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1 - 12 de 12 resultados para “alexia iasonos”
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  • Handbook of Methods for Designing, Monitoring, and Analyzing Dose-Finding Trials

    Edición de John O'Quigley, Alexia Iasonos, Björn Bornkamp ...
    Series series Chapman & Hall/CRC Handbooks of Modern Statistical Methods
    Handbook of Methods for Designing, Monitoring, and Analyzing Dose-Finding Trials gives a thorough presentation of state-of-the-art methods for early phase clinical trials. The methodology of clinical trials has advanced greatly over the last 20 years and, arguably, nowhere greater than that of early phase studies. The need to accelerate drug development in a rapidly evolving context of targeted ... Leer más

    $110.99 USD

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  • Statistics Explained

    An Introductory Guide for Life Scientists

    de Steve McKillup ...
    An understanding of statistics and experimental design is essential for life science studies, but many students lack a mathematical background and some even dread taking an introductory statistics course. Using a refreshingly clear and encouraging reader-friendly approach, this book helps students understand how to choose, carry out, interpret and report the results of complex statistical analyses ... Leer más

    $43.99 USD

  • Nonclinical Statistics for Pharmaceutical and Biotechnology Industries

    de Max Kuhn, Ian Peers, Stan Altan ...
    Series series Mathematics and Statistics (R0)
    This book serves as a reference text for regulatory, industry and academic statisticians and also a handy manual for entry level Statisticians. Additionally it aims to stimulate academic interest in the field of Nonclinical Statistics and promote this as an important discipline in its own right. This text brings together for the first time in a single volume a comprehensive survey of methods ... Leer más

    $170.99 USD

  • Statistics in Food Science and Nutrition

    de Are Hugo Pripp ...
    Series series Chemistry and Material Science (R0)
    Many statistical innovations are linked to applications in food science. For example, the student t-test (a statistical method) was developed to monitor the quality of stout at the Guinness Brewery and multivariate statistical methods are applied widely in the spectroscopic analysis of foods. Nevertheless, statistical methods are most often associated with engineering, mathematics, and the medical ... Leer más

    $62.99 USD

  • Introduction to Population Pharmacokinetic / Pharmacodynamic Analysis with Nonlinear Mixed Effects Models

    de Joel S. Owen, Jill Fiedler-Kelly ...
    This book provides a user-friendly, hands-on introduction to the Nonlinear Mixed Effects Modeling (NONMEM) system, the most powerful tool for pharmacokinetic / pharmacodynamic analysis.• Introduces requisite background to using Nonlinear Mixed Effects Modeling (NONMEM), covering data requirements, model building and evaluation, and quality control aspects• Provides examples of nonlinear modeling ... Leer más

    $102.00 USD

  • Biostatistics with R

    An Introduction to Statistics Through Biological Data

    de Babak Shahbaba ...
    Series series Mathematics and Statistics (R0)
    Biostatistics with R is designed around the dynamic interplay among statistical methods, their applications in biology, and their implementation. The book explains basic statistical concepts with a simple yet rigorous language. The development of ideas is in the context of real applied problems, for which step-by-step instructions for using R and R-Commander are provided. Topics include data ... Leer más

    $80.99 USD

  • Bayesian Designs for Phase I-II Clinical Trials

    de Ying Yuan, Hoang Q. Nguyen, Peter F. Thall ...
    Series series Chapman & Hall/CRC Biostatistics Series
    Reliably optimizing a new treatment in humans is a critical first step in clinical evaluation since choosing a suboptimal dose or schedule may lead to failure in later trials. At the same time, if promising preclinical results do not translate into a real treatment advance, it is important to determine this quickly and terminate the clinical evaluation process to avoid wasting resources.Bayesian ... Leer más

    $64.99 USD

  • Benefit-Risk Assessment Methods in Medical Product Development

    Bridging Qualitative and Quantitative Assessments

    Edición de Qi Jiang, Weili He ...
    Series series Chapman & Hall/CRC Biostatistics Series
    Guides You on the Development and Implementation of B–R EvaluationsBenefit–Risk Assessment Methods in Medical Product Development: Bridging Qualitative and Quantitative Assessments provides general guidance and case studies to aid practitioners in selecting specific benefit–risk (B–R) frameworks and quantitative methods. Leading experts from industry, regulatory agencies, and academia present ... Leer más

    $72.99 USD

  • Practical Considerations for Adaptive Trial Design and Implementation

    Edición de Weili He, Olga M. Kuznetsova, José Pinheiro ...
    Series series Mathematics and Statistics (R0)
    This edited volume is a definitive text on adaptive clinical trial designs from creation and customization to utilization. As this book covers the full spectrum of topics involved in the adaptive designs arena, it will serve as a valuable reference for researchers working in industry, government and academia. The target audience is anyone involved in the planning and execution of clinical trials, ... Leer más

    $170.99 USD

  • Repeated Measures Design with Generalized Linear Mixed Models for Randomized Controlled Trials

    de Toshiro Tango ...
    Series series Chapman & Hall/CRC Biostatistics Series
    Repeated Measures Design with Generalized Linear Mixed Models for Randomized Controlled Trials is the first book focused on the application of generalized linear mixed models and its related models in the statistical design and analysis of repeated measures from randomized controlled trials. The author introduces a new repeated measures design called S:T design combined with mixed models as a ... Leer más

    $72.99 USD

  • Quick Guide to Good Clinical Practice

    How to Meet International Quality Standard in Clinical Research

    de Cemal Cingi, Nuray Bayar Muluk ...
    Series series Medicine (R0)
    This brand-new book offers a reference guide to understanding and applying the rules for properly conducting clinical trials to meet the international quality standard – Good Clinical Practice – provided by the International Conference on Harmonization (ICH).The work offers an updated perspective on the clinical research landscape within the context of the clinical trial regulatory frameworks in ... Leer más

    $89.99 USD

  • Advances in Statistical Bioinformatics

    Models and Integrative Inference for High-Throughput Data

    Edición de Kim-Anh Do, Zhaohui Steve Qin, Marina Vannucci ...
    Providing genome-informed personalized treatment is a goal of modern medicine. Identifying new translational targets in nucleic acid characterizations is an important step toward that goal. The information tsunami produced by such genome-scale investigations is stimulating parallel developments in statistical methodology and inference, analytical frameworks, and computational tools. Within the ... Leer más

    $164.99 USD