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1 - 12 de 12 resultados para “mark o j olson”
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  • The Nucleolus

    Edición de Mark O. J. Olson ...
    Series series Biomedical and Life Sciences (R0)
    Within the past two decades, extraordinary new functions for the nucleolus have begun to appear, giving the field a new vitality and generating renewed excitement and interest. These new discoveries include both newly-discovered functions and aspects of its conventional role. The Nucleolus is divided into three parts: nucleolar structure and organization, the role of the nucleolus in ribosome ... Leer más

    $188.99 USD

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  • Lentiviral Vectors and Gene Therapy

    de David Escors, Karine Breckpot, Frederick Arce, Grazyna Kochan, Holly Stephenson ...
    Series series Biomedical and Life Sciences (R0)
    Gene therapy was conceived during the early and mid part of the 20th century. At first, it was considered a revolutionary biomedical procedure, which could potentially cure any disease for which the molecular bases were understood. Since then, gene therapy has gone through many stages and has evolved from a nearly unrealistic perspective to a real life application. Clinical efficacy in humans was ... Leer más

    $49.99 USD

  • miRNA Regulation of the Translational Machinery

    Edición de Robert E. Rhoads ...
    Series series Biomedical and Life Sciences (R0)

    $89.99 USD

  • Non-coding RNAs and Cancer

    Edición de Muller Fabbri ...
    Series series Biomedical and Life Sciences (R0)
    The discovery of microRNAs and its role as gene expression regulators in human carcinogenesis represents one of the most important scientific achievements of the last decade. More recently, other non-coding RNAs have been discovered and its implications in cancer are emerging as well, suggesting a broader than anticipated involvement of the non-coding genome in cancer. Moreover, completely new and ... Leer más

    $98.99 USD

  • Cystogenesis

    Edición de Jong Hoon Park, Curie Ahn ...
    Series series Biomedical and Life Sciences (R0)
    Autosomal Dominant Polycystic Kidney Disease (ADPKD) is a highly prevalent hereditary renal disorder in which fluid-filled cysts are appeared in both kidneys. Main causative genes of ADPKD are PKD1 and PKD2, encoding for polycystin-1 (PC1) and polycystin-2 (PC2) respectively. Those proteins are localized on primary cilia and function as mechanosensor in response to the fluid flow, translating ... Leer más

    $89.99 USD

  • Trinucleotide Diseases and Instability

    Edición de Ben A. Oostra ...
    Series series Biomedical and Life Sciences (R0)
    Till recently, mutations in genes were described in textbooks as deletions or point mutations. These mutations can be inherited from a parent or they are de novo alterations. The discovery in 1991 that human disease can be caused by large-scale ex pansion of highly unstable trinucleotide repeats has elucidated a new mutation mechanism, heritable unstable DNA. In the subsequent years more then 10 ... Leer más

    $49.99 USD

  • MicroRNA Interference Technologies

    de Zhiguo Wang ...
    Series series Biomedical and Life Sciences (R0)
    MicroRNAs (miRNAs), endogenous noncoding regulatory mRNAs of around 22-nucleotides long, have rapidly emerged as one of the key governors of the gene expression regulatory program in cells of varying species, with ever-increasing implications in the control of the fundamental biological processes and in the pathogenesis of adult humans. The exciting findings in this field have inspired us with a ... Leer más

    $143.99 USD

  • Nucleic Acid Nanotechnology

    Edición de Elena Ferapontova, Kurt V. Gothelf, Jørgen Kjems ...
    Series series Biomedical and Life Sciences (R0)
    This volume on nucleic acid nanotechnology offers authoritative, up-to-date and comprehensive coverage of nanotechnological studies and applications of nucleic acids. It provides reviews of various aspects of nucleic acid nanotechnology, each written by an internationally leading expert in the field, and presents state-of-the-art and recent advances in nucleic acid synthetic modifications, ... Leer más

    $143.99 USD

  • The Functional Nucleus

    Edición de Graham Dellaire, David P. Bazett-Jones ...
    This book gives an in-depth overview on nuclear structure and function. It clearly shows that the epigenome and the three-dimensional organization of the nucleus are not independent properties. The intimate relationship between the location and the epigenetic modifications of gene loci is highlighted. Finally, it shows that the complex three-dimensional organization of the nucleus is not just of ... Leer más

    $188.99 USD

  • Intrabodies

    Basic Research and Clinical Gene Therapy Applications

    Edición de Wayne A. Marasco ...

    $89.99 USD

  • Decoding Neural Circuit Structure and Function

    Cellular Dissection Using Genetic Model Organisms

    Edición de Arzu Çelik, Mathias F. Wernet ...
    Series series Biomedical and Life Sciences (R0)
    This book offers representative examples from fly and mouse models to illustrate the ongoing success of the synergistic, state-of-the-art strategy, focusing on the ways it enhances our understanding of sensory processing. The authors focus on sensory systems (vision, olfaction), which are particularly powerful models for probing the development, connectivity, and function of neural circuits, to ... Leer más

    $143.99 USD

  • Stem Cells in Modeling Human Genetic Diseases

    Edición de Mayana Zatz, Oswaldo Keith Okamoto ...
    Series series Biomedical and Life Sciences (R0)
    While most stem cell books focus on basic aspects and/or cell therapy, this book emphasizes the relevance of stem cells obtained from patients, the so-called “patients in a petri dish” as tools to investigate human genetic diseases for which there are no available effective treatment. Chapters embrace several examples of the use of iPS cell technology, a recent Nobel Prize-winning scientific ... Leer más

    $89.99 USD