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  • New Approaches to Drug Discovery

    Series series Biomedical and Life Sciences (R0)
    This volume gives an overview of state of the art technologies and future developments in the field of preclinical pharmaceutical research. A balanced mix of experts from academia and industry give insight in selected new developments in the drug discovery pathway. The topics cover the different parts of the drug discovery process, starting with new developments in the target identification and ... Read more

    $256.99 CAD

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  • Cancer Drug Design and Discovery

    Edited by Stephen Neidle ...
    The ultimate source of information on the design of new anticancer agents, emphasizing small molecules, this newest work covers recent notable successes resulting from the human genome and cancer genomics projects. These advances have provided information on targets involved in specific cancers that are leading to effective medicines for at least some of the common solid tumors. Unique sections ... Read more

    $97.59 CAD

  • Imaging Mass Spectrometry

    Protocols for Mass Microscopy

    Edited by Mitsutoshi Setou ...
    Series series Biomedical and Life Sciences (R0)
    Addressing the widespread need for a practical guide to imaging mass spectrometry (IMS), this book presents the protocols of IMS technology. As that technology expands, research groups around the world continue its development. Pharmaceutical companies are using IMS for drug analyses to study pharmacokinetics and medical properties of drugs. Drug research and disease-related biomarker screening ... Read more

    $115.99 CAD

  • Synthesis and Vaccine Evaluation of the Tumor Associated Carbohydrate Antigen RM2 from Prostate Cancer

    Series series Chemistry and Material Science (R0)
    This thesis focuses on the synthesis and vaccine evaluation of the prostate tumor- associated carbohydrate antigen RM2. The author first presents the use of the [1+2+3] one-pot sequential strategy to successfully synthesise the RM2 antigen and its analogues as single stereoisomers in every glycosylation step, producing good yields and stereoselectivity. He then introduces the conjugation of the ... Read more

    $64.99 CAD

  • Arachidonate Remodeling and Inflammation

    Series series Progress in Inflammation Research
    Arachidonic acid (AA) and other 20 or 22-carbon polyunsaturated fatty acids (PUFAs) are precursors of lipid mediators of inflammation known as eicosanoids. These mediators are critical in disease processes and in regulating normal cell function. Remodeling is important in maintaining homeostasis and in regulating cell function by dictating how PUFAs are converted to lipid mediators of inflammation ... Read more

    $115.99 CAD

  • Transition Metal Complexes of Neutral eta1-Carbon Ligands

    Edited by Remi Chauvin, Yves Canac ...
    Series series Chemistry and Material Science (R0)
    Contents: Yves Canac and Remi Chauvin: Neutral eta1-carbon ligands: beyond carbon monoxide; Esteban P. Urriolabeitia: Ylide Ligands; Wolfgang Petz and Gernot Frenking: Carbodiphosphoranes and related ligands; Mareike C. Jahnke and F. Ekkehardt Hahn: Chemistry of N-Heterocyclic Carbene Ligands; Tsuyoshi Kato, Eddy Maerten, Antoine Baceiredo: Non-NHCs stable singlet carbene ligands; Victorio ... Read more

    $371.99 CAD

  • Drug Discovery in Africa

    Impacts of Genomics, Natural Products, Traditional Medicines, Insights into Medicinal Chemistry, and Technology Platforms in Pursuit of New Drugs

    Series series Chemistry and Material Science (R0)
    Drug discovery originating in Africa has the potential to provide significantly improved treatment of endemic diseases such as malaria, tuberculosis and HIV/AIDS. This book critically reviews the current status of drug discovery research and development in Africa, for diseases that are a major threat to the health of people living in Africa. Compiled by leading African and international experts, ... Read more

    $179.99 CAD

  • Adhesion G Protein-coupled Receptors

    Molecular, Physiological and Pharmacological Principles in Health and Disease

    Series series Biomedical and Life Sciences (R0)
    Latest research on Adhesion GPCRs has unearthed surprising revelations about the events that govern the signal transduction of these receptor molecules and the cellular and organ requirements for these signals. Unexpected and unprecedented findings suggest that Adhesion GPCRs constitute a group of receptors that sense mechanical stimuli and transcode them into metabotropic signals through the ... Read more

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  • Hydrogen Peroxide Metabolism in Health and Disease

    Series series Oxidative Stress and Disease
    Much of the biology of oxidative stress and oxidative signalling centres on the generation and handling of hydrogen peroxide. The overall aim for this book would be to provide an insightful and useful forum to assist with the understanding of the relevance of hydrogen peroxide generation and how this is managed in human biology. The target audience would be those who currently have an interest in ... Read more

    $104.99 CAD

  • Progress in the Chemistry of Organic Natural Products 105

    Series series Chemistry and Material Science (R0)
    The first contribution reviews the occurrence of xanthine alkaloids in the plant kingdom and the elucidation of the caffeine biosynthesis pathway, providing details of the N-methyltransferases, belonging to the motif B' methyltransferase family which catalyze three steps in the four step pathway leading from xanthosine to caffeine. The second contribution in this book provides a background on the ... Read more

    $218.99 CAD