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1 - 12 de 12 resultados para “holger kalthoff”
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  • Death Receptors and Cognate Ligands in Cancer

    Edición de Holger Kalthoff ...
    Series series Biomedical and Life Sciences (R0)
    Death receptors play a central role in directing apoptosis in mammalian cells. This process of active cell death is important for a number of biological processes, e.g. for the regulation of the immune system. Death receptors are cell surface receptors that transmit apoptotic signals initiated by corresponding death ligands. Many complex signaling pathways are activated and apoptosis is the final ... Leer más

    $188.99 USD

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  • Stem Cells

    Scientific Facts and Fiction

    de Anja van de Stolpe, Bernard Roelen, Hans Clevers, Christine L. Mummery ...
    Recent advances in the fields of medicine and technology have led to the development of stem cell therapy. A stem cell is a cell that has the potential to develop into many different types of cell in the body. It has the ability to divide and copy itself and at least one other specialized type of cell. Stem Cells was written to provide information about the development of stem cell therapy, which ... Leer más

    $74.99 USD

  • DNA Repair of Cancer Stem Cells

    Edición de Elain Hurt, Stephanie M Cabarcas, Lesley A Mathews ...
    Series series Biomedical and Life Sciences (R0)
    The existence of ‘cancer stem cells’ (CSCs) has been a topic of heated debate for the last few years within the field of cancer biology. Their continuous characterization in a variety of solid tumors has lead to an abundance of evidence supporting their existence. CSCs are believed to be responsible for resistance against conventional treatment regimes of chemotherapy and radiation, ultimately, ... Leer más

    $143.99 USD

  • Cystogenesis

    Edición de Jong Hoon Park, Curie Ahn ...
    Series series Biomedical and Life Sciences (R0)
    Autosomal Dominant Polycystic Kidney Disease (ADPKD) is a highly prevalent hereditary renal disorder in which fluid-filled cysts are appeared in both kidneys. Main causative genes of ADPKD are PKD1 and PKD2, encoding for polycystin-1 (PC1) and polycystin-2 (PC2) respectively. Those proteins are localized on primary cilia and function as mechanosensor in response to the fluid flow, translating ... Leer más

    $89.09 USD

  • Trends in Stem Cell Proliferation and Cancer Research

    Edición de Rodrigo R. Resende, Henning Ulrich ...
    Series series Biomedical and Life Sciences (R0)
    The book will discuss the molecular mechanisms of cancer diseases, stem cell proliferation and transformation into cancer cells beyond the physiological processes that occur in normal stem cell biology. Some of the key oncogenic events in cancer and their signaling pathways that regulate cell division cycle progression will be described considering prospects for using such knowledge in advanced ... Leer más

    $188.09 USD

  • MFG-E8 and Inflammation

    Edición de Ping Wang ...
    Series series Biomedical and Life Sciences (R0)
    After the discovery of milk fat globule-epidermal growth factor-factor 8 (MFG-E8) about two decades ago, a new era of delineating its potential beneficial role in several inflammatory diseases has begun to spout from the bench to translational research. In MFG-E8 and Inflammation, the editor and contributors have gathered a remarkable collection covering novel discoveries on the rapidly growing ... Leer más

    $143.99 USD

  • Interaction of Immune and Cancer Cells

    Edición de Magdalena Klink ...
    Series series Biomedical and Life Sciences (R0)
    The tumor environment is a dynamic network that includes cancer cells, immune cells, fibroblasts, endothelial cells, extracellular matrix, cytokines and receptors. The aim of this book is to summarize the role of these components, especially immune cells, in tumor suppression and/or progression and describe in detail why tumor cells can survive and spread in spite of the antitumor response of ... Leer más

    $143.99 USD

  • Novel Approaches to Treatment of Osteoporosis

    Edición de R.G.G. Russell, T.M. Skerry, U. Kollenkirchen ...
    Series series Medicine (R0)
    Osteoporosis affects a growing number of the population. Current treatments are based on prevention of further bone loss after the condition is diagnosed, often because a fracture has occurred. Treatments in the future will aim at healing osteoporosis by improving bone mass and quality. This book describes novel discoveries and research which will allow bone to be restored after it has been lost. ... Leer más

    $49.49 USD

  • Contextualizing Systems Biology

    Presuppositions and Implications of a New Approach in Biology

    de Martin Döring, Imme Petersen, Anne Brüninghaus, Regine Kollek ...
    Series series Biomedical and Life Sciences (R0)
    This collective monograph aims at contributing to an improved understanding of the epistemic presumptions, sociocultural implications and historically backgrounds of the newly emerging and currently expanding approach of systems biology. In doing so, it offers empirically grounded, valuable and reflexive information about a paradigmatic shift in the biosciences for a wide range of scientists ... Leer más

    $143.09 USD

  • Intrabodies

    Basic Research and Clinical Gene Therapy Applications

    Edición de Wayne A. Marasco ...

    $89.99 USD

  • Our Molecular Nature

    The Body’s Motors, Machines and Messages

    de David S. Goodsell ...
    Series series Biomedical and Life Sciences (R0)
    Molecular Nature is a richly illustrated guide to the extraordinary diversity of molecules that are responsible for life. David Goodsell, author of the highly-praised book, The Machinery of Life, has synthesized a vast amount of data in a manner that is accessible to the general reader. Molecular Nature examines topics ranging from the shape of cells to the molecules responsible for digestion, ... Leer más

    $49.49 USD

  • Hypoxia and Cancer

    Biological Implications and Therapeutic Opportunities

    Edición de Giovanni Melillo ...
    Series series Biomedical and Life Sciences (R0)
    The imbalance between rapidly proliferating tumor cells and inadequate and inefficient tumor vasculature leads to a decrease in oxygen levels (hypoxia and/or anoxia) in tumor tissues. Intra-tumor hypoxia profoundly affects the biological behavior of cancer cells, which become resistant to conventional therapies and acquire a more invasive and metastatic phenotype. Hypoxia is a hallmark of the ... Leer más

    $143.99 USD