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  • The Pineal Organ, Its Hormone Melatonin, and the Photoneuroendocrine System

    Series series Medicine (R0)
    Provides comprehensive, updated information on the structure, and cell and molecular biology of the vertebrate pineal organ, which is the source of the "timing hormone" melatonin. ... Read more

    $115.99 CAD

  • The Neuropathology of Huntington’s Disease: Classical Findings, Recent Developments and Correlation to Functional Neuroanatomy

    Series series Biomedical and Life Sciences (R0)
    This monograph describes the progress in neuropathological HD research made during the last century, the neuropathological hallmarks of HD and their pathogenic relevance. Starting with the initial descriptions of the progressive degeneration of the striatum as one of the key events in HD, the worldwide practiced Vonsattel HD grading system of striatal neurodegeneration will be outlined. ... Read more

    $115.99 CAD

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  • Acute Neuronal Injury

    The Role of Excitotoxic Programmed Cell Death Mechanisms

    Edited by Denson G. Fujikawa ...
    Series series Biomedical and Life Sciences (R0)
    Dr. Denson Fujikawa is an Adjunct Professor of Neurology at the David Geffen School of Medicine at UCLA, a member of the Brain Research Institute at UCLA and a Staff Neurologist at the Department of Veterans Affairs Greater Los Angeles Healthcare System. His interest in mechanisms of nerve cell death in the brain began during a two-year epilepsy research fellowship with Dr. Claude Wasterlain, from ... Read more

    $281.99 CAD

  • Oxygen Homeostasis and Its Dynamics

    Series series Medicine (R0)
    This first volume in a projected series contains the proceedings of the first of the Keio University International Symposia for Life Sciences and Medicine under the sponsorship of the Keio University Medical Science Fund. As stated in the address by the President of Keio University at the opening of the 1996 symposium, the fund of Dr. Mitsunada Sakaguchi. The Keio was established by the generous ... Read more

    $64.99 CAD

  • Behavioral Neurobiology of Huntington's Disease and Parkinson's Disease

    Series series Biomedical and Life Sciences (R0)
    Motor dysfunction and cognitive impairment are major symptoms in both Huntington’s Disease (HD) and Parkinson’s Disease (PD). A breakthrough in HD research was the identification of the gene that causes this devastating monogenetic illness. Similarly, several genes were found to cause familial forms of PD. With their identification, a plethora of genetic animal models has been generated and has ... Read more

    $115.99 CAD

  • The Human Hippocampus

    Functional Anatomy, Vascularization and Serial Sections with MRI

    Series series Medicine (R0)
    This new edition, like previous ones, offers a precise description of the anatomy of the human hippocampus based upon neurosurgical progress and the wealth of medical imaging methods available. The first part describes the fine structures of the hippocampus and is illustrated with new original figures. A survey is then provided of current concepts explaining the functions of the hippocampus, and ... Read more

    $141.99 CAD

  • Astrocytes in (Patho)Physiology of the Nervous System

    Series series Biomedical and Life Sciences (R0)
    Astrocytes were the original neuroglia that Ramón y Cajal visualized in 1913 using a gold sublimate stain. This stain targeted intermediate filaments that we now know consist mainly of glial fibrillary acidic protein, a protein used today as an astrocytic marker. Cajal described the morphological diversity of these cells with some ast- cytes surrounding neurons, while the others are intimately ... Read more

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  • Cardiovascular and Musculoskeletal Systems

    Series series Medicine (R0)
    This is the ninth volume in a series dealing with induced lesions in laboratory animals. The information on pathology and toxicology documented in the series is an aid to scientific institutions, industry and government agencies charged with the safety testing of food, drugs and chemicals. ... Read more

    $115.99 CAD

  • Müller Cells in the Healthy and Diseased Retina

    Series series Biomedical and Life Sciences (R0)
    Müller cells may be used in the future for novel therapeutic strategies to protect neurons against apoptosis (for example, somatic gene therapy), or to differentiate retinal neurons from Müller/stem cells. Meanwhile, a proper understanding of the gliotic responses of Müller cells in the diseased retina, and of their protective vs. detrimental effects, is essential for the development of efficient ... Read more

    $307.99 CAD

  • Advances in Down Syndrome Research

    Edited by Gert Lubec ...
    Series series Medicine (R0)
    "Advances in Down Syndrome Research” represents updated research in several areas of Down Syndrome (DS). A new promising animal model of DS is reported and this opens new opportunities to study pathomechanisms and pharmacological approaches as it is more than difficult to carry out studies in humans and the clinical features are highly variable. In terms of biology, cell cycle and stem cell ... Read more

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  • Folding for the Synapse

    Series series Biomedical and Life Sciences (R0)
    Folding for the Synapse addresses the current view on how protein folding and misfolding, controlled by molecular chaperones, contribute to synapse function and dysfunction. Molecular chaperones have been studied in relation to de novo protein folding, but there is increasing awareness that chaperone function is required for the regulation of protein dynamics when functioning physiologically as an ... Read more

    $256.99 CAD

  • Stem Cells and Cancer Stem Cells, Volume 5

    Therapeutic Applications in Disease and Injury

    Edited by M.A. Hayat ...
    Series series Biomedical and Life Sciences (R0)
    It is pointed out that a cancer stem cell is a type within a tumor that possesses the capacity of self-renewal and can give rise to the heterogeneous lineages of cancer cells, which comprise the tumor. It is emphasized that a unique feature of cancer stem cells is that, although conventional chemotherapy kills most cells in a tumor, cancer stem cells remain intact. Vast applications of the ... Read more

    $256.99 CAD