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  • Peroxisome Proliferator Activated Receptors: From Basic Science to Clinical Applications

    Series series Medicine (R0)
    Peroxisome Proliferator Activated Receptors (PPARs) attract great attention in light of the wide spectrum of genes of biological and medical relevance identified as under their control. As a consequence, our knowledge of the role of these receptors in physiology and pathology continues to grow at a fast pace and PPARs have become an interesting target for the treatment of many pathological ... Leer más

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  • Semaphorins

    A Diversity of Emerging Physiological and Pathological Activities

    Edición de Atsushi Kumanogoh ...
    Series series Biomedical and Life Sciences (R0)
    This book presents the current concepts of semaphorin biology. In the early 1990s, semaphorins were originally identified as axon guidance cues that function during neuronal development. However, cumulative findings have clarified that they have diverse functions in many physiological processes, including cardiogenesis, angiogenesis, vasculogenesis, osteoclastogenesis, retinal homeostasis, and ... Leer más

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  • Arachidonate Remodeling and Inflammation

    Series series Progress in Inflammation Research
    Arachidonic acid (AA) and other 20 or 22-carbon polyunsaturated fatty acids (PUFAs) are precursors of lipid mediators of inflammation known as eicosanoids. These mediators are critical in disease processes and in regulating normal cell function. Remodeling is important in maintaining homeostasis and in regulating cell function by dictating how PUFAs are converted to lipid mediators of inflammation ... Leer más

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  • Vascular Engineering

    New Prospects of Vascular Medicine and Biology with a Multidiscipline Approach

    Edición de Kazuo Tanishita, Kimiko Yamamoto ...
    Series series Medicine (R0)
    This book describes the fundamental biology and mechanics of the vasculature and examines how this knowledge has underpinned the development of new clinical modalities, including endovascular treatment and vascularization of reconstructed tissue for regenerative medicine. Vascular engineering is a multidisciplinary field integrating vascular biology, hemodynamics, biomechanics, tissue engineering, ... Leer más

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  • Imaging Mass Spectrometry

    Protocols for Mass Microscopy

    Edición de Mitsutoshi Setou ...
    Series series Biomedical and Life Sciences (R0)
    Addressing the widespread need for a practical guide to imaging mass spectrometry (IMS), this book presents the protocols of IMS technology. As that technology expands, research groups around the world continue its development. Pharmaceutical companies are using IMS for drug analyses to study pharmacokinetics and medical properties of drugs. Drug research and disease-related biomarker screening ... Leer más

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  • Endocrine Disruptors and Puberty

    Series series Medicine (R0)
    Endocrine disruption represents one of the most controversial environmental issues of our time. Mounting evidence stemming from more than 10 years of experimental, epidemiological and clinical studies has transformed the once generally discounted subject of endocrine disruptors into an issue of tremendous concern not only within the scientific community but among society as a whole. Following ... Leer más

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  • Biology of Vascular Smooth Muscle: Vasoconstriction and Dilatation

    de Yuansheng Gao ...
    Series series Biomedical and Life Sciences (R0)
    This book provides a concise yet comprehensive review of the morphological, biochemical, electrical, mechanical, and metabolic properties of vascular smooth muscle, the regulation of vascular activities and the intracellular signaling involved. It particularly focuses on recently identified vasoactive agents, enzymes and transduction mechanisms. It also discusses the latest findings in the ... Leer más

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  • Antiplatelet Agents

    Series series Biomedical and Life Sciences (R0)
    Antiplatelet therapy is the cornerstone of treatment of ischemic cardiovascular disease and over the last few years spectacular advancements in this field have been recorded. This is the first comprehensive handbook entirely dedicated to all the aspects of antiplatelet therapy. The book is divided into three main sections, pathophysiology, pharmacology and therapy, for a total of 23 chapters. A ... Leer más

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  • Diabetes - Perspectives in Drug Therapy

    Edición de Mathias Schwanstecher ...
    Series series Biomedical and Life Sciences (R0)
    The chapters of this book report cutting-edge research on molecular events in adiposity and type 2 diabetes, thus opening the way for innovative drug-based therapeutic strategies. It addresses all those who wish to keep in touch with recent developments in the field. ... Leer más

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  • Endocrine Emergencies

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    Edición de Lynn Loriaux ...
    Series series Medicine (R0)
    Endocrine Emergencies: Recognition and Treatment offers a state-of-the-art update on the management of endocrine, diabetic, and metabolic emergencies. Developed by renowned experts, this comprehensive and easy to read title brings the field fully up to date, setting a high standard for diagnosis and treatment in each category. All chapters begin with a summary that presents, in concentrated form, ... Leer más

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  • Methods in Endothelial Cell Biology

    Edición de Hellmut G. Augustin ...
    Series series Biomedical and Life Sciences (R0)
    Endothelial cell biology has developed into a vibrant discipline and has become a critical instrument to study several disease processes on the cellular and molecular level. It is now widely recognized that dysfunctions of normal endothelial cell homeostasis are involved in some of the most important human diseases, including ischemic heart diseases, hypertension, atherosclerosis, tumors, diabetes ... Leer más

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