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  • Introduction to Analysis of Variance

    Design, Analyis & Interpretation

    Having trouble finding a book that shows you not only how to analyze data but also how to collect the data appropriately and fully interpret the analysis, too? Here′s a new book that does all this in a particularly readable fashion. Turner and Thayer′s text:Shows how to design an experiment in the best possible way to investigate the topic of interestExplains which associated analysis will best ... Leer más

    $70.99 USD

  • Key Statistical Concepts in Clinical Trials for Pharma

    Series series Biomedical and Life Sciences (R0)
    This Brief discusses key statistical concepts that facilitate the inferential analysis of data collected from a group of individuals participating in a pharmaceutical clinical trial, the estimation of their clinical significance in the general population of individuals likely to be prescribed the drug if approved, and the related decision-making that occurs at both the public health level (by ... Leer más

    $49.99 USD

  • Cardiovascular Safety in Drug Development and Therapeutic Use

    New Methodologies and Evolving Regulatory Landscapes

    Series series Medicine (R0)
    At a time when the field of cardiac safety is going through important changes, this unique book provides the rationale for, and cutting-edge explanations of, new regulatory landscapes that will likely govern cardiac safety assessments globally for the foreseeable future. Exposure-response modeling is already being accepted by regulatory agencies in lieu of the traditional Thorough QT/QTc Study, ... Leer más

    $71.99 USD

  • Cardiovascular Reactivity and Stress

    Patterns of Physiological Response

    Series series The Springer Series in Behavioral Psychophysiology and Medicine
    This book is an articulate, concise, contemporary introduction to the study of important variables underlying cardiovascular reactivity. Its strength is in the combination of a scholarly but nonpedantic approach to cardiovascular psychophysiology and a solid understanding of be havioral medicine approaches to the study of hypertension. The topics covered are central to the study of relationships ... Leer más

    $89.99 USD

  • Individual Differences in Cardiovascular Response to Stress

    Series series Perspectives on Individual Differences
    Demonstrating that the magnitude and pattern of cardiovascular response to stress varies markedly between individuals, this work discusses the mechanisms by which the cardiovascular system is mobilized during stress, the determinants of individual differences, and the pathophysiological processes by which responses to stress may lead to cardiovascular disease. Behavioral scientists from a variety ... Leer más

    $143.99 USD

  • Behavior Genetic Approaches in Behavioral Medicine

    Series series Perspectives on Individual Differences
    Leading researchers examine how behavior genetics provides crucial insights into genetic and environmental influences in the development of biobehavioral disorders. These influences are illustrated by using the examples of cardiovascular disease, obesity and eating disorders, alcohol use and abuse, and smoking behavior. Contributors discuss the relevance of molecular genetic approaches and twin ... Leer más

    $143.99 USD

  • New Drug Development

    An Introduction to Clinical Trials: Second Edition

    Series series Biomedical and Life Sciences (R0)
    New Drug Development: Second Edition provides an overview of the design concepts and statistical practices involved in therapeutic drug development. This wide spectrum of activities begins with identifying a potentially useful drug candidate that can perhaps be used in the treatment or prevention of a condition of clinical concern, and ends with marketing approval being granted by one or more ... Leer más

    $323.99 USD

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  • Pharmaco-Imaging in Drug and Biologics Development

    Fundamentals and Applications

    Series series Biomedical and Life Sciences (R0)
    The volume aim to be a comprehensive overview of the drug and biologic development process that is often called “the valley of death” (pre-IND through approval) where high costs of studies and high rates of product failure are part of the drug development landscape. Imaging tools can serve in this period by adding high value data, the images and the kinetic information they can provide, and cost ... Leer más

    $152.99 USD

  • RNA Interference from Biology to Therapeutics

    Edición de Kenneth A. Howard ...
    Series series Biomedical and Life Sciences (R0)
    The enormous potential of siRNA as a therapeutic has led to an explosion of interest from the scientific community. There has been intense interest from Big Pharma to capitalise on this new technology but the fact remains that delivery is a key determinant in realizing the full clinical potential of RNA interference. There is an urgent need for better delivery methods to take this technology ... Leer más

    $215.99 USD

  • Drug Delivery to the Brain

    Physiological Concepts, Methodologies and Approaches

    Series series Biomedical and Life Sciences (R0)
    The development of new CNS drugs is notoriously difficult. Drugs must reach CNS target sites for action and these sites are protected by a number of barriers, the most important being the blood –brain barrier (BBB). Many factors are therefore critical to consider for CNS drug delivery, e.g. active/passive transport across the BBB, intra-brain distribution, and central/systemic pharmacokinetics, to ... Leer más

    $170.99 USD

  • Proteases in Physiology and Pathology

    Using a multidisciplinary approach, this book describes the biochemical mechanisms associated with dysregulation of proteases and the resulting pathophysiological consequences. It highlights the role and regulation of different types of proteases as well as their synthetic and endogenous inhibitors. The role of proteases was initially thought to be limited to general metabolic digestion. However, ... Leer más

    $143.99 USD

  • Molecular Imaging of Small Animals

    Instrumentation and Applications

    Edición de Habib Zaidi ...
    Series series Biomedical and Life Sciences (R0)
    This book examines the fundamental concepts of multimodality small-animal molecular imaging technologies and their numerous applications in biomedical research. Driven primarily by the widespread availability of various small-animal models of human diseases replicating accurately biological and biochemical processes in vivo, this is a relatively new yet rapidly expanding field that has excellent ... Leer más

    $260.99 USD