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  • Alzheimer's Disease: Biology, Biophysics And Computational Models

    Alzheimer's disease (AD) is the leading cause of dementia and, unfortunately, remains incurable. The social, emotional and financial implications of AD are immeasurable, and about 47 million people worldwide are affected by AD or other forms of dementia. As lifespans are improved by healthcare systems worldwide, age-associated neurodegenerative diseases are imposing an increasing challenge to ... Leer más

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    Edición de Alexander E. Knight ...
    Single molecule techniques, including single molecule fluorescence, optical tweezers, and scanning probe microscopy, allow for the manipulation and measurement of single biological molecules within a live cell or in culture. These approaches, amongst the most exciting tools available in biology today, offer powerful new ways to elucidate biological function, both in terms of revealing mechanisms ... Leer más

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  • Drug-Acceptor Interactions

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    Drug-Acceptor Interactions: Modeling theoretical tools to test and evaluate experimental equilibrium effects suggests novel theoretical tools to test and evaluate drug interactions seen with combinatorial drug therapy. The book provides an in-depth, yet controversial, exploration of existing tools for analysis of dose-response studies at equilibrium or steady state. The book is recommended reading ... Leer más

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  • Applications of Flow Cytometry in Stem Cell Research and Tissue Regeneration

    A much-needed primer on the use of laser flow cytometry for stem cell analysisLaser flow cytometry is a powerful tool for rapid analysis of cells for marker expression, cell cycle position, proliferation, and apoptosis. However, no resources specifically address the use of this methodology for the study of stem cells; this is especially important as stem cell analysis involves specialized methods ... Leer más

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  • Proteomic and Metabolomic Approaches to Biomarker Discovery

    Edición de Haleem J. Issaq ...
    Proteomic and Metabolomic Approaches to Biomarker Discovery demonstrates how to leverage biomarkers to improve accuracy and reduce errors in research. Disease biomarker discovery is one of the most vibrant and important areas of research today, as the identification of reliable biomarkers has an enormous impact on disease diagnosis, selection of treatment regimens, and therapeutic monitoring. ... Leer más

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  • Biotransformation and Metabolite Elucidation of Xenobiotics

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    Edición de Ala F. Nassar ...
    The goal of this book is to improve the readers' knowledge of metabolite elucidation in drug metabolism by exposing them to in depth coverage of the biotransformation of xenobiotics, strategies for identifying and characterizing metabolites, FDA guidelines, and case studies on how to improve the decision-making process in structural modification of drug candidates to reduce toxicity.The book ... Leer más

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  • Synapse: A Tutorial Study Guide

    de Nicoladie Tam ...
    “Synapse” is a part of the college-level Principles of Biology course series and the Neuropsychopharmacology course series textbooks. It is a tutorial written in questions and answers format to describe the anatomy and physiology of the synapses and synaptic connections between neurons.It is a study guide with in-depth explanations. Each section is a modular unit that is self-contained for easy ... Leer más

    $2.99 USD o gratis con Kobo Plus

  • Metabolomics in Practice

    Successful Strategies to Generate and Analyze Metabolic Data

    Unlike other handbooks in this emerging field, this guide focuses on the challenges and critical parameters in running a metabolomics study, including such often-neglected issues as sample preparation, choice of separation and detection method, recording and evaluating data as well as method validation. By systematically covering the entire workflow, from sample preparation to data processing, the ... Leer más

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  • Platelet Proteomics

    Principles, Analysis, and Applications

    Series Libro 47 - Wiley Series on Mass Spectrometry
    The purpose of the book is to introduce platelets, and their functional role in thrombotic and cardiovascular disease, justifying the relevance of platelet proteomics research. Focus then shifts to the recent developments on mass spectrometry (MS)-based proteomics. This chapter shows potential applications for platelet proteomics not yet carried out. It includes examples of post-translational ... Leer más

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  • Lipidomics

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    Edición de Kim Ekroos ...
    Focusing on the practical applications, this user-oriented guide presents current technologies and strategies for systems-level lipidanalysis, going beyond basic research to concentrate on commercial uses of lipidomics in biomarker and diagnostic development, as wellas within pharmaceutical drug discovery and development. The editor and authors have experience of the most recent analytical ... Leer más

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  • Cell Press Reviews: Core Concepts in Cell Biology

    Edición de Cell Press ...
    Series series Cell Press Reviews Series
    Written by leading cell biologists and curated by Cell Press editors, reviews in the Cell Press Reviews: Core Concepts in Cell Biology publication informs, inspires, and connects cell biologists at all stages in their careers with timely, comprehensive insight into the most recent exciting developments across cell biology and hot topics within core areas of the field including: - Signaling ... Leer más

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  • Optogenetics

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    Edición de Krishnarao Appasani ...
    Discovered little more than a decade ago, optogenetics - a revolutionary technique combining genetic and optical methods to observe and control the function of neurons - is now a widely used research tool. Optogenetics-driven research has led to insights into Parkinson's disease and other neurological and psychiatric disorders. With contributions from leaders and innovators from both academia and ... Leer más

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