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  • SCF and APC E3 Ubiquitin Ligases in Tumorigenesis

    Series series Biomedical and Life Sciences (R0)
    This SpringerBrief explores the physiological roles of Skp1-Cullin1-F-box Complex (SCF) and Anaphase Promoting Complex (APC) in normal cells and in tumor formation. These two related, multi-subunit E3 ubiquitin ligase enzymes, APC and SCF are thought to be the major driving forces governing proper cell cycle progression. Defective cell cycle regulation leads to genomic instability and ultimately, ... Read more

    $49.49 USD

  • Cullin-RING Ligases and Protein Neddylation

    Biology and Therapeutics

    Edited by Yi Sun, Wenyi Wei, Jianping Jin ...
    Series series Biomedical and Life Sciences (R0)
    This book summarizes all the important aspects of CRLs (Cullin-RING E3 Ubiquitin Ligases), while providing details of mechanistic specifics that go beyond protein ubiquitination and neddylation. Ubiquitin ligases, including the CRLs, which are activated by neddylation, play an important role in diverse biological processes and are involved in various human diseases, particularly cancer. The book ... Read more

    $143.09 USD

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    Notes of a Biology Watcher

    by Lewis Thomas ...
    Elegant, suggestive, and clarifying, Lewis Thomas's profoundly humane vision explores the world around us and examines the complex interdependence of all things. Extending beyond the usual limitations of biological science and into a vast and wondrous world of hidden relationships, this provocative book explores in personal, poetic essays to topics such as computers, germs, language, music, death, ... Read more

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  • The Dental Pulp

    Biology, Pathology, and Regenerative Therapies

    Edited by Michel Goldberg ...
    Series series Medicine (R0)
    This book provides a detailed update on our knowledge of dental pulp and regenerative approaches to therapy. It is divided into three parts. The pulp components are first described, covering pulp cells, extracellular matrix, vascularization and innervation as well as pulp development and aging. The second part is devoted to pulp pathology and includes descriptions of the differences between ... Read more

    $107.09 USD

  • Biopatent Law: Patent Strategies and Patent Management

    Series series Biomedical and Life Sciences (R0)
    Patents protecting biotechnological invention are becoming ever more important. Because biotechnology has many differences with respect to other technologies, lessons learned in other fields of technology cannot simply be transferred to adopt a suitable strategy for dealing with biotechnology inventions.In this volume, general aspects of biopatent law will be discussed. This involves questions of ... Read more

    $76.49 USD

  • Translation and Its Regulation in Cancer Biology and Medicine

    Edited by Armen Parsyan ...
    Series series Biomedical and Life Sciences (R0)
    This book, for the first time, comprehensively assembles and analyzes a large body of information on the role of the fundamental mechanism of the protein biosynthesis pathway, translation, in cancer biology. It systematically explores the function of the translation machinery and its regulation, including cell signaling, in the development, maintenance and progression of human cancer. The work ... Read more

    $143.09 USD

  • Biochemical Basis and Therapeutic Implications of Angiogenesis

    Series series Biomedical and Life Sciences (R0)
    Angiogenesis is a highly complex phenomenon where new blood vessels are formed for the supply of oxygen and nutrients in different organs of the body. It plays a critical role in both physiological processes such as growth and development as well as pathological processes including cancer and different types of tumors. Angiogenesis is also essential for the regeneration and survival of cells in ... Read more

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  • Plant Responses to Air Pollution

    Series series Biomedical and Life Sciences (R0)
    This book focuses upon air pollution, types of air pollutants and their impact on plant physiological and biochemical systems. The book begins with a brief background on air pollution and continues with a discussion on different types, effects, and solutions to the pollution. The chapters that follow, explore the different effects of pollution on chloroplasts, respiration, biochemistry and ... Read more

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  • microRNA: Medical Evidence

    From Molecular Biology to Clinical Practice

    Edited by Gaetano Santulli ...
    Series series Biomedical and Life Sciences (R0)
    This volume explores microRNA function in a wide array of human disorders, providing a clinical basis for precision medicine and personalized therapies using these molecules. The twenty-one chapters, all authored by internationally-renowned experts, open with an introduction contextualizing microRNA manipulation within today’s initiatives towards precision medicine. The following chapters explore ... Read more

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  • Oral Delivery of Macromolecular Drugs

    Barriers, Strategies and Future Trends

    Series series Biomedical and Life Sciences (R0)
    Recent and rapid progress in the field of biotechnology has resulted in an increasing number of novel macromolecular drugs with great promise for further advanced research and clinical application. However, the delivery of these macromolecular drugs by routes other than the parenteral route is difficult. The pipeline of macromolecular drugs derived from biotechnology presents a challenging ... Read more

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  • Death Receptors and Cognate Ligands in Cancer

    Edited by Holger Kalthoff ...
    Series series Biomedical and Life Sciences (R0)
    Death receptors play a central role in directing apoptosis in mammalian cells. This process of active cell death is important for a number of biological processes, e.g. for the regulation of the immune system. Death receptors are cell surface receptors that transmit apoptotic signals initiated by corresponding death ligands. Many complex signaling pathways are activated and apoptosis is the final ... Read more

    $188.09 USD