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1 - 12 de 16 resultados para “helmut buschmann”
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  • Drug Development Approaches for Poorly Soluble Compounds

    de Helmut Buschmann, Jörg Holenz, Christa Müller ...
    Series Libro 85 - Methods & Principles in Medicinal Chemistry
    Ten proven strategies to overcome solubility challenges in drug developmentPoor water solubility prevents drug candidates from reaching their therapeutic targets, causing promising compounds to fail during development. Drug Development Approaches for Poorly Soluble Compounds presents ten distinct strategies for overcoming this challenge, from altering drug structure and creating prodrugs to ... Leer más

    $122.00 USD

  • RNA as a Drug Target

    The Next Frontier for Medicinal Chemistry

    de Raimund Mannhold, Helmut Buschmann, Jörg Holenz ...
    Series series Methods & Principles in Medicinal Chemistry
    Discover a new paradigm in drug discovery that greatly expands the space of addressable drug targets and potential novel drugsExisting paradigms for drug discovery have focused largely on enzymes and other proteins as drug targets. In recent years, however, different varieties of ribonucleic acids have emerged as a viable focus for target-based drug discovery, with the potential to revolutionize ... Leer más

    $142.00 USD

  • Solid State Development and Processing of Pharmaceutical Molecules

    Salts, Cocrystals, and Polymorphism

    de Michael Gruss, Raimund Mannhold, Helmut Buschmann, Jörg Holenz ...
    Series series Methods & Principles in Medicinal Chemistry
    Solid State Development and Processing of Pharmaceutical MoleculesA guide to the lastest industry principles for optimizing the production of solid state active pharmaceutical ingredientsSolid State Development and Processing of Pharmaceutical Molecules is an authoritative guide that covers the entire pharmaceutical value chain. The authors—noted experts on the topic—examine the importance of the ... Leer más

    $172.00 USD

  • Open Access Databases and Datasets for Drug Discovery

    de Raimund Mannhold, Helmut Buschmann, Jörg Holenz ...
    Series series Methods & Principles in Medicinal Chemistry
    Open Access Databases and Datasets for Drug DiscoveryTimely resource discussing the future of data-driven drug discovery and the growing number of open-source databasesWith an overview of 90 freely accessible databases and datasets on all aspects of drug design, development, and discovery, Open Access Databases and Datasets for Drug Discovery is a comprehensive guide to the vast amount of “free ... Leer más

    $142.00 USD

  • Targeted Drug Delivery

    de Raimund Mannhold, Helmut Buschmann, Yogeshwar Bachhav, Jörg Holenz ...
    Series series Methods & Principles in Medicinal Chemistry
    Targeted Drug DeliveryNovel approaches in targeted drug delivery for both small molecule and biopharmaceutical drugsTargeted Drug Delivery explores a new frontier in drug research that has become a focus for developing novel medications. The work discusses a wide range of approaches for targeting small molecules as well as peptide and macromolecular drugs, from prodrugs to drug conjugates to drug ... Leer más

    $142.00 USD

  • Flow and Microreactor Technology in Medicinal Chemistry

    de Raimund Mannhold, Helmut Buschmann, Jörg Holenz, Esther Alza ...
    Series series Methods & Principles in Medicinal Chemistry
    Learn to master a powerful technology to enable a faster drug discovery workflowThe ultimate dream for medicinal chemists is the ability to synthesize new drug-like compounds with the push of a button. The key to synthesizing chemical compounds more quickly and accurately lies in computer-controlled technologies that can be optimized by machine learning. Recent developments in computer-controlled ... Leer más

    Antes $140.00 USD Ahora $125.00 USD

  • New Drug Development for Known and Emerging Viruses

    de Helga Rübsamen-Schaeff, Helmut Buschmann ...
    Series series Methods & Principles in Medicinal Chemistry
    Discusses how to fight Ebola, SARS Corona, and other known or emerging human viruses by building on the successes in antiviral therapy of the past decadesWritten by leading medicinal chemists from academia and industry, this book discusses the entire field of antiviral drug discovery and development from a medicinal chemistry perspective, focusing on antiviral drugs, targets, and viral disease ... Leer más

    $172.00 USD

  • Target Discovery and Validation

    Methods and Strategies for Drug Discovery

    de Raimund Mannhold, Helmut Buschmann, Jörg Holenz ...
    Series series Methods & Principles in Medicinal Chemistry
    The modern drug developers? guide for making informed choices among the diverse target identification methodsTarget Discovery and Validation: Methods and Strategies for Drug Discovery offers a hands-on review of the modern technologies for drug target identification and validation. With contributions from noted industry and academic experts, the book addresses the most recent chemical, biological, ... Leer más

    $151.00 USD

  • Early Drug Development

    Bringing a Preclinical Candidate to the Clinic

    de Raimund Mannhold, Helmut Buschmann, Jörg Holenz ...
    Series series Methods & Principles in Medicinal Chemistry
    This one-stop reference systematically covers key aspects in early drug development that are directly relevant to the discovery phase and are required for first-in-human studies.Its broad scope brings together critical knowledge from many disciplines, ranging from process technology to pharmacology to intellectual property issues.After introducing the overall early development workflow, the ... Leer más

    $290.00 USD

  • Neglected Tropical Diseases

    Drug Discovery and Development

    de Raimund Mannhold, Helmut Buschmann, Jörg Holenz ...
    Series series Methods & Principles in Medicinal Chemistry
    A drug discovery reference to the crippling tropical diseases that affect more than 1 billion people.Neglected Tropical Diseases is the first book of its kind to offer a guide that follows the World Health Organization?s list of neglected tropical diseases. The authors?all are experts on the topic?address the development of effective treatments for 12 crippling infectious diseases that affect ... Leer más

    $146.00 USD

  • Innovative Dosage Forms

    Design and Development at Early Stage

    de Raimund Mannhold, Helmut Buschmann, Jörg Holenz ...
    Series series Methods & Principles in Medicinal Chemistry
    Teaches future and current drug developers the latest innovations in drug formulation design and optimizationThis highly accessible, practice-oriented book examines current approaches in the development of drug formulations for preclinical and clinical studies, including the use of functional excipients to enhance solubility and stability. It covers oral, intravenous, topical, and parenteral ... Leer más

    $156.00 USD

  • Transporters as Drug Targets

    de Raimund Mannhold, Gerd Folkers, Helmut Buschmann ...
    Series series Methods & Principles in Medicinal Chemistry
    As opposed to other books on the topic, this volume is unique in also covering emerging transporter targets.Following a general introduction to the importance of targeting transporter proteins with drugs, the book systematically presents individual transporter classes and explains their pharmacology and physiology. The text covers all transporter families with known or suspected importance as drug ... Leer más

    $151.00 USD