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1-12 sur 12 résultats pour « pranela rameshwar »
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  • The Stem Cell Microenvironment and Its Role in Regenerative Medicine and Cancer Pathogenesis

    Modifié par Cristian Pablo Pennisi, Mayuri Sinha Prasad, Pranela Rameshwar ...
    How stem cells behave is very much a factor of their local microenvironment, also known as the stem cell niche. Physical, chemical, or electrical signals from the neighboring cells or biochemical signals from distant cells are crucial in the cell fate decision process. A major challenge of tissue engineering is to mimic the natural cell environment by designing very sophisticated scaffolds able ... En savoir plus

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  • Stepwise Culture of Human Adult Stem Cells

    Modifié par Pranela Rameshwar ...
    Collections series River Publishers Series in Biotechnology and Medical Research
    This volume on stepwise techniques to culture adult human stem cells begins with the basic methods to culture adult stem cells followed by related methods to supplement stem cell culture. This and future volumes of techniques will allow laboratories across scientific entities – academic and commercial – to adapt the described methods for similar methods with cells from other species. The ... En savoir plus

    $183.99 CAD

  • Exosomes, Stem Cells and MicroRNA

    Aging, Cancer and Age Related Disorders

    Modifié par Karl L. Mettinger, Pranela Rameshwar, Vinod Kumar ...
    Collections series Biomedical and Life Sciences (R0)
    This volume provides insight into the pivotal roles of stem cells, exosomes and other microvesicles in biofunction and molecular mechanisms and their therapeutic potential in translational nanomedicine. It further highlights evidence from recent studies as to how stem cell derived exosomes and microRNAs may restore and maintain tissue homeostasis, enable cells to recover critical cellular ... En savoir plus

    $218.99 CAD

  • MicroRNA in Development and in the Progression of Cancer

    Modifié par Shree Ram Singh, Pranela Rameshwar ...
    Collections series Biomedical and Life Sciences (R0)
    miRNAs are a class of endogenous, small non-protein coding RNA molecules (~ 22 nucleotides) which are novel post-transcriptional regulators of gene expression. Since we have hundreds of miRNAs, the major challenge is now to understand their specific biological function. In fact the experimental evidence suggests that signaling pathways could be ideal candidates for miRNA-mediated regulation. ... En savoir plus

    $179.99 CAD

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  • Epigenetics in Cardiac Disease

    Modifié par Johannes Backs, Timothy A. McKinsey ...
    Collections series Biomedical and Life Sciences (R0)
    This book describes important advances in our understanding of how environmental conditions affect cardiac gene expression through epigenetic mechanisms. Further, it discusses the roles of chromatin modifications (in particular DNA methylation and histone modifications) and of chromatin regulators in the context of cardiac diseases. The book provides readers with an overview of our current ... En savoir plus

    $179.99 CAD

  • Resistance of Cancer Cells to CTL-Mediated Immunotherapy

    Modifié par Benjamin Bonavida, Salem Chouaib ...
    Collections series Biomedical and Life Sciences (R0)
    This comprehensive volume explores the latest research on the mechanisms of resistance in cancer cells to CTL-mediated immunotherapy. Chapter topics discuss cell-mediated immunity as the result of cytotoxic T-lymphocytes (CTL) directed specifically against cancer cells. In addition, the volume reviews how CTL mediate the cytotoxic activity, in large part, by the indication of apoptosis; hence, ... En savoir plus

    $115.99 CAD

  • Cancer Stem Cells

    par Vinagolu K. Rajasekhar ...
    Cancer Stem Cells covers a wide range of topics in cancer stem cell biology, including the functional characteristics of cancer stem cells and how they're generated, where they are localized, the means by which cancer stem cells can be targeted, and how cancer stem cells can be reprogrammed back to normal tissue stem cells. Each chapter begins with a brief historical note and concept summary, ... En savoir plus

    $157.99 CAD

  • Pharmacogenomics of Human Drug Transporters

    Clinical Impacts

    par Toshihisa Ishikawa, Richard B. Kim, Jörg König ...
    Sets the foundation for safer, more effective drug therapiesWith this book as their guide, readers will discover how to apply our current understanding of the pharmacogenomics of drug transporters to advance their own drug discovery and development efforts. In particular, the book explains how new findings in the field now enable researchers to more accurately predict drug interactions and adverse ... En savoir plus

    $191.99 CAD

  • Advances in Biology and Therapy of Multiple Myeloma

    Volume 1: Basic Science

    Modifié par Nikhil C. Munshi, Kenneth C. Anderson ...
    Collections series Biomedical and Life Sciences (R0)
    Despite the advances in conventional, novel agent and high dose chemotherapy multiple myeloma (MM) remains incurable. In order to overcome resistance to current therapies and improve patient outcome, novel biologically-based treatment approaches are being developed. Current translational research in MM focusing on the development of molecularly-based combination therapies has great promise to ... En savoir plus

    $179.99 CAD

  • The Epigenetics of Autoimmunity

    Modifié par Rongxin Zhang ...
    Collections Livre 5 - Translational Epigenetics
    The Epigenetics of Autoimmunity covers a topic directly related to translational epigenetics. Via epigenetic mechanisms, a number of internal and external environmental risk factors, including smoking, nutrition, viral infection and the exposure to chemicals, could exert their influence on the pathogenesis of autoimmune diseases. Such factors could impact the epigenetic mechanisms, which, in turn, ... En savoir plus

    $163.99 CAD

  • The Role of Glycosylation in Health and Disease

    Modifié par Gordan Lauc, Irena Trbojević-Akmačić ...
    Collections series Biomedical and Life Sciences (R0)
    Glycobiology is an emerging field of studying glycans (sugars) and glycoconjugates that are essentially involved in almost all biological processes, from fine-tuning glycoprotein function to protein-protein interactions, signaling, immune response, host-pathogen interactions, etc. However, due to structural complexity of glycans and analytical challenges this exciting field was lagging behind ... En savoir plus

    $256.99 CAD

  • Emerging Concepts Targeting Immune Checkpoints in Cancer and Autoimmunity

    Modifié par Akihiko Yoshimura ...
    Collections series Biomedical and Life Sciences (R0)
    This volume reviews the current state of research on immune checkpoints and offers novel concepts. It discusses the two most important immune checkpoints: T lymphocyte-associated antigen-4 (CTLA-4) and programmed cell death-1 (PD-1). It shows that antagonistic antibodies against these two molecules are highly effective in the treatment of various cancers and that PD-1 and CTLA-4 have been linked ... En savoir plus

    $218.99 CAD