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1 - 12 de 12 resultados para “hilmar weinmann”
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  • Protein Degradation with New Chemical Modalities

    Successful Strategies in Drug Discovery and Chemical Biology

    Edición de Hilmar Weinmann, Craig Crews ...
    Series Libro 74 - Drug Discovery Series
    Targeting protein degradation using small molecules is one of the most exciting small-molecule therapeutic strategies in decades and a rapidly growing area of research. In particular, the development of proteolysis targeting chimera (PROTACs) as potential drugs capable of recruiting target proteins to the cellular quality control machinery for elimination has opened new avenues to address ... Leer más

    $224.99 USD

  • Organocatalysis

    Edición de Manfred Reetz, Benjamin List, Stefan Jaroch, Hilmar Weinmann ...
    Series series Springer Nature Proceedings excluding Computer Science

    $251.09 USD

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  • RNA Interference (RNAi)

    de Wiley ...
    Series series Life Science Research Fundamentals
    The 2006 Nobel Prize in Physiology or Medicine was awarded to Andrew Z. Fire and Craig C. Mello for their discovery of RNA interference (RNAi). RNAi is a biological process in which RNA molecules can silence (inhibit) or up- or down-regulate gene expression, typically by causing the destruction of specific messenger RNA (mRNA) molecules. This collection of articles begins with an introduction to ... Leer más

    $27.99 USD

  • Epigenetics in Cancer

    de Wiley ...
    Series series Life Science Research Fundamentals
    Epigenetics is the study of heritable changes in gene expression or cellular phenotype, caused by mechanisms other than changes in the DNA sequence. Examples include DNA methylation and histone modification. These changes may remain through cell divisions and multiple generations. Epigenetic differences among individuals may account for some of the differences between monozygotic (identical) twins ... Leer más

    $29.00 USD

  • Chemical Genomics

    Edición de Haian Fu, PhD ...
    Advances in chemistry, biology and genomics coupled with laboratory automation and computational technologies have led to the rapid emergence of the multidisciplinary field of chemical genomics. This edited text, with contributions from experts in the field, discusses the new techniques and applications that help further the study of chemical genomics. The beginning chapters provide an overview of ... Leer más

    $113.99 USD

  • Peptides

    Synthesis, Structures, and Applications

    Edición de Bernd Gutte ...
    In recent years, research has shown the importance of peptides in neuroscience, immunology, and cell biology. Active research programs worldwide are now engaged in developing peptide-based drugs and vaccines using modification of natural peptides and proteins, design of artificial peptides and peptide mimetics, and screening of peptide and phage libraries. In this comprehensive book, the authors ... Leer más

    $65.99 USD

  • Advances in Nucleic Acid Therapeutics

    Edición de Sudhir Agrawal, Michael J Gait ...
    Series Libro 68 - Drug Discovery Series
    The sequencing of the human genome and subsequent elucidation of the molecular pathways that are important in the pathology of disease have provided unprecedented opportunities for the development of new therapeutics. Nucleic acid-based drugs have emerged in recent years to yield extremely promising candidates for drug therapy to a wide range of diseases. Advances in Nucleic Acid Therapeutics is a ... Leer más

    $247.99 USD

  • Peptide-based Drug Discovery

    Challenges and New Therapeutics

    Edición de Ved Srivastava ...
    Series Libro 59 - Drug Discovery Series
    With potentially high specificity and low toxicity, biologicals offer promising alternatives to small-molecule drugs. Peptide therapeutics have again become the focus of innovative drug development efforts backed up by a resurgence of venture funds and small biotechnology companies.What does it take to develop a peptide-based medicine? What are the key challenges and how are they overcome? What ... Leer más

    $225.99 USD

  • Medicinal Chemistry Approaches to Personalized Medicine

    de Raimund Mannhold, Hugo Kubinyi, Gerd Folkers ...
    Series Libro 59 - Methods & Principles in Medicinal Chemistry
    Edited by two renowned medicinal chemists who have pioneered the development of personalized therapies in their respective fields, this authoritative analysis of what is already possible is the first of its kind, and the only one to focus on drug development issues.Numerous case studies from the first generation of "personalized drugs" are presented, highlighting the challenges and opportunities ... Leer más

    $126.00 USD

  • Structural Aspects Of Protein Synthesis (2nd Edition)

    de Anders Liljas, Mans Ehrenberg ...
    Series Libro 1 - Series In Structural Biology
    This highly illustrated book provides an up-to-date description of the structure and function of the translation system including ribosomes, tRNAs, translation factors, antibiotics and aminoacyl-tRNA synthetases.Research on translation is undergoing rapid changes and is receiving significant attention as evidenced by the Nobel Prize in Chemistry 2009. The structural research by crystallography and ... Leer más

    $63.99 USD

  • GPCR Molecular Pharmacology and Drug Targeting

    Shifting Paradigms and New Directions

    Edición de Annette Gilchrist ...
    G protein-coupled receptors (GPCRs) are a large protein family of transmembrane receptors vital in dictating cellular responses. GPCRs are involved in many diseases, but are also the target of around half of all modern medicinal drugs. Shifting Paradigms in G Protein Coupled Receptors takes a look at the way GPCRs are examined today, how they react, how their mutations lead to disease, and the ... Leer más

    $168.00 USD

  • Protein Surface Recognition

    Approaches for Drug Discovery

    Edición de Ernest Giralt, Mark Peczuh, Xavier Salvatella ...
    A new perspective on the design of molecular therapeutics is emerging. This new strategy emphasizes the rational complementation of functionality along extended patches of a protein surface with the aim of inhibiting protein/protein interactions. The successful development of compounds able to inhibit these interactions offers a unique chance to selectively intervene in a large number of key ... Leer más

    $142.00 USD