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  • Molecular Biology of Long Non-coding RNAs

    Edición de Jeff Coller, Ahmad M. Khalil ...
    Series series Biomedical and Life Sciences (R0)
    Long non-coding RNAs (lnc)RNAs have emerged as a new paradigm in epigenetic regulation of the genome. Thousands of lncRNAs have been identified and observed in a wide range of organisms. Unlike mRNA, lncRNA have no protein-coding capacity. So, while their function is not entirely clear, they may serve as key organizers of protein complexes that allow for higher order regulatory events. Discovering ... Leer más

    $134.99 USD

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  • Perimenopause: How to Create A Healthy Physical & Emotional Life During the Change

    de Heather Rose ...
    Perimenopause--one of women's most deterred words. It's quite understandable, though, as experiencing perimenopause will bring a lot of changes to a woman's body. Some women are lucky not to have those symptoms meddle with their lives, but some aren't so fortunate; their loved ones also have to adapt to the changes - especially about those mood swings - that they face. But it does not have to be ... Leer más

    $4.99 USD

  • Multiple Sclerosis

    Series series The Facts
    Multiple Sclerosis (MS) is thought to affect almost 2.5 million people worldwide. With the arrival of several new MS drugs and increased availability of information on the internet, many people are confronted by an overwhelming number of information sources about how best to manage their condition. This new book explains, in a clear and accessible way, what is currently known about MS. It provides ... Leer más

    $17.99 USD

  • Introduction to Molecular Medicine

    How will increased understanding of the human genome affect our ability to diagnose and treat disease? The subject of recombinant DNA technology is no longer limited to the research laboratory; it is being discussed in ever-widening medical circles. Introduction to Molecular Medicine is especially written for the physician who is not a genetics expert but wishes to understand this new science and ... Leer más

    $80.99 USD

  • Cystogenesis

    Edición de Jong Hoon Park, Curie Ahn ...
    Series series Biomedical and Life Sciences (R0)
    Autosomal Dominant Polycystic Kidney Disease (ADPKD) is a highly prevalent hereditary renal disorder in which fluid-filled cysts are appeared in both kidneys. Main causative genes of ADPKD are PKD1 and PKD2, encoding for polycystin-1 (PC1) and polycystin-2 (PC2) respectively. Those proteins are localized on primary cilia and function as mechanosensor in response to the fluid flow, translating ... Leer más

    $89.99 USD

  • Bioinformatics for High Throughput Sequencing

    Series series Biomedical and Life Sciences (R0)
    Next generation sequencing is revolutionizing molecular biology. Owing to this new technology it is now possible to carry out a panoply of experiments at an unprecedented low cost and high speed. These go from sequencing whole genomes, transcriptomes and small non-coding RNAs to description of methylated regions, identification protein – DNA interaction sites and detection of structural variation. ... Leer más

    $143.09 USD

  • Tobacco Smoking Addiction: Epidemiology, Genetics, Mechanisms, and Treatment

    de Ming D. Li ...
    Series series Biomedical and Life Sciences (R0)
    This book provides the most recent knowledge on almost all key aspects of the health impact of tobacco smoking. Its 21 chapters focus on both preclinical and clinical studies. The contents are broad, covering the epidemiology of tobacco smoking; genetic epidemiology; identification of susceptibility genomic regions, genes, and pathways as determined by both human and animal studies; evolutionary ... Leer más

    $98.99 USD

  • Safety and Efficacy of Gene-Based Therapeutics for Inherited Disorders

    Edición de Nicola Brunetti-Pierri ...
    Series series Biomedical and Life Sciences (R0)
    In this book, leading international experts analyze state-of-the-art advances in gene transfer vectors for applications in inherited disorders and also examine the toxicity profiles of these methods. The authors discuss the strengths and weaknesses of available vectors in the clinical setting, and specifically focus on the challenges and possible solutions that researchers are testing in order to ... Leer más

    $143.99 USD

  • Cancer Stem Cells: Emerging Concepts and Future Perspectives in Translational Oncology

    Edición de Sadegh Babashah ...
    Series series Biomedical and Life Sciences (R0)
    The concept of cancer stem cells has great clinical implications. This is due to the fact that small subpopulations of these cells have been identified in a variety of neoplastic conditions ranging from solid tumors to liquid malignancies. Although there are some huge gaps in our current understanding of the role played by cancer stem cells in cancer biology, a growing body of evidence provides ... Leer más

    $143.99 USD

  • Trinucleotide Diseases and Instability

    Edición de Ben A. Oostra ...
    Series series Biomedical and Life Sciences (R0)
    Till recently, mutations in genes were described in textbooks as deletions or point mutations. These mutations can be inherited from a parent or they are de novo alterations. The discovery in 1991 that human disease can be caused by large-scale ex pansion of highly unstable trinucleotide repeats has elucidated a new mutation mechanism, heritable unstable DNA. In the subsequent years more then 10 ... Leer más

    $49.99 USD

  • Cancer Genomics

    Molecular Classification, Prognosis and Response Prediction

    Edición de Ulrich Pfeffer ...
    Series series Biomedical and Life Sciences (R0)
    The combination of molecular biology, engineering and bioinformatics has revolutionized our understanding of cancer revealing a tight correlation of the molecular characteristics of the primary tumor in terms of gene expression, structural alterations of the genome, epigenetics and mutations with its propensity to metastasize and to respond to therapy. It is not just one or a few genes, it is the ... Leer más

    $188.99 USD