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  • Long Acting Animal Health Drug Products

    Fundamentals and Applications

    Series series Biomedical and Life Sciences (R0)
    Long acting veterinary formulations play a significant role in animal health, production and reproduction within the animal health industry. Such technologies offer beneficial advantages to the veterinarian, farmer and pet owner. These advantages have resulted in them growing in popularity in recent years.The pharmaceutical scientist is faced with many challenges when innovating new products in ... Leer más

    $188.99 USD

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  • Sterile Product Development

    Formulation, Process, Quality and Regulatory Considerations

    Series series Biomedical and Life Sciences (R0)
    This comprehensive book encompasses various facets of sterile product development. Key concepts relevant to the successful development of sterile products are illustrated through case studies and are covered under three sections in this book:• Formulation approaches that discuss a variety of dosage forms including protein therapeutics, lipid-based controlled delivery systems, PEGylated ... Leer más

    $323.99 USD

  • Pharmaco-Imaging in Drug and Biologics Development

    Fundamentals and Applications

    Series series Biomedical and Life Sciences (R0)
    The volume aim to be a comprehensive overview of the drug and biologic development process that is often called “the valley of death” (pre-IND through approval) where high costs of studies and high rates of product failure are part of the drug development landscape. Imaging tools can serve in this period by adding high value data, the images and the kinetic information they can provide, and cost ... Leer más

    $152.99 USD

  • Validation of Alternative Methods for Toxicity Testing

    Edición de Chantra Eskes, Maurice Whelan ...
    Series series Biomedical and Life Sciences (R0)
    This book provides information on best practices and new thinking regarding the validation of alternative methods for toxicity testing. It covers the validation of experimental and computational methods and integrated approaches to testing and assessment. Validation strategies are discussed for methods employing the latest technologies such as tissue-on-a-chip systems, stem cells and ... Leer más

    $170.99 USD

  • The Challenge of CMC Regulatory Compliance for Biopharmaceuticals

    de John Geigert ...
    This book highlights the challenges facing quality assurance/quality control (QA/QC) in today's biopharmaceutical environment and presents the strategic importance and value generated by QA/QC for their involvement in control of manufacturing. It will put into perspective the need for a graded approach to QA/QC from early clinical trials through market approval. Since the first edition published ... Leer más

    $170.99 USD

  • A Picture is Worth a Thousand Tables

    Graphics in Life Sciences

    Edición de Andreas Krause, Michael OConnell ...
    This book is devoted to the graphics of patient data: good graphs enabling straight¬forward and intuitive interpretation, efficient creation, and straightforward interpretation. We focus on easy access to graphics of patient data: the intention is to show a large variety of graphs for different phases of drug development, together with a description of what the graph shows, what type of data it ... Leer más

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  • RNA Interference from Biology to Therapeutics

    Edición de Kenneth A. Howard ...
    Series series Biomedical and Life Sciences (R0)
    The enormous potential of siRNA as a therapeutic has led to an explosion of interest from the scientific community. There has been intense interest from Big Pharma to capitalise on this new technology but the fact remains that delivery is a key determinant in realizing the full clinical potential of RNA interference. There is an urgent need for better delivery methods to take this technology ... Leer más

    $215.99 USD

  • Understanding Depression

    Volume 1. Biomedical and Neurobiological Background

    Edición de Yong-Ku Kim ...
    Series series Medicine (R0)
    This book, in two volumes, focuses on contemporary issues and dilemmas in relation to depression. The aim is to equip readers with an up-to-date understanding of the clinical and neurobiological underpinnings of depression and their relation to clinical manifestations and the development of more effective treatments. This first volume is devoted specifically to biomedical and neurobiological ... Leer más

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  • Drug Delivery to the Brain

    Physiological Concepts, Methodologies and Approaches

    Series series Biomedical and Life Sciences (R0)
    The development of new CNS drugs is notoriously difficult. Drugs must reach CNS target sites for action and these sites are protected by a number of barriers, the most important being the blood –brain barrier (BBB). Many factors are therefore critical to consider for CNS drug delivery, e.g. active/passive transport across the BBB, intra-brain distribution, and central/systemic pharmacokinetics, to ... Leer más

    $170.99 USD

  • Melt Extrusion

    Materials, Technology and Drug Product Design

    Series series Biomedical and Life Sciences (R0)
    This volume provides readers with the basic principles and fundamentals of extrusion technology and a detailed description of the practical applications of a variety of extrusion processes, including various pharma grade extruders. In addition, the downstream production of films, pellets and tablets, for example, for oral and other delivery routes, are presented and discussed utilizing melt ... Leer más

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  • Biomolecular Interfaces

    Interactions, Functions and Drug Design

    Series series Biomedical and Life Sciences (R0)
    The book focuses on the aqueous interface of biomolecules, a vital yet overlooked area of biophysical research. Most biological phenomena cannot be fully understood at the molecular level without considering interfacial behavior.The author presents conceptual advances in molecular biophysics that herald the advent of a new discipline, epistructural biology, centered on the interactions of water ... Leer más

    $49.99 USD

  • Proteases in Physiology and Pathology

    Using a multidisciplinary approach, this book describes the biochemical mechanisms associated with dysregulation of proteases and the resulting pathophysiological consequences. It highlights the role and regulation of different types of proteases as well as their synthetic and endogenous inhibitors. The role of proteases was initially thought to be limited to general metabolic digestion. However, ... Leer más

    $143.99 USD