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1 - 12 de 12 resultados para “marc damelin”
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  • Innovations for Next-Generation Antibody-Drug Conjugates

    Edición de Marc Damelin ...
    Series series Medicine (R0)
    Antibody-drug conjugates (ADCs) stand at the verge of a transformation. Scores of clinical programs have yielded only a few regulatory approvals, but a wave of technological innovation now empowers us to overcome past technical challenges. This volume focuses on the next generation of ADCs and the innovations that will enable them. The book inspires the future by integrating the field’s history ... Leer más

    $143.09 USD

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  • Clinical Trials

    Study Design, Endpoints and Biomarkers, Drug Safety, and FDA and ICH Guidelines

    de Tom Brody ...
    Clinical Trials: Study Design, Endpoints and Biomarkers, Drug Safety, and FDA and ICH Guidelines is a practical guidebook for those engaged in clinical trial design. This book details the organizations and content of clinical trials, including trial design, safety, endpoints, subgroups, HRQoL, consent forms and package inserts. It provides extensive information on both US and international ... Leer más

    $71.99 USD

  • Detection and Quantification of Antibodies to Biopharmaceuticals

    Practical and Applied Considerations

    Edición de Michael G. Tovey ...
    The definitive book on the neutralization of recombinant biopharmaceuticalsRecombinant biopharmaceuticals are an important tool for treating a range of illnesses; however, their efficacy can be severely impaired by their immunogenicity. When introduced into the body, these pharmaceuticals can cause the immune system to produce anti-drug antibodies (ADAs) that neutralize their effects.The first and ... Leer más

    $144.00 USD

  • Antigen Retrieval Immunohistochemistry Based Research and Diagnostics

    Edición de Shan-Rong Shi, Clive R. Taylor ...
    Series Libro 5 - Wiley Series in Biomedical Engineering and Multi-Disciplinary Integrated Systems
    The most complete, up-to-date reference on antigen retrieval and immunohistochemistryAn antigen is a substance that prompts the generation of antibodies and can cause an immune response. The antigen retrieval (AR) technique is in wide use across the globe, and is a critical technique used in medical diagnosis of disease, particularly clinical targeted cancer treatment.Antigen Retrieval ... Leer más

    $156.00 USD

  • Platelet Proteomics

    Principles, Analysis, and Applications

    Edición de Yotis Senis, Ángel García-Alonso ...
    Series Libro 47 - Wiley Series on Mass Spectrometry
    The purpose of the book is to introduce platelets, and their functional role in thrombotic and cardiovascular disease, justifying the relevance of platelet proteomics research. Focus then shifts to the recent developments on mass spectrometry (MS)-based proteomics. This chapter shows potential applications for platelet proteomics not yet carried out. It includes examples of post-translational ... Leer más

    $107.00 USD

  • Flow Cytometry in Drug Discovery and Development

    Edición de Virginia Litwin, Philip Marder ...
    This book covers the unique application of flow cytometry in drug discovery and development. The first section includes two introductory chapters, one on flow cytometry and one on biomarkers, as well as a chapter on recent advances in flow cytometry. The second section focuses on the unique challenges and added benefits associated with the use of flow cytometry in the drug development process. The ... Leer más

    $129.00 USD

  • Recombinant Antibodies for Immunotherapy

    Edición de Melvyn Little, PhD ...
    Recombinant Antibodies for Immunotherapy provides a comprehensive overview of the field of monoclonal antibodies (mAbs), a market that has grown tremendously in recent years. Twenty-five articles by experienced and innovative authors cover the isolation of specific human mAbs, humanization, immunogenicity, technologies for improving efficacy, 'arming' mAbs, novel alternative Ab constructs, ... Leer más

    $104.99 USD

  • Polypharmacology in Drug Discovery

    Edición de Jens-Uwe Peters ...
    An essential outline of the main facets of polypharmacology in drug discovery researchExtending drug discovery opportunities beyond the "one drug, one target" philosophy, a polypharmacological approach to the treatment of complex diseases is emerging as a hot topic in both industry and academic research. Polypharmacology in Drug Discovery presents an overview of the various facets of ... Leer más

    $127.00 USD

  • Therapeutic Drug Monitoring

    Newer Drugs and Biomarkers

    Edición de Amitava Dasgupta ...
    Therapeutic Drug Monitoring: Newer Drugs and Biomarkers features timely topics such as the monitoring of classical and newer drugs, pharmacogenomics and the application of biomarkers in therapeutic drug monitoring. This reference also discusses the limitations of current commercially available immunoassays for therapeutic monitoring. It presents new and sophisticated techniques used for proper ... Leer más

    $150.99 USD

  • Predictive Toxicology in Drug Safety

    Edición de Jinghai J. Xu, Laszlo Urban ...
    According to the Institute of Medicine (IOM) and U.S. Food and Drug Administration (FDA), 'developing new scientific approaches to detecting, understanding, predicting and preventing adverse events' was a critical path to the future of drug safety. This book brings together a collection of state-of-the-art chapters, written by experts in the drug safety field. It provides information on the ... Leer más

    $131.99 USD

  • Analogue-based Drug Discovery II

    Edición de C. Robin Ganellin, János Fischer ...
    Born out of a project of the IUPAC's committee on Medicinal Chemistry and Drug Development, this reference addresses past and current strategies for successful drug analog development, extending the previously published volume by nine new analog classes and eight case studies. Like its precursor, this volume also contains a general section discussing universally applicable strategies for analog ... Leer más

    $212.00 USD

  • Therapeutic Monoclonal Antibodies

    From Bench to Clinic

    Edición de Zhiqiang An ...
    70-chapter authoritative reference that covers therapeutic monoclonal antibody discovery, development, and clinical applications while incorporating principles, experimental data, and methodologies.First book to address the discovery and development of antibody therapeutics in their entirety.Most chapters contain experimental data to illustrate the principles described in them.Authors provide ... Leer más

    $198.00 USD