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    Series series Biomedical and Life Sciences (R0)
    Arterial stiffness is an emerging risk factor with important implications for cardiovascular disease risk. Herein, we concisely summarize the physiological and pathophysiological aspects of arterial stiffening, and highlight the importance of increased arterial stiffness for future cardiovascular events. Factors contributing to increased arterial stiffness such as advancing age, obesity, race, sex ... Leer más

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  • microRNA: Medical Evidence

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    Series series Biomedical and Life Sciences (R0)
    This volume explores microRNA function in a wide array of human disorders, providing a clinical basis for precision medicine and personalized therapies using these molecules. The twenty-one chapters, all authored by internationally-renowned experts, open with an introduction contextualizing microRNA manipulation within today’s initiatives towards precision medicine. The following chapters explore ... Leer más

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  • Platelets in Thrombotic and Non-Thrombotic Disorders

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    Series series Biomedical and Life Sciences (R0)
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  • microRNA: Basic Science

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    Edición de Gaetano Santulli ...
    Series series Biomedical and Life Sciences (R0)
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  • Proteinuria: Basic Mechanisms, Pathophysiology and Clinical Relevance

    Edición de Judith Blaine ...
    Series series Biomedical and Life Sciences (R0)
    Recent work has begun to elucidate at the molecular level how albumin is handled by the kidney and how albuminuria develops in various proteinuric diseases including minimal change disease and focal segmental glomerulosclerosis. This volume provides a comprehensive overview of the renal handling of albumin – from basic mechanisms to the pathophysiology of proteinuric diseases. In describing the ... Leer más

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  • Biology of Vascular Smooth Muscle: Vasoconstriction and Dilatation

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    This book provides a concise yet comprehensive review of the morphological, biochemical, electrical, mechanical, and metabolic properties of vascular smooth muscle, the regulation of vascular activities and the intracellular signaling involved. It particularly focuses on recently identified vasoactive agents, enzymes and transduction mechanisms. It also discusses the latest findings in the ... Leer más

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  • Molecular and Cellular Mechanobiology

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    This book will cover the cutting-edge developments in molecular and cellular mechanobiology to date. Readers will have a clear understanding of mechanobiology at the molecular and cellular levels, encompassing the mechanosensors, transducers, and transcription. An integrative approach across different scales from molecular sensing to mechanotransduction and gene modulation for physiological ... Leer más

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