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Showing 1 - 12 of 12 results for “moshe elkabets”
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  • Resistance to Anti-Cancer Therapeutics Targeting Receptor Tyrosine Kinases and Downstream Pathways

    Edited by Yosef Yarden, Moshe Elkabets ...
    Series series Biomedical and Life Sciences (R0)
    This volume comprehensively covers the multiplicity and diversity of mechanisms underlying patient resistance to currently approved anti-cancer drugs, including tyrosine kinase inhibitors and monoclonal antibodies, blockers of growth factor receptors and their downstream pathways, which play essential functions in cancer progression. Each chapter will cover a specific group of targets and the ... Read more

    $179.99 CAD

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  • Targeting Protein Kinases for Cancer Therapy

    by David J. Matthews, Mary E. Gerritsen ...
    An expert guide to targeting protein kinases in cancer therapyResearch has shown that protein kinases can instigate the formation and spread of cancer when they transmit faulty signals inside cells. Because of this fact, pharmaceutical scientists have targeted kinases for intensive study, and have been working to develop medicinal roadblocks to sever their malignant means of communication.Complete ... Read more

    $191.99 CAD

  • Resistance of Cancer Cells to CTL-Mediated Immunotherapy

    Edited by Benjamin Bonavida, Salem Chouaib ...
    Series series Biomedical and Life Sciences (R0)
    This comprehensive volume explores the latest research on the mechanisms of resistance in cancer cells to CTL-mediated immunotherapy. Chapter topics discuss cell-mediated immunity as the result of cytotoxic T-lymphocytes (CTL) directed specifically against cancer cells. In addition, the volume reviews how CTL mediate the cytotoxic activity, in large part, by the indication of apoptosis; hence, ... Read more

    $115.99 CAD

  • Anticancer Drug Development

    Edited by Bruce C. Baguley, David J. Kerr ...
    Here in a single source is a complete spectrum of ideas on the development of new anticancer drugs. Containing concise reviews of multidisciplinary fields of research, this book offers a wealth of ideas on current and future molecular targets for drug design, including signal transduction, the cell division cycle, and programmed cell death. Detailed descriptions of sources for new drugs and ... Read more

    $159.99 CAD

  • Myelodysplastic Syndromes

    by H. Joachim Deeg, David T. Bowen, Steven D. Gore, Torsten Haferlach, Michelle M. Le Beau, Charlotte Niemeyer ...
    Series series Medicine (R0)
    The diagnosis of myelodysplastic syndromes (MDS), a heterogeneous group of clonal hematopoietic disorders, is being made with increasing frequency over the past decade owing to increased recognition, improved understanding, and an aging population. This book, completely updated since the first edition, summarizes in a concise and focused way the current knowledge of all aspects of MDS. Clinical ... Read more

    $128.99 CAD

  • Cancer Stem Cells

    by Vinagolu K. Rajasekhar ...
    Cancer Stem Cells covers a wide range of topics in cancer stem cell biology, including the functional characteristics of cancer stem cells and how they're generated, where they are localized, the means by which cancer stem cells can be targeted, and how cancer stem cells can be reprogrammed back to normal tissue stem cells. Each chapter begins with a brief historical note and concept summary, ... Read more

    $157.99 CAD

  • Translational Research in Breast Cancer

    Biomarker Diagnosis, Targeted Therapies and Approaches to Precision Medicine

    Edited by Erwei Song, Hai Hu ...
    Series series Biomedical and Life Sciences (R0)
    This book offers a comprehensive introduction to translational efforts in breast cancer, addressing the latest approaches to precision medicine based on the current state of understanding of breast cancer.With the latest developments in breast cancer research, our understanding of the genomic changes and the oncogenic signaling cascade of breast cancer has made considerable strides. Further, the ... Read more

    $256.99 CAD

  • Melanoma Development

    Molecular Biology, Genetics and Clinical Application

    Edited by Anja K. Bosserhoff ...
    Series series Biomedical and Life Sciences (R0)
    This book focuses on malignant melanoma, discussing the current state of scientific knowledge and providing insights into the underlying basic mechanisms, the molecular changes, genetics and genomics.Human Melanoma is a dangerous type of skin cancer affecting an increasing population, and a better understanding of its development will help in finding sophisticated targeted therapies.The second ... Read more

    $205.99 CAD

  • Therapeutic Kinase Inhibitors

    Edited by Ingo K. Mellinghoff, Charles L. Sawyers ...
    Series series Biomedical and Life Sciences (R0)
    Cancer drug development is currently undergoing a profound shift. Drugs targeting fundamental cellular processes such DNA-replication and microtubule function, often referred to as “chemotherapy” and still the backbone of most cancer treatment regimens, are increasingly being complemented by or replaced with kinase inhibitors. This new class of drugs targets enzymes which provide growth and ... Read more

    $179.99 CAD

  • Emerging Concepts Targeting Immune Checkpoints in Cancer and Autoimmunity

    Edited by Akihiko Yoshimura ...
    Series series Biomedical and Life Sciences (R0)
    This volume reviews the current state of research on immune checkpoints and offers novel concepts. It discusses the two most important immune checkpoints: T lymphocyte-associated antigen-4 (CTLA-4) and programmed cell death-1 (PD-1). It shows that antagonistic antibodies against these two molecules are highly effective in the treatment of various cancers and that PD-1 and CTLA-4 have been linked ... Read more

    $218.99 CAD

  • Targeted Therapy of Acute Myeloid Leukemia

    Edited by Michael Andreeff ...
    Series series Medicine (R0)
    This book provides an unprecedented overview of "Targeted Therapies" for acute myeloid leukemias. It aims at an almost comprehensive coverage of the diverse therapeutic strategies that have been developed during the last decade and are now being evaluated in early clinical trials. Paired and authoritative chapters by leading research scientists and clinicians explain basic concepts and clinical ... Read more

    $179.99 CAD

  • Antiangiogenic Drugs as Chemosensitizers in Cancer Therapy

    by Lucia Morbidelli ...
    Series Book 18 - Cancer Sensitizing Agents for Chemotherapy
    Anti-angiogenic Drugs as Chemosensitizers in Cancer Therapy, Volume 19 focuses on the use of anti-angiogenic drugs as sensitizers of tumor cells to the inhibitory activity of antitumor agents. Conventional and novel anti-neoplastic agents (cytotoxic molecules, hormones/antihormones, immunotherapies) are taken into consideration, along with advances made in combination therapies. The book ... Read more

    $155.19 CAD