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  • Translational Bioinformatics and Its Application

    Series series Biomedical and Life Sciences (R0)
    This book offers a detailed overview of translational bioinformatics together with real-case applications. Translational bioinformatics integrates the areas of basic bioinformatics, clinical informatics, statistical genetics and informatics in order to further our understanding of the molecular basis of diseases. By analyzing voluminous amounts of molecular and clinical data, it also provides ... Read more

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    Series series Biomedical and Life Sciences (R0)
    The introduction of Next Generation Sequencing (NGS) technologies resulted in a major transformation in the way scientists extract genetic information from biological systems, revealing limitless insight about the genome, transcriptome and epigenome of any species. However, with NGS, came its own challenges that require continuous development in the sequencing technologies and bioinformatics ... Read more

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  • Basics of Bioinformatics

    Lecture Notes of the Graduate Summer School on Bioinformatics of China

    Series series Computer Science (R0)
    This book outlines 11 courses and 15 research topics in bioinformatics, based on curriculums and talks in a graduate summer school on bioinformatics that was held in Tsinghua University. The courses include: Basics for Bioinformatics, Basic Statistics for Bioinformatics, Topics in Computational Genomics, Statistical Methods in Bioinformatics, Algorithms in Computational Biology, Multivariate ... Read more

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  • BetaSys

    Systems Biology of Regulated Exocytosis in Pancreatic ß-Cells

    Series series Biomedical and Life Sciences (R0)
    BetaSys uses the example of regulated exocytosis in pancreatic β-cells, and its relevance to diabetes, to illustrate the major concepts of systems biology, its methods and applications. ... Read more

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  • Longevity Genes

    A Blueprint for Aging

    Edited by Gil Atzmon, PhD ...
    Series series Biomedical and Life Sciences (R0)
    The release of the complete version of the human genome sequence in 2003 has paved the way for defining gene function and genetic background for phenotypic variation in humans and allowed us to study the aging process in a new light. This new volume results from that research and focuses on the genetic and epigenetic process of aging. While the interpretation of the genome data is still in its ... Read more

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  • Weighted Network Analysis

    Applications in Genomics and Systems Biology

    by Steve Horvath ...
    Series series Biomedical and Life Sciences (R0)
    High-throughput measurements of gene expression and genetic marker data facilitate systems biologic and systems genetic data analysis strategies. Gene co-expression networks have been used to study a variety of biological systems, bridging the gap from individual genes to biologically or clinically important emergent phenotypes. ... Read more

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  • Soft Computing for Biological Systems

    Series series Biomedical and Life Sciences (R0)
    This book explains how the biological systems and their functions are driven by genetic information stored in the DNA, and their expression driven by different factors. The soft computing approach recognizes the different patterns in DNA sequence and try to assign the biological relevance with available information.The book also focuses on using the soft-computing approach to predict protein ... Read more

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  • Gene Network Inference

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    Edited by Alberto Fuente ...
    Series series Biomedical and Life Sciences (R0)
    This book presents recent methods for Systems Genetics (SG) data analysis, applying them to a suite of simulated SG benchmark datasets. Each of the chapter authors received the same datasets to evaluate the performance of their method to better understand which algorithms are most useful for obtaining reliable models from SG datasets. The knowledge gained from this benchmarking study will ... Read more

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  • Discriminative Pattern Discovery on Biological Networks

    Series series Computer Science (R0)
    This work provides a review of biological networks as a model for analysis, presenting and discussing a number of illuminating analyses. Biological networks are an effective model for providing insights about biological mechanisms. Networks with different characteristics are employed for representing different scenarios. This powerful model allows analysts to perform many kinds of analyses which ... Read more

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  • MicroRNA Cancer Regulation

    Advanced Concepts, Bioinformatics and Systems Biology Tools

    Series series Biomedical and Life Sciences (R0)
    This edited reflects the current state of knowledge about the role of microRNAs in the formation and progression of solid tumours. The main focus lies on computational methods and applications, together with cutting edge experimental techniques that are used to approach all aspects of microRNA regulation in cancer. We are sure that the emergence of high-throughput quantitative techniques will make ... Read more

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  • Cognitive Science and Artificial Intelligence

    Advances and Applications

    Series series Engineering (R0)
    This book presents interdisciplinary research on cognition, mind and behavior from an information processing perspective. It includes chapters on Artificial Intelligence, Decision Support Systems, Machine Learning, Data Mining and Support Vector Machines, chiefly with regard to the data obtained and analyzed in Medical Informatics, Bioinformatics and related disciplines. The book reflects the ... Read more

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  • Comparative Genomics

    15th International Workshop, RECOMB CG 2017, Barcelona, Spain, October 4-6, 2017, Proceedings

    Edited by Joao Meidanis, Luay Nakhleh ...
    Series series Springer Nature Proceedings Computer Science
    This book constitutes the proceedings of the 15th International Workshop Comparative Genomics, RECOMB-CG 2017, held in Barcelona, Spain, in October 2017. The 16 full papers presented were carefully reviewed and selected from 32 submissions. The papers report original research in all areas of Comparative Genomics. ... Read more

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