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  • Iron Uptake in Bacteria with Emphasis on E. coli and Pseudomonas

    Series series Chemistry and Material Science (R0)
    Iron is essential for the growth of most bacteria because it serves as a cofactor for vital enzymes and for the components of the electron transport chain. Moreover, Iron plays an important role in bacterial pathogenicity; in fact, the iron transport systems in bacteria works as target for designing novel antibiotics. Because iron is not soluble under aerobic conditions, bacteria have had to find ... Read more

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    In 1898, an Austrian microbiologist Heinrich Winterberg made a curious observation: the number of microbial cells in his samples did not match the number of colonies formed on nutrient media (Winterberg 1898). About a decade later, J. Amann qu- tified this mismatch, which turned out to be surprisingly large, with non-growing cells outnumbering the cultivable ones almost 150 times (Amann 1911). ... Read more

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  • Reprogramming Microbial Metabolic Pathways

    Series series Biomedical and Life Sciences (R0)
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    Series series Biomedical and Life Sciences (R0)
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    Over the past century, the majority of chemical and energy needs of our industrial society has originated from fossilized carbon sources (coal, crude oil, natural gas). Increasingly, there is a realization that utilization of the fossilized carbon sources has adverse environmental consequences in the form of increasing concentration of greenhouse gases. We are also becoming aware of the limited ... Read more

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