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Showing 1 - 12 of 34 results for “raimund mannhold”
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  • RNA as a Drug Target

    The Next Frontier for Medicinal Chemistry

    by Raimund Mannhold, Helmut Buschmann, Jörg Holenz ...
    Series series Methods & Principles in Medicinal Chemistry
    Discover a new paradigm in drug discovery that greatly expands the space of addressable drug targets and potential novel drugsExisting paradigms for drug discovery have focused largely on enzymes and other proteins as drug targets. In recent years, however, different varieties of ribonucleic acids have emerged as a viable focus for target-based drug discovery, with the potential to revolutionize ... Read more

    $194.99 CAD

  • Open Access Databases and Datasets for Drug Discovery

    by Raimund Mannhold, Helmut Buschmann, Jörg Holenz ...
    Series series Methods & Principles in Medicinal Chemistry
    Open Access Databases and Datasets for Drug DiscoveryTimely resource discussing the future of data-driven drug discovery and the growing number of open-source databasesWith an overview of 90 freely accessible databases and datasets on all aspects of drug design, development, and discovery, Open Access Databases and Datasets for Drug Discovery is a comprehensive guide to the vast amount of “free ... Read more

    $194.99 CAD

  • Flow and Microreactor Technology in Medicinal Chemistry

    by Raimund Mannhold, Helmut Buschmann, Jörg Holenz, Esther Alza ...
    Series series Methods & Principles in Medicinal Chemistry
    Learn to master a powerful technology to enable a faster drug discovery workflowThe ultimate dream for medicinal chemists is the ability to synthesize new drug-like compounds with the push of a button. The key to synthesizing chemical compounds more quickly and accurately lies in computer-controlled technologies that can be optimized by machine learning. Recent developments in computer-controlled ... Read more

    $170.99 CAD

  • Targeted Drug Delivery

    by Raimund Mannhold, Helmut Buschmann, Yogeshwar Bachhav, Jörg Holenz ...
    Series series Methods & Principles in Medicinal Chemistry
    Targeted Drug DeliveryNovel approaches in targeted drug delivery for both small molecule and biopharmaceutical drugsTargeted Drug Delivery explores a new frontier in drug research that has become a focus for developing novel medications. The work discusses a wide range of approaches for targeting small molecules as well as peptide and macromolecular drugs, from prodrugs to drug conjugates to drug ... Read more

    $194.99 CAD

  • Neglected Tropical Diseases

    Drug Discovery and Development

    by Raimund Mannhold, Helmut Buschmann, Jörg Holenz ...
    Series series Methods & Principles in Medicinal Chemistry
    A drug discovery reference to the crippling tropical diseases that affect more than 1 billion people.Neglected Tropical Diseases is the first book of its kind to offer a guide that follows the World Health Organization?s list of neglected tropical diseases. The authors?all are experts on the topic?address the development of effective treatments for 12 crippling infectious diseases that affect ... Read more

    $199.99 CAD

  • Innovative Dosage Forms

    Design and Development at Early Stage

    by Raimund Mannhold, Helmut Buschmann, Jörg Holenz ...
    Series series Methods & Principles in Medicinal Chemistry
    Teaches future and current drug developers the latest innovations in drug formulation design and optimizationThis highly accessible, practice-oriented book examines current approaches in the development of drug formulations for preclinical and clinical studies, including the use of functional excipients to enhance solubility and stability. It covers oral, intravenous, topical, and parenteral ... Read more

    $187.99 CAD

  • Target Discovery and Validation

    Methods and Strategies for Drug Discovery

    by Raimund Mannhold, Helmut Buschmann, Jörg Holenz ...
    Series series Methods & Principles in Medicinal Chemistry
    The modern drug developers? guide for making informed choices among the diverse target identification methodsTarget Discovery and Validation: Methods and Strategies for Drug Discovery offers a hands-on review of the modern technologies for drug target identification and validation. With contributions from noted industry and academic experts, the book addresses the most recent chemical, biological, ... Read more

    $206.99 CAD

  • Early Drug Development

    Bringing a Preclinical Candidate to the Clinic

    by Raimund Mannhold, Helmut Buschmann, Jörg Holenz ...
    Series series Methods & Principles in Medicinal Chemistry
    This one-stop reference systematically covers key aspects in early drug development that are directly relevant to the discovery phase and are required for first-in-human studies.Its broad scope brings together critical knowledge from many disciplines, ranging from process technology to pharmacology to intellectual property issues.After introducing the overall early development workflow, the ... Read more

    $348.99 CAD

  • Transporters as Drug Targets

    by Raimund Mannhold, Gerd Folkers, Helmut Buschmann ...
    Series series Methods & Principles in Medicinal Chemistry
    As opposed to other books on the topic, this volume is unique in also covering emerging transporter targets.Following a general introduction to the importance of targeting transporter proteins with drugs, the book systematically presents individual transporter classes and explains their pharmacology and physiology. The text covers all transporter families with known or suspected importance as drug ... Read more

    $184.99 CAD

  • Epigenetic Drug Discovery

    by Raimund Mannhold, Helmut Buschmann, Jörg Holenz ...
    Series series Methods & Principles in Medicinal Chemistry
    This broad view of epigenetic approaches in drug discovery combines methods and strategies with individual targets, including new and largely unexplored ones such as sirtuins and methyl-lysine reader proteins.Presented in three parts - Introduction to Epigenetics, General Aspects and Methodologies, and Epigenetic Target Classes - it covers everything any drug researcher would need in order to know ... Read more

    $223.99 CAD

  • Protein Therapeutics

    by Raimund Mannhold, Gerd Folkers, Helmut Buschmann ...
    Series series Methods & Principles in Medicinal Chemistry
    In this practice-oriented two volume handbook, professionals from some of the largest biopharmaceutical companies and top academic researchers address the key concepts and challenges in the development of protein pharmaceuticals for medicinal chemists and drug developers of all trades.Following an introduction tracing the rapid development of the protein therapeutics market over the last decade, ... Read more

    $338.99 CAD

  • Fragment-based Drug Discovery

    Lessons and Outlook

    by Raimund Mannhold, Hugo Kubinyi, Gerd Folkers ...
    Series series Methods & Principles in Medicinal Chemistry
    From its origins as a niche technique more than 15 years ago, fragment-based approaches have become a major tool for drug and ligand discovery, often yielding results where other methods have failed. Written by the pioneers in the field, this book provides a comprehensive overview of current methods and applications of fragment-based discovery, as well as an outlook on where the field is headed ... Read more

    $206.99 CAD