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  • Experimental Evolution

    The Making of a Modern Science

    Experimental Evolution: The Making of a Modern Science connects molecular biology/biochemistry with ecology/evolution to show how molecular mechanisms and ecological processes work together to drive evolutionary change. The book's four-part structure, covering Preliminaries, The Molecular Basis of Fitness, The Ecological Context of Competition, and Cooperation and Conflict, helps those with a ... Leer más

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  • The Origins of Order

    Self-Organization and Selection in Evolution

    Stuart Kauffman here presents a brilliant new paradigm for evolutionary biology, one that extends the basic concepts of Darwinian evolution to accommodate recent findings and perspectives from the fields of biology, physics, chemistry and mathematics. The book drives to the heart of the exciting debate on the origins of life and maintenance of order in complex biological systems. It focuses on the ... Leer más

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  • Population Genetics

    This book aims to make population genetics approachable, logical and easily understood. To achieve these goals, the book’s design emphasizes well explained introductions to key principles and predictions. These are augmented with case studies as well as illustrations along with introductions to classical hypotheses and debates.Pedagogical features in the text include:Interact boxes that guide ... Leer más

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  • Chemical Synthetic Biology

    Chemistry plays a very important role in the emerging field of synthetic biology. In particular, chemical synthetic biology is concerned with the synthesis of chemical structures, such as proteins, that do not exist in nature. With contributions from leading international experts, Chemical Synthetic Biology shows how chemistry underpins synthetic biology. The book is an essential guide to this ... Leer más

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  • Metabolic Engineering

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    Metabolic engineering is a new field with applications in the production of chemicals, fuels, materials, pharmaceuticals, and medicine at the genetic level. The field's novelty is in the synthesis of molecular biology techniques and the tools of mathematical analysis, which allow rational selection of targets for genetic modification through measurements and control of metabolic fluxes. The ... Leer más

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  • More Dead Ends and Detours

    En Route to Successful Total Synthesis

    Success comes in many forms and in synthesis it can be a failure that results in their ultimate successful solutions. This long-awaited sequel to "Dead Ends and Detours" retains the proven concept while featuring over 20 new case studies of failed strategies and their (successful) solutions in natural product total synthesis. Additionally, computational models are used to discuss the problem in ... Leer más

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  • Mutation-Driven Evolution

    de Masatoshi Nei ...
    The purpose of this book is to present a new mechanistic theory of mutation-driven evolution based on recent advances in genomics and evolutionary developmental biology. The theory asserts, perhaps somewhat controversially, that the driving force behind evolution is mutation, with natural selection being of only secondary importance. The word 'mutation' is used to describe any kind of change in ... Leer más

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  • The Foundations of Population Genetics

    An accessible but rigorous treatment of the theoretical foundations of population genetics.Population genetics—the branch of evolutionary biology concerned with understanding how and why populations’ genetic compositions change over time—rests on a well-developed theoretical foundation that draws on genetics, mathematics, and computer science. This textbook provides an approachable but rigorous ... Leer más

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  • The Origins of Evolutionary Innovations

    A Theory of Transformative Change in Living Systems

    The history of life is a nearly four billion year old story of transformative change. This change ranges from dramatic macroscopic innovations such as the evolution of wings or eyes, to a myriad of molecular changes that form the basis of macroscopic innovations. We are familiar with many examples of innovations (qualitatively new phenotypes that provide a critical benefit) but have no systematic ... Leer más

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  • Biocatalysts and Enzyme Technology

    This second edition of a bestselling textbook offers an instructive and comprehensive overview of our current knowledge of biocatalysis and enzyme technology.The book now contains about 40% more printed content. Three chapters are completely new, while the others have been thoroughly updated, and a section with problems and solutions as well as new case studies have been added.Following an ... Leer más

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  • Microbial Life History

    The Fundamental Forces of Biological Design

    A powerful framework for understanding how natural selection shapes adaptation and biological designDesign and diversity are the two great challenges in the study of life. Microbial Life History draws on the latest advances in microbiology to describe the fundamental forces of biological design and apply these evolutionary processes to a broad diversity of traits in microbial metabolism and ... Leer más

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  • Synthetic Biology

    Tools and Applications

    Edición de Huimin Zhao ...
    Synthetic Biology provides a framework to examine key enabling components in the emerging area of synthetic biology. Chapters contributed by leaders in the field address tools and methodologies developed for engineering biological systems at many levels, including molecular, pathway, network, whole cell, and multi-cell levels. The book highlights exciting practical applications of synthetic ... Leer más

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