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  • The Role of Glycosylation in Health and Disease

    Series series Biomedical and Life Sciences (R0)
    Glycobiology is an emerging field of studying glycans (sugars) and glycoconjugates that are essentially involved in almost all biological processes, from fine-tuning glycoprotein function to protein-protein interactions, signaling, immune response, host-pathogen interactions, etc. However, due to structural complexity of glycans and analytical challenges this exciting field was lagging behind ... Read more

    $188.09 USD

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  • Resistance of Cancer Cells to CTL-Mediated Immunotherapy

    Series series Biomedical and Life Sciences (R0)
    This comprehensive volume explores the latest research on the mechanisms of resistance in cancer cells to CTL-mediated immunotherapy. Chapter topics discuss cell-mediated immunity as the result of cytotoxic T-lymphocytes (CTL) directed specifically against cancer cells. In addition, the volume reviews how CTL mediate the cytotoxic activity, in large part, by the indication of apoptosis; hence, ... Read more

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  • The Epigenetics of Autoimmunity

    Edited by Rongxin Zhang ...
    Series Book 5 - Translational Epigenetics
    The Epigenetics of Autoimmunity covers a topic directly related to translational epigenetics. Via epigenetic mechanisms, a number of internal and external environmental risk factors, including smoking, nutrition, viral infection and the exposure to chemicals, could exert their influence on the pathogenesis of autoimmune diseases. Such factors could impact the epigenetic mechanisms, which, in turn, ... Read more

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  • Pharmacogenomics of Human Drug Transporters

    Clinical Impacts

    Sets the foundation for safer, more effective drug therapiesWith this book as their guide, readers will discover how to apply our current understanding of the pharmacogenomics of drug transporters to advance their own drug discovery and development efforts. In particular, the book explains how new findings in the field now enable researchers to more accurately predict drug interactions and adverse ... Read more

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  • Cancer Stem Cells

    Cancer Stem Cells covers a wide range of topics in cancer stem cell biology, including the functional characteristics of cancer stem cells and how they're generated, where they are localized, the means by which cancer stem cells can be targeted, and how cancer stem cells can be reprogrammed back to normal tissue stem cells. Each chapter begins with a brief historical note and concept summary, ... Read more

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  • Glioblastoma:

    Molecular Mechanisms of Pathogenesis and Current Therapeutic Strategies

    Edited by Swapan K. Ray ...
    Series series Biomedical and Life Sciences (R0)
    Glioblastoma is the most malignant brain tumor that still remains incurable. It is such a deadly disease that patients do not survive more than a few months after diagnosis. Our understanding of the histopathology and molecular mechanisms of formation of glioblastoma is rapidly advancing so as to provide us clues for devising rational therapeutic strategies for treatment of this malignancy. It is ... Read more

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  • Transportome Malfunction in the Cancer Spectrum

    Ion Transport in Tumor Biology

    Series series Biomedical and Life Sciences (R0)
    This is the first of three volumes in the "Ion Channels & Transporters in Tumor Biology" collection, which discusses the function of ion transport proteins in cellular and systemic homeostasis. The authors highlight the role of the so-called transportome, which is defined by the entirety of ion transporters and ion channels. Thereby, readers will get a better understanding of the impact ... Read more

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  • Cancer Research: An Interdisciplinary Approach

    Edited by Nima Rezaei ...
    Series series Biomedical and Life Sciences (R0)
    Cancer is a major public health concern and one of the leading causes of death. There is no simple solution for this complex disease, therefore interdisciplinary approaches might help to find solutions to many unanswered questions and challenges about cancer. The rapid flow of interdisciplinary research in cancer during recent years has increased our understanding of the nature of cancers. Such ... Read more

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  • Cancer Stem Cells: Emerging Concepts and Future Perspectives in Translational Oncology

    Edited by Sadegh Babashah ...
    Series series Biomedical and Life Sciences (R0)
    The concept of cancer stem cells has great clinical implications. This is due to the fact that small subpopulations of these cells have been identified in a variety of neoplastic conditions ranging from solid tumors to liquid malignancies. Although there are some huge gaps in our current understanding of the role played by cancer stem cells in cancer biology, a growing body of evidence provides ... Read more

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  • New Frontiers: Extracellular Vesicles

    Series series Biomedical and Life Sciences (R0)
    The field of extracellular vesicles (EVs) has progressed immensely in recent times with evidences highlighting their importance in physiology and pathology. This book entails extensive reflective literature on many subtypes of EVs including exosomes, exomeres, ectosomes, apoptotic vesicles, bacterial EVs and fungal EVs.The book further discusses the biogenesis and secretion of these EVs, detailing ... Read more

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  • New Advances on Disease Biomarkers and Molecular Targets in Biomedicine

    Rising occurrences of various diseases and epidemics have pressurized the already-burdened health system across the globe, and this imposes an unprecedented challenge on our current research in identifying disease-specific biomarkers and molecular targets, in particular for cancers, neurological disorders and unexplained infertility. Despite decades of efforts in deciphering the fundamental ... Read more

    $116.09 USD

  • Epigenetics in Cardiac Disease

    Series series Biomedical and Life Sciences (R0)
    This book describes important advances in our understanding of how environmental conditions affect cardiac gene expression through epigenetic mechanisms. Further, it discusses the roles of chromatin modifications (in particular DNA methylation and histone modifications) and of chromatin regulators in the context of cardiac diseases. The book provides readers with an overview of our current ... Read more

    $143.09 USD