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“shufeng zhou”

Showing 1 - 12 of 12 results for “shufeng zhou”
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  • Cytochrome P450 2D6

    Structure, Function, Regulation and Polymorphism

    by Shufeng Zhou ...
    Cytochromes are proteinsthat catalyze electron transfer reactions of well-known metabolic pathways and are classified in various superfamilies. The CYP, or P450, superfamily accounts for 90% of the oxidative metabolism of clinical drugs. One member of this superfamily, P450 2D6 (or CYP2D6), singlehandedly metabolizes about 25% of all medications in the human liver. Cytochrome P450 2D6: Structure, ... Read more

    $100.99 CAD

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  • DNA Repair in Cancer Therapy

    Molecular Targets and Clinical Applications

    Edited by Mark R. Kelley ...
    Cancer therapeutics include an ever-increasing array of tools at the disposal of clinicians in their treatment of this disease. However, cancer is a tough opponent in this battle, and current treatments, which typically include radiotherapy, chemotherapy and surgery, are not often enough to rid the patient of his or her cancer. Cancer cells can become resistant to the treatments directed at them, ... Read more

    $121.59 CAD

  • Handbook of Cell Signaling

    Series series Cell Biology
    Handbook of Cell Signaling, Three-Volume Set, 2e, is a comprehensive work covering all aspects of intracellular signal processing, including extra/intracellular membrane receptors, signal transduction, gene expression/translation, and cellular/organotypic signal responses. The second edition is an up-to-date, expanded reference with each section edited by a recognized expert in the field. Tabular ... Read more

    $472.79 CAD

  • Mitochondria and Cancer

    Edited by Keshav Singh, Leslie Costello ...
    Nearly a century of scientific research has revealed that mitochondrial dysfunction is one of the most common and consistent phenotypes of cancer cells. A number of notable differences in the mitochondria of normal and cancer cells have been described. These include differences in mitochondrial metabolic activity, molecular composition of mitochondria and mtDNA sequence, as well as in alteration ... Read more

    $179.99 CAD

  • The DNA Damage Response: Implications on Cancer Formation and Treatment

    Edited by Yosef Shiloh, Kum Kum Khanna ...
    Series series Biomedical and Life Sciences (R0)
    The ?eld of cellular responses to DNA damage has attained widespread recognition and interest in recent years commensurate with its fundamental role in the ma- tenance of genomic stability. These responses, which are essential to preventing cellular death or malignant transformation, are organized into a sophisticated s- tem designated the “DNA damage response”. This system operates in all living ... Read more

    $179.99 CAD

  • Pharmacogenomics of Human Drug Transporters

    Clinical Impacts

    Sets the foundation for safer, more effective drug therapiesWith this book as their guide, readers will discover how to apply our current understanding of the pharmacogenomics of drug transporters to advance their own drug discovery and development efforts. In particular, the book explains how new findings in the field now enable researchers to more accurately predict drug interactions and adverse ... Read more

    $191.99 CAD

  • Regulation of Carbohydrate Metabolism(1985)

    Volume I

    by Rivka Beitner ...
    First Published in 1985. A collaboration of the latest research on regulation of carbohydrate metabolism. ... Read more

    $329.99 CAD

  • DNA Repair of Cancer Stem Cells

    Series series Biomedical and Life Sciences (R0)
    The existence of ‘cancer stem cells’ (CSCs) has been a topic of heated debate for the last few years within the field of cancer biology. Their continuous characterization in a variety of solid tumors has lead to an abundance of evidence supporting their existence. CSCs are believed to be responsible for resistance against conventional treatment regimes of chemotherapy and radiation, ultimately, ... Read more

    $179.99 CAD

  • Stress-Induced Mutagenesis

    Edited by David Mittelman ...
    Series series Biomedical and Life Sciences (R0)
    The discovery of stress-induced mutagenesis has changed ideas about mutation and evolution, and revealed mutagenic programs that differ from standard spontaneous mutagenesis in rapidly proliferating cells. The stress-induced mutations occur during growth-limiting stress, and can include adaptive mutations that allow growth in the otherwise growth-limiting environment. The stress responses increase ... Read more

    $179.99 CAD

  • Nuclear Signaling Pathways and Targeting Transcription in Cancer

    Edited by Rakesh Kumar ...
    Series series Biomedical and Life Sciences (R0)
    At the moment, there is no dedicated book to summarize the roles, the significance, and potential therapeutic targeting of transcriptional factors from the perspective of signaling cascade, and thus, directly impacting the functionality of transcriptional factors in cancer. In addition, this book will offer a comprehensive basic and clinical science behind the functions of representative core ... Read more

    $179.99 CAD

  • Drug Resistance in Cancer Cells

    Edited by Kapil Mehta, Zahid H. Siddik ...
    Series series Biomedical and Life Sciences (R0)
    It was estimated that in 2008, 1,437,180 patients would receive a new cancer diagnosisand 565,650individualswould die of cancer (Jemal et al. 2008).Since the vast majority of patients dying of cancer will have had anticancer therapy, both c- ventional chemotherapy and novel targeted therapy, it can be concluded that these patients are dying with drug resistant cancer. The term multidrug resistance ... Read more

    $179.99 CAD

  • Immune Metabolism in Health and Tumor

    Edited by Bin Li, Fan Pan ...
    Series series Biomedical and Life Sciences (R0)
    This book offers a broad overview of the concepts and research findings in immunometabolism. The immune system is made up of numerous different cell types, pathways, and components that must be able to respond rapidly to a pathogen or cancer, but must also remain quiescent in the absence of challenges. Immune cells rely on metabolic pathways to adapt to changing environments and stimuli. ... Read more

    $141.99 CAD