 95 per cent of rabies associated human deaths occur in these regions. India alone bears about 36 per cent of the global human rabies burden. Dogs are the main transmitters of rabies that potentially threaten over 3 billion people in Asia ... Leer más

    $143.99 USD

  • Antitumor Potential and other Emerging Medicinal Properties of Natural Compounds

    Edición de Evandro Fei Fang, Tzi Bun Ng ...
    Series series Biomedical and Life Sciences (R0)
    The modern unhealthy diet and lifestyle in conjunction with pathogens, environmental carcinogens and multiple other risk factors increase humans’ susceptibility to different diseases exemplified by elevated levels of cancers, cardiovascular and communicable diseases. Screening of potential drugs from medicinal plants and animals provides a promising strategy for the alleviation of the impact of ... Leer más

    $143.99 USD

  • Safety and Efficacy of Gene-Based Therapeutics for Inherited Disorders

    Edición de Nicola Brunetti-Pierri ...
    Series series Biomedical and Life Sciences (R0)
    In this book, leading international experts analyze state-of-the-art advances in gene transfer vectors for applications in inherited disorders and also examine the toxicity profiles of these methods. The authors discuss the strengths and weaknesses of available vectors in the clinical setting, and specifically focus on the challenges and possible solutions that researchers are testing in order to ... Leer más

    $143.99 USD

  • Tissue-Specific Estrogen Action

    Novel Mechanisms, Novel Ligands, Novel Therapies

    Edición de Kenneth S. Korach, Tim Wintermantel ...
    Series series Springer Nature Proceedings excluding Computer Science
    Nuclear hormone receptors are not only important drug targets, but have also been the focus of decades of active and highly insightful research. Ten years ago, a review on nuclear receptors was entitled “The Second Decade” and a special issue of Molecular Endocrinology in 2005 dealt with the results of these research efforts. The consensus from nuclear receptor research was of course that the ... Leer más

    $143.09 USD

  • Anti-Cancer N-Heterocyclic Carbene Complexes of Gold(III), Gold(I) and Platinum(II)

    Thiol “Switch-on” Fluorescent Probes, Thioredoxin Reductase Inhibitors and Endoplasmic Reticulum Targeting Agents

    de Taotao Zou ...
    Series series Chemistry and Material Science (R0)
    This thesis focuses on the development of gold- and non-classical platinum-based anti-cancer agents that display distinctively different anti-cancer mechanisms compared to the commonly used cisplatin. These metal complexes contain N-heterocyclic carbene (NHC) ligands which are able to form strong M-C(NHC) bonds, conferring high stability and favorable lipophilicity, reactivity and binding ... Leer más

    $89.99 USD

  • Resistance to Proteasome Inhibitors in Cancer

    Molecular Mechanisms and Strategies to Overcome Resistance

    Edición de Q. Ping Dou ...
    Series series Biomedical and Life Sciences (R0)
    The book explores cutting-edge strategies to overcome proteasome inhibitor resistance, including the second generation 20S proteasome inhibitors, novel combinational therapies, and new targets in the ubiquitin-proteasome pathway (e.g., ubiquitin E3 ligases, deubiquitinases, 19S proteasomal ATPases, histone deacetylases, oxidative stress and proteotoxic stress pathways and pharmacogenomic signature ... Leer más

    $143.99 USD

  • Recent Advances in Glucocorticoid Receptor Action

    Edición de A. Cato, H. Schaecke, K. Asadullah ...
    Series series Medicine (R0)

    $143.99 USD