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1 - 12 de 12 resultados para “k h graefe”
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  • Recent Advances in Neuropharmacology

    Edición de H. Bönisch, K.-H. Graefe, S.Z. Langer, E. Schömig ...
    Series series Medicine (R0)
    This volume is dedicated to Professor Ullrich Trendelenburg. It contains the proceedings of a symposium which was held in his honour on the occasion of his retirement and took place March 22-24, 1991 in Wiirzburg. Ullrich Trendelenburg was the head of the Department of Pharmacology at Wiirzburg University from 1968 till the end of March 1991. He is famous internationally for his contributions to ... Leer más

    $49.49 USD

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  • Cortico-Subcortical Dynamics in Parkinson’s Disease

    Edición de Kuei-Yuan Tseng ...
    Series series Contemporary Neuroscience
    The striatum is the principal input structure of the basal ganglia. Numerically, the great majority of neurons in the striatum are spiny projection neurons, which produce the inhibitory output of the striatum to the globus pallidum and substantia nigra. The major glutamatergic afferents to the striatum from the cerebral cortex make monosynaptic contact with spiny projection neurons. The ... Leer más

    $98.99 USD

  • Behavioral Neurobiology of Chronic Pain

    Edición de Bradley K. Taylor, David P. Finn ...
    Series series Biomedical and Life Sciences (R0)
    Pain is the most common reason people seek medical help. The treatment of chronic pain is a major unmet clinical need and its impact on health, well-being, society and the economy is immense. Pain is an integrative, whole-systems (patho)physiological phenomenon and behavioural neuroscience plays a key role in advancing our understanding of pain. This volume brings together a series of ... Leer más

    $143.99 USD

  • 5-HT2C Receptors in the Pathophysiology of CNS Disease

    Edición de Giuseppe Di Giovanni, Ennio Esposito, Vincenzo Di Matteo ...
    Series series Biomedical and Life Sciences (R0)
    Part of Springer’s “The Receptors,” series, this text is the first ever overview on the research of 5-HT2c receptors. 5-HT2c receptor research has been productive for twenty-five years, but recent years have seen an extraordinary increase in both amount produced and insight gained. 5-HT2c is a prominent central serotonin receptor subtype widely expressed within the central and the peripheral ... Leer más

    $188.99 USD

  • The Dopamine Receptors

    Edición de Kim Neve ...
    Series series Biomedical and Life Sciences (R0)
    As sites of action for drugs used to treat schizophrenia and Parkinson’s disease, dopamine receptors are among the most validated drug targets for neuropsychiatric disorders. Dopamine receptors are also drug targets or potential targets for other disorders such as substance abuse, depression, Tourette’s syndrome, and attention deficit hyperactivity disorder. Updated from the successful first ... Leer más

    $260.99 USD

  • Functional Selectivity of G Protein-Coupled Receptor Ligands

    New Opportunities for Drug Discovery

    Edición de Kim Neve ...
    Series series Biomedical and Life Sciences (R0)
    Functional selectivity refers to the ability of different ligands acting at one receptor subtype to activate multiple signaling pathways in unique combinations; that is, one drug can be an agonist at pathway A and an antagonist or partial agonist at pathway B, and another drug can have the reverse profile. Functional selectivity has profound implications for drug development, for chemical biology, ... Leer más

    $98.99 USD

  • endoCANNABINOIDS

    Actions at Non-CB1/CB2 Cannabinoid Receptors

    Edición de Mary E. Abood, Roger G Sorensen, Nephi Stella ...
    Series series Biomedical and Life Sciences (R0)
    This book is intended as a scientific resource for cannabinoid researchers carrying out animal and human experiments, and for those who are interested in learning about future directions in cannabinoid research. Additionally, this book may be of value to investigators currently working outside the field of cannabinoid research who have an interest in learning about these compounds and their ... Leer más

    $98.99 USD

  • Cilia and Nervous System Development and Function

    Edición de Kerry L. Tucker, Tamara Caspary ...
    Series series Biomedical and Life Sciences (R0)
    Cilia are tiny microtubule-based organelles projecting from the plasma membrane of practically all cells in the body. In the past 10 years a flurry of research has indicated a crucial role of this long-neglected organelle in the development and function of the central nervous system. A common theme of these studies is the critical dependency of signal transduction of the Sonic hedgehog, and more ... Leer más

    $143.99 USD

  • Microglia in the Regenerating and Degenerating Central Nervous System

    Edición de Wolfgang J. Streit ...
    Over the past decade, the study of microglial cells has gained increasing importance, in particular for those working in the fields of degeneration and regeneration. Microglia in the Regenerating and Degenerating CNS supports the assertion that understanding microglial biology could perhaps be pivotal for unraveling the pathogenetic mechanisms that underlie Alzheimer's disease, currently the most ... Leer más

    $143.99 USD

  • Oxidative Neural Injury

    Edición de Sigrid C. Veasey ...
    Series series Biomedical and Life Sciences (R0)
    Twenty-five years ago, Earl R. Stadtman, PhD discovered that specific enzymes regulating metabolism can be inactivated by oxidation [1]. He later showed that age-related oxidative modification contributes, at least in part, to age-related loss of function of the enzymes [2, 3]. Dr. Stadtman broke the ground for a new field of study to discover how oxidative stress contributes in significant ways ... Leer más

    $98.99 USD

  • Gasotransmitters: Physiology and Pathophysiology

    Edición de Anton Hermann, Guzel F. Sitdikova, Thomas M. Weiger ...
    Series series Biomedical and Life Sciences (R0)
    Since the epochal discovery of the radical and highly toxic gas nitric oxide (NO) as a signaling molecule, two other no less toxic gases – carbon monoxide (CO) and hydrogen sulfide (H2S) – have been found to also be involved in a plethora of physiological and pathophysiological functions. The gases termed gasotransmitters play an increasingly important role in understanding how signalling into and ... Leer más

    $143.09 USD

  • Appetite Control

    Edición de Hans-Georg Joost ...
    Series series Biomedical and Life Sciences (R0)
    The volume ‘Appetite Control’ provides a comprehensive description of the mechanisms controlling food intake, and thereby energy balance, in the mammalian organism. During the last decade, research in this area has produced a remarkable wealth of information and has characterized the function of numerous peptides, transmitters, and receptors in appetite control. Dysfunction of these circuits leads ... Leer más

    $287.09 USD