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  • Model-Assisted Bayesian Designs for Dose Finding and Optimization

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    Bayesian adaptive designs provide a critical approach to improve the efficiency and success of drug development that has been embraced by the US Food and Drug Administration (FDA). This is particularly important for early phase trials as they form the basis for the development and success of subsequent phase II and III trials.The objective of this book is to describe the state-of-the-art model ... Leer más

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  • Bayesian Adaptive Methods for Clinical Trials

    Series series Chapman & Hall/CRC Biostatistics Series
    Already popular in the analysis of medical device trials, adaptive Bayesian designs are increasingly being used in drug development for a wide variety of diseases and conditions, from Alzheimer's disease and multiple sclerosis to obesity, diabetes, hepatitis C, and HIV. Written by leading pioneers of Bayesian clinical trial designs, Bayesian Adapti ... Leer más

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