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  • Histone Recognition

    Edited by Ming-Ming Zhou ...
    Series series Biomedical and Life Sciences (R0)
    This book provides a timely review of the role of histone modifications in epigenetic control of gene expression. Topics covered include: basic mechanisms of molecular recognition of histone post-translational modification (PTMs); combinatorial readout of histone PTMs by tandem epigenome reader domains; genome-wide profiling of histone PTM interactions; small molecule modulation of histone PTM ... Read more

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  • Genomics and Personalized Medicine

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    Series series What Everyone Needs To Know®
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  • JIMD Reports, Volume 32

    Series series Biomedical and Life Sciences (R0)
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  • Nutrition and Genomics

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    Nutrigenomics is the rapidly developing field of science that studies nutrient-gene interaction. This field has broad implications for understanding the interaction of human genomics and nutrition, but can also have very specific implications for individual dietary recommendations in light of personal genetics. Predicted applications for nutrigenomics include genomics-based dietary guidelines and ... Read more

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  • Carbohydrate and Glycoprotein Metabolism; Maternal Phenylketonuria

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    G protein-coupled receptors (GPCRs) are heptahelical transmembrane receptors that convert extra-cellular stimuli into intra-cellular signaling, and ultimately into biological responses. Since GPCRs are natural targets for approximately 40% of all modern medicines, it is not surprising that they have been the subject of intense research. Notwithstanding the amount of data generated over the years, ... Read more

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  • Cardiovascular Pharmacogenetics

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    Series series Biomedical and Life Sciences (R0)
    The Human Genome Project was sold to the general public largely on the basis that a complete picture of the structure of human DNA would lead to new and better medicines. These medicines would be better because they would be tailored to individual patients, maximising the chances of a therapeutic response and mi nimising the risks of an adverse event. Taking the idea further, pundits have pre ... Read more

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    Series series Medicine (R0)
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    Series series Springer Nature Proceedings excluding Computer Science
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