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  • Decision Making in a World of Comparative Effectiveness Research

    A Practical Guide

    Series series Medicine (R0)
    In the past decade there has been a worldwide evolution in evidence-based medicine that focuses on real-world Comparative Effectiveness Research (CER) to compare the effects of one medical treatment versus another in real world settings. While most of this burgeoning literature has focused on research findings, data and methods, Howard Birnbaum and Paul Greenberg (both of Analysis Group) have ... Leer más

    $89.99 USD

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  • Quantitative Decisions in Drug Development

    Series series Mathematics and Statistics (R0)
    This book offers a high-level treatise of evidence-based decisions in drug development. Because of the inseparable relationship between designs and decisions, a good portion of this book is devoted to the design of clinical trials. The book begins with an overview of product development and regulatory approval pathways. It then discusses how to incorporate prior knowledge into study design and ... Leer más

    $62.99 USD

  • Group Sequential and Confirmatory Adaptive Designs in Clinical Trials

    Series series Mathematics and Statistics (R0)
    This book provides an up-to-date review of the general principles of and techniques for confirmatory adaptive designs. Confirmatory adaptive designs are a generalization of group sequential designs. With these designs, interim analyses are performed in order to stop the trial prematurely under control of the Type I error rate. In adaptive designs, it is also permissible to perform a data-driven ... Leer más

    $134.99 USD

  • Nonclinical Statistics for Pharmaceutical and Biotechnology Industries

    Series series Mathematics and Statistics (R0)
    This book serves as a reference text for regulatory, industry and academic statisticians and also a handy manual for entry level Statisticians. Additionally it aims to stimulate academic interest in the field of Nonclinical Statistics and promote this as an important discipline in its own right. This text brings together for the first time in a single volume a comprehensive survey of methods ... Leer más

    $170.99 USD

  • Advanced Drug Delivery

    Provides both fundamentals and new and emerging applicationsAdvanced Drug Delivery brings readers fully up to date with the state of the science, presenting the basics, formulation strategies, and therapeutic applications of advanced drug delivery. The book demonstrates how core concepts of pharmaceutical sciences, chemistry, and molecular biology can be combined and applied in order to spark ... Leer más

    $126.00 USD

  • The Essential Guide to N-of-1 Trials in Health

    Edición de Jane Nikles, Geoffrey Mitchell ...
    Series series Biomedical and Life Sciences (R0)
    N-of-1 trials, a type of individualized randomized controlled trial, are relevant to almost every discipline in medicine and psychology. They can tell the clinician with precision whether a treatment works in that individual, which distinguishes from the information available from most other trial designs. They have the potential to revolutionize the way clinical medicine is practiced.Whether you ... Leer más

    $152.99 USD

  • Phase II Clinical Development of New Drugs

    Series series ICSA Book Series in Statistics
    This book focuses on how to appropriately plan and develop a Phase II program, and how to design Phase II clinical trials and analyze their data. It provides a comprehensive overview of the entire drug development process and highlights key questions that need to be addressed for the successful execution of Phase II, so as to increase its success in Phase III and for drug approval. Lastly it warns ... Leer más

    $107.99 USD

  • Biosimulation in Biomedical Research, Health Care and Drug Development

    Series series Biomedical and Life Sciences (R0)
    Biosimulation is an approach to biomedical research and the treatment of patients in which computer modeling goes hand in hand with experimental and clinical work. Constructed models are used to interpret experimental results and to accumulate information from experiment to experiment.This book explains the concepts used in the modeling of biological phenomena and goes on to present a series of ... Leer más

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  • Statistical Applications for Chemistry, Manufacturing and Controls (CMC) in the Pharmaceutical Industry

    Series series Mathematics and Statistics (R0)
    This book examines statistical techniques that are critically important to Chemistry, Manufacturing, and Control (CMC) activities. Statistical methods are presented with a focus on applications unique to the CMC in the pharmaceutical industry.The target audience consists of statisticians and other scientists who are responsible for performing statistical analyses within a CMC environment. Basic ... Leer más

    $80.99 USD

  • Antibiotic Pharmacokinetic/Pharmacodynamic Considerations in the Critically Ill

    Series series Medicine (R0)
    This book provides unique insights into the issues that drive modified dosing regimens for antibiotics in the critically ill. Leading international authors provide their commentary alongside a summary of existing evidence on how to effectively dose antibiotics.Severe infection frequently necessitates admission to the intensive care unit (ICU). Equally, nosocomial sepsis often complicates the ... Leer más

    $80.09 USD

  • Pharmacologic Therapy of Ocular Disease

    Series series Biomedical and Life Sciences (R0)
    There have been major advancements in the pharmacologic treatment of eye diseases over the past decade. With newly discovered disease targets and novel approaches to deliver therapeutic compounds to the eye, patients are seeing improved outcomes. Not only are there better treatments for diseases where treatments existed, we now have effective therapy for previously untreatable and blinding eye ... Leer más

    $287.99 USD

  • New Diagnostic, Therapeutic and Organizational Strategies for Acute Coronary Syndromes Patients

    Series series Mathematics and Statistics (R0)
    This book collects several contributions, written both by statisticians and medical doctors, which focus on the identification of new diagnostic, therapeutic and organizational strategies in order to improve the occurrence of clinical outcomes for Acute Coronary Syndromes (ACS) patients. The work is structured in two different parts: the first one is focused on cooperative project mainly on ... Leer más

    $89.99 USD