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1 - 12 de 23 resultados para “gerd folkers”
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  • Flugsommer

    de Gerd Folkers ...
    Nürnberg 1834: Zwei junge Männer kämpfen leidenschaftlich um die Zukunft der Luftfahrt. Der eine schwört auf den steuerbaren Ballon, der andere träumt vom Flugzeug. Was als Freundschaft begann, wird zum erbitterten Wettstreit. Medienrummel, Crowdfunding über Zeitungsanzeigen, üble Nachrede – kein Mittel ist ihnen zu schäbig, um den einstigen Freund zu vernichten. Während Carl Spitzweg das ... Leer más

    $29.99 USD

  • Fragment-based Drug Discovery

    Lessons and Outlook

    de Raimund Mannhold, Hugo Kubinyi, Gerd Folkers ...
    Series series Methods & Principles in Medicinal Chemistry
    From its origins as a niche technique more than 15 years ago, fragment-based approaches have become a major tool for drug and ligand discovery, often yielding results where other methods have failed. Written by the pioneers in the field, this book provides a comprehensive overview of current methods and applications of fragment-based discovery, as well as an outlook on where the field is headed ... Leer más

    $151.00 USD

  • Thermodynamics and Kinetics of Drug Binding

    de Raimund Mannhold, Hugo Kubinyi, Gerd Folkers ...
    Series series Methods & Principles in Medicinal Chemistry
    This practical reference for medicinal and pharmaceutical chemists combines the theoretical background with modern methods as well as applications from recent lead finding and optimization projects.Divided into two parts on the thermodynamics and kinetics of drug-receptor interaction, the text provides the conceptual and methodological basis for characterizing binding mechanisms for drugs and ... Leer más

    $151.00 USD

  • Lead Generation

    Methods and Strategies

    de Raimund Mannhold, Hugo Kubinyi, Gerd Folkers ...
    Series series Methods & Principles in Medicinal Chemistry
    In this comprehensive two-volume resource on the topic senior lead generation medicinal chemists present a coherent view of the current methods and strategies in industrial and academic lead generation. This is the first book to combine both standard and innovative approaches in comparable breadth and depth, including several recent successful lead generation case studies published here for the ... Leer más

    $275.00 USD

  • Animal Models for Human Cancer

    Discovery and Development of Novel Therapeutics

    de Raimund Mannhold, Hugo Kubinyi, Gerd Folkers ...
    Series series Methods & Principles in Medicinal Chemistry
    Based on results from the past ten years, this ready reference systematically describes how to prepare, carry out, and evaluate animal studies for cancer therapies, addressing the widely recognized lack of reliable and reproducible results.Following a short historical introduction and a discussion of the ethics surrounding animal experiments, the book describes correct study design as well as the ... Leer más

    $129.00 USD

  • Protein Therapeutics

    de Raimund Mannhold, Gerd Folkers, Helmut Buschmann ...
    Series series Methods & Principles in Medicinal Chemistry
    In this practice-oriented two volume handbook, professionals from some of the largest biopharmaceutical companies and top academic researchers address the key concepts and challenges in the development of protein pharmaceuticals for medicinal chemists and drug developers of all trades.Following an introduction tracing the rapid development of the protein therapeutics market over the last decade, ... Leer más

    $282.00 USD

  • Transporters as Drug Targets

    de Raimund Mannhold, Gerd Folkers, Helmut Buschmann ...
    Series series Methods & Principles in Medicinal Chemistry
    As opposed to other books on the topic, this volume is unique in also covering emerging transporter targets.Following a general introduction to the importance of targeting transporter proteins with drugs, the book systematically presents individual transporter classes and explains their pharmacology and physiology. The text covers all transporter families with known or suspected importance as drug ... Leer más

    $151.00 USD

  • Medicinal Chemistry Approaches to Personalized Medicine

    de Raimund Mannhold, Hugo Kubinyi, Gerd Folkers ...
    Series Libro 59 - Methods & Principles in Medicinal Chemistry
    Edited by two renowned medicinal chemists who have pioneered the development of personalized therapies in their respective fields, this authoritative analysis of what is already possible is the first of its kind, and the only one to focus on drug development issues.Numerous case studies from the first generation of "personalized drugs" are presented, highlighting the challenges and opportunities ... Leer más

    $126.00 USD

  • Microwaves in Organic and Medicinal Chemistry

    de C. Oliver Kappe, Alexander Stadler, Doris Dallinger, Raimund Mannhold, Hugo Kubinyi, Gerd Folkers ...
    Series Libro 52 - Methods & Principles in Medicinal Chemistry
    Tailored to the needs of medicinal and natural products chemists, the second edition of this unique handbook brings the contents up to speed,almost doubling the amount of chemical information with an additional volume.As in the predecessor, a short introductory section covers the theoretical background and evaluates currently available instrumentation andequipment. The main part of the book then ... Leer más

    $170.00 USD

  • Drug Metabolism Prediction

    de Raimund Mannhold, Hugo Kubinyi, Gerd Folkers ...
    Series Libro 63 - Methods & Principles in Medicinal Chemistry
    The first professional reference on this highly relevant topic, for drug developers, pharmacologists and toxicologists.The authors provide more than a systematic overview of computational tools and knowledge bases for drug metabolism research and their underlying principles. They aim to convey their expert knowledge distilled from many years of experience in the field. In addition to the ... Leer más

    $148.00 USD

  • Phosphodiesterases and Their Inhibitors

    de Raimund Mannhold, Hugo Kubinyi, Gerd Folkers ...
    Series Libro 61 - Methods & Principles in Medicinal Chemistry
    Written by the pioneers of Viagra, the first blockbuster PDE inhibitor drug.Beginning with a review of the first wave of phosphodiesterase (PDE) inhibitors, this book focuses on new and emerging PDE targets and their inhibitors. Drug development options for all major human PDE families are discussed and cover diverse therapeutic fields, such as neurological/psychiatric, cardiovascular/metabolic, ... Leer más

    $142.00 USD

  • Scaffold Hopping in Medicinal Chemistry

    de Raimund Mannhold, Hugo Kubinyi, Gerd Folkers ...
    Series Libro 58 - Methods & Principles in Medicinal Chemistry
    This first systematic treatment of the concept and practice of scaffold hopping shows the tricks of the trade and provides invaluable guidance for the reader's own projects.The first section serves as an introduction to the topic by describing the concept of scaffolds, their discovery, diversity and representation, and their importance for finding new chemical entities. The following part ... Leer más

    $126.00 USD