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  • Prostasin in Human Health and Disease

    de Li-Mei Chen ...
    The formation of placenta can be viewed as a controlled process of inflammation or cancer development in which cell proliferation, invasion, and immune surveillance or evasion are promoted in a time- and space-specific manner. This suggests that the functions of prostasin are mainly active in pathophysiological conditions, more so than those in basic or normal physiological conditions. The ... Leer más

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  • Genetic Diagnosis of Endocrine Disorders

    Edición de Roy E. Weiss, Samuel Refetoff ...
    Since the beginning of the current century, endocrine disease diagnosis and treatment have moved beyond the standard hormone measurements. While, indeed elevated thyroid hormone levels or low insulin levels signal a specific endocrine disease, correct diagnosis (and therefore correct treatment) depends on an understanding of the molecular basis for the disease. This book presents the "bench to ... Leer más

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  • Antiviral Drugs

    From Basic Discovery Through Clinical Trials

    This book focuses on new small molecule approaches to combat viral infections. The chapters describe the discovery and development from bench through the clinic of relatively recently-approved antiviral drugs and compounds in advanced clinical development. Organized by a virus (such as HIV, HCV, RSV, influenza, HBV and CMV) and written by top academic and industrial authorities in the field, the ... Leer más

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  • Gene Therapy of Cancer

    Translational Approaches from Preclinical Studies to Clinical Implementation

    Gene therapy as a treatment for cancer is at a critical point in its evolution. Exciting new developments in gene targeting and vector technology, coupled with results from the first generation of preclinical and clinical studies have led to the design and testing of new therapeutic approaches. The Third Edition of Gene Therapy of Cancer provides crucial updates on the basic and applied sciences ... Leer más

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  • Novel Approaches and Strategies for Biologics, Vaccines and Cancer Therapies

    Edición de Manmohan Singh, Maya Salnikova ...
    Novel Approaches and Strategies for Biologics, Vaccines and Cancer Therapies takes a look at the current strategies, successes and challenges involved with the development of novel formulations of biologics, vaccines and cancer therapy. This thorough reference on the latest trends in the development of diverse modalities will appeal to a broad community of scientists, students and clinicians. ... Leer más

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  • Recent Advances in Cancer Research and Therapy

    Cancer continues to be one of the major causes of death throughout the developed world, which has led to increased research on effective treatments. Because of this, in the past decade, rapid progress in the field of cancer treatment has been seen. Recent Advances in Cancer Research and Therapy reviews in specific details some of the most effective and promising treatments developed in research ... Leer más

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  • Oncoviruses: Cellular and Molecular Virology

    de Abubakar Yaro ...
    Oncoviruses are cancer-causing viruses that play a leading role in the development of certain cancers by contributing to genetic changes that result in the disruption of cell cycle machinery, interfering with certain key functions such as cell growth. Human viral Oncogenesis has common traits: 1. Oncoviruses are required but not sufficient for cancer development. 2. Virus-associated cancers appear ... Leer más

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  • Paul's Fundamental Immunology

    Selected as a Doody's Core Title for 2022! Defining the field of immunology for 40 years, Paul’s Fundamental Immunology continues to provide detailed, authoritative, up-to-date information that uniquely bridges the gap between basic immunology and the disease process. The fully revised 8th edition maintains the excellence established by Dr. William E. Paul, who passed away in 2015, and is now ... Leer más

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  • Emerging Cancer Therapy

    Microbial Approaches and Biotechnological Tools

    Series Libro 3 - Wiley Series in Biotechnology and Bioengineering
    Explores current and emerging applications of microbes as cancer-fighting agentsWILEY SERIES IN BIOTECHNOLOGY AND BIOENGINEERINGAnurag S. Rathore, Series EditorToday, treatment options for cancer patients typically include surgery, radiation therapy, immunotherapy, and chemotherapy. While these therapies have saved lives and reduced pain and suffering, cancer still takes millions of lives every ... Leer más

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  • Antiviral Drug Strategies

    Series Libro 50 - Methods & Principles in Medicinal Chemistry
    By focusing on general molecular mechanisms of antiviral drugs rather than therapies for individual viruses, this ready reference provides the critical knowledge needed to develop entirely novel therapeutics and to target new viruses.It begins with a general discussion of antiviral strategies, followed by a broad survey of known viral targets, such as reverse transcriptases, proteases, ... Leer más

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  • Oligonucleotide-Based Drugs and Therapeutics

    Preclinical and Clinical Considerations for Development

    Edición de Nicolay Ferrari, Rosanne Seguin ...
    A comprehensive review of contemporary antisense oligonucleotides drugs and therapeutic principles, methods, applications, and researchOligonucleotide-based drugs, in particular antisense oligonucleotides, are part of a growing number of pharmaceutical and biotech programs progressing to treat a wide range of indications including cancer, cardiovascular, neurodegenerative, neuromuscular, and ... Leer más

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  • Adult Stem Cells

    Edición de Kursad Turksen ...
    Series series Stem Cell Biology and Regenerative Medicine
    Adult Stem Cells, second edition, takes a critical look at issues concerning the developmental or differentiation potential for a variety of tissue types and for specific adult stem cell types. Since the first edition appeared a decade ago, our understanding of adult stem cells, and more specifically tissue-specific adult stem cells, has advanced tremendously. And an increased interest in ... Leer más

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