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  • Targeting Autophagy in Cancer Therapy

    Edición de Jin-Ming Yang ...
    Series series Medicine (R0)
    This volume will detail the current state and perspectives of autophagy-based cancer therapy. Covering a wide range of topics, it will include an overview of autophagy as a therapeutic target in cancer, autophagy modulators as cancer therapeutic agents, implications of micro-RNA-regulated autophagy in cancer therapy, modulation of autophagy through targeting PI3 kinase in cancer therapy, targeting ... Leer más

    $89.99 USD

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  • DNA Repair of Cancer Stem Cells

    Series series Biomedical and Life Sciences (R0)
    The existence of ‘cancer stem cells’ (CSCs) has been a topic of heated debate for the last few years within the field of cancer biology. Their continuous characterization in a variety of solid tumors has lead to an abundance of evidence supporting their existence. CSCs are believed to be responsible for resistance against conventional treatment regimes of chemotherapy and radiation, ultimately, ... Leer más

    $143.99 USD

  • The DNA Damage Response: Implications on Cancer Formation and Treatment

    Edición de Yosef Shiloh, Kum Kum Khanna ...
    Series series Biomedical and Life Sciences (R0)
    The ?eld of cellular responses to DNA damage has attained widespread recognition and interest in recent years commensurate with its fundamental role in the ma- tenance of genomic stability. These responses, which are essential to preventing cellular death or malignant transformation, are organized into a sophisticated s- tem designated the “DNA damage response”. This system operates in all living ... Leer más

    $143.99 USD

  • Pharmacogenomics of Human Drug Transporters

    Clinical Impacts

    Sets the foundation for safer, more effective drug therapiesWith this book as their guide, readers will discover how to apply our current understanding of the pharmacogenomics of drug transporters to advance their own drug discovery and development efforts. In particular, the book explains how new findings in the field now enable researchers to more accurately predict drug interactions and adverse ... Leer más

    $148.00 USD

  • Stress-Induced Mutagenesis

    Edición de David Mittelman ...
    Series series Biomedical and Life Sciences (R0)
    The discovery of stress-induced mutagenesis has changed ideas about mutation and evolution, and revealed mutagenic programs that differ from standard spontaneous mutagenesis in rapidly proliferating cells. The stress-induced mutations occur during growth-limiting stress, and can include adaptive mutations that allow growth in the otherwise growth-limiting environment. The stress responses increase ... Leer más

    $143.99 USD

  • Long Non-coding RNAs in Human Disease

    Edición de Kevin V. Morris ...
    Series series Biomedical and Life Sciences (R0)
    This volume focuses on the roles of long non-coding RNAs (lncRNAs) in contexts ranging from human cancers to cardiovascular disease and ageing. The role of lncRNAs in X-inactivation and those lncRNAs derived from pseudogenes, past retroelements integrated within the human genome, as well as the role these pseudogene-derived lncRNAs play in cancer development are discussed in detail. Further, the ... Leer más

    $89.99 USD

  • The Long and Short Non-coding RNAs in Cancer Biology

    Edición de Erwei Song ...
    Series series Biomedical and Life Sciences (R0)
    The book conveys a comprehensive knowledge of long and short ncRNAs in cancer regulation and their potentials as diagnostic biomarkers and therapeutic targets. Topics covered include the molecular mechanisms of various classes of ncRNAs (with emphasis on long non-coding RNAs and microRNAs) in cancer, the functional roles of ncRNAs in regulating different cancer hallmarks (including proliferation, ... Leer más

    $143.99 USD

  • The Hippo Signaling Pathway and Cancer

    Edición de Moshe Oren, Yael Aylon ...
    Series series Biomedical and Life Sciences (R0)
    The Hippo signaling pathway is rapidly gaining recognition as an important player in organ size control and tumorigenesis, and many leading scientists are showing increased interest in this growing field and it's relation to cancer. The chapters in this volume cover virtually all aspects of tumor biology, because members of the Hippo Pathway have been associated with numerous well-established cell ... Leer más

    $143.99 USD

  • Epigenetic Regulation in Overcoming Chemoresistance

    Edición de Chunfu Wu, Lihui Wang ...
    Series Libro 16 - Cancer Sensitizing Agents for Chemotherapy
    Epigenetic Regulation in Overcoming Chemoresistance, Volume 19, explains how epigenetic agents can enhance the chemotherapy sensitivity of diverse types of cancers. The book provides a comprehensive delineation and the recent development of the scientific studies on the epigenetic regulation in enhancing chemo-sensitivity. In addition, it discusses several topics such as DNA methyltransferase ... Leer más

    $157.99 USD

  • Cancer and Noncoding RNAs

    Series Libro 1 - Translational Epigenetics
    Cancer and Noncoding RNAs offers an in-depth exploration of noncoding RNAs and their role in epigenetic regulation of complex human disease, most notably cancer. In addition to examining microRNAs, this volume provides a unique evaluation of more recently profiled noncoding RNAs now implicated in carcinogenesis, including lncRNAs, piRNAs, circRNAs, and tRNAs, identifying differences in function ... Leer más

    $179.99 USD

  • Autophagy and Cancer

    Edición de Hong-Gang Wang ...
    Series series Medicine (R0)
    With the explosion of information on autophagy in cancer, this is an opportune time to speed the efforts to translate our current knowledge about autophagy regulation into better understanding of its role in cancer. This book will cover the latest advances in this area from the basics, such as the molecular machinery for autophagy induction and regulation, up to the current areas of interest such ... Leer más

    $143.99 USD

  • Post-transcriptional Mechanisms in Endocrine Regulation

    This book examines how post-transcriptional mechanisms control endocrine function. This includes newly identified regulatory mechanisms involved in hormone biosynthesis, control of hormone receptors and the outputs of hormone mediated signal transduction. Chapters address endocrine hormones including protein peptide/peptide, steroid, and non-steroidal hormones. The impacts of these mechanisms on ... Leer más

    $170.99 USD