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Showing 1 - 12 of 12 results for “mary e spilker”
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  • Quantitative Systems Pharmacology

    Edited by Erica L. Bradshaw, Mary E. Spilker ...
    Series series Biomedical and Life Sciences (R0)
    Quantitative Systems Pharmacology as a discipline has matured over the past decade and is being used more frequently in academia and industry; however, dedicated training programs and courses are limited. This book will provide a go-to educational reference for a broad audience with topics including: the technology’s history, comparisons to other modeling methods and emerging opportunities to ... Read more

    $205.99 CAD

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  • Early Drug Development

    Strategies and Routes to First-in-Human Trials

    Edited by Mitchell N. Cayen ...
    The focus of early drug development has been the submission of an Investigational New Drug application to regulatory agencies. Early Drug Development: Strategies and Routes to First-in-Human Trials guides drug development organizations in preparing and submitting an Investigational New Drug (IND) application. By explaining the nuts and bolts of preclinical development activities and their ... Read more

    $215.99 CAD

  • Network Medicine

    Complex Systems in Human Disease and Therapeutics

    by Elliott M. Antman, Michael A. Calderwood, Benoit Charloteaux, Clary B. Clish, Michael E. Cusick, Dawn Lisa Demeo, John C. Earls, James A. Eddy, Samik Ghosh, Kimberly R. Glass, Jeremy Gunawardena, David E. Hill, Isabelle Huvent, Hiroaki Kitano, Isabelle Landrieu, Jessica Lasky-Su, Arnaud Leroy, Guy Lippens, Augusto A. Litonjua, Douglas Luke, Shuyi Ma, Calum A. MacRae, Jörg Menche, Sucheendra K. Palaniappan, Benjamin Parent, Sudhakaran Prabakaran, Nathan Price, John Quackenbush, Thomas Rolland, Martin W. Schoen, Caroline Smet-Nocca, Joanne E. Sordillo, Marc Vidal, George M. Weinstock, Scott Tillman Weiss ...
    Big data, genomics, and quantitative approaches to network-based analysis are combining to advance the frontiers of medicine as never before. Network Medicine introduces this rapidly evolving field of medical research, which promises to revolutionize the diagnosis and treatment of human diseases. With contributions from leading experts that highlight the necessity of a team-based approach in ... Read more

    $66.99 CAD

  • Proteomic and Metabolomic Approaches to Biomarker Discovery

    Edited by Haleem J. Issaq ...
    Proteomic and Metabolomic Approaches to Biomarker Discovery demonstrates how to leverage biomarkers to improve accuracy and reduce errors in research. Disease biomarker discovery is one of the most vibrant and important areas of research today, as the identification of reliable biomarkers has an enormous impact on disease diagnosis, selection of treatment regimens, and therapeutic monitoring. ... Read more

    $131.99 CAD

  • Metabolomics Perspectives

    From Theory to Practical Application

    Edited by Jacopo Troisi ...
    Metabolomics Perspectives: From Theory to Practical Application is an expertly written volume, which provides a thorough description of the current state-of-the-art in the metabolomics field. The philosophy behind the book is to guide the reader in a step-by-step exploration of metabolomics experiments, ranging from sample preparation to data extraction, analysis and interpretation, and to discuss ... Read more

    $155.99 CAD

  • Physiologically Based Pharmacokinetic (PBPK) Modeling and Simulations

    Principles, Methods, and Applications in the Pharmaceutical Industry

    by Sheila Annie Peters ...
    Physiologically Based Pharmacokinetic (PBPK) Modeling and SimulationsThe first book dedicated to the emerging field of physiologically based pharmacokinetic modeling (PBPK)Now in its second edition, Physiologically Based Pharmacokinetic (PBPK) Modelling and Simulations: Principles, Methods, and Applications in the Pharma Industry remains the premier reference book throughout the rapidly growing ... Read more

    $207.99 CAD

  • Protein Families

    Relating Protein Sequence, Structure, and Function

    by Vladimir Uversky ...
    Series series Wiley Series in Protein and Peptide Science
    New insights into the evolution and nature of proteinsExploring several distinct approaches, this book describes the methods for comparing protein sequences and protein structures in order to identify homologous relationships and classify proteins and protein domains into evolutionary families. Readers will discover the common features as well as the key philosophical differences underlying the ... Read more

    $173.99 CAD

  • Modern CNS Drug Discovery

    Reinventing the Treatment of Psychiatric and Neurological Disorders

    Edited by Rudy Schreiber ...
    Series series Biomedical and Life Sciences (R0)
    This textbook provides a comprehensive overview of the currently used concepts, approaches and technologies in the discovery and development of new treatments for the full spectrum of disorders of the central nervous system. It guides the reader through all essential steps, from finding an innovative idea, to the registration of a new drug.Divided into four sections, the book starts by presenting ... Read more

    $70.99 CAD

  • Systems Biology in Drug Discovery and Development

    by Daniel L. Young, Seth Michelson ...
    Series Book 9 - Wiley Series on Technologies for the Pharmaceutical Industry
    The first book to focus on comprehensive systems biology as applied to drug discovery and developmentDrawing on real-life examples, Systems Biology in Drug Discovery and Development presents practical applications of systems biology to the multiple phases of drug discovery and development. This book explains how the integration of knowledge from multiple sources, and the models that best represent ... Read more

    $151.99 CAD

  • Big Data in Radiation Oncology

    Edited by Jun Deng, Lei Xing ...
    Series series Imaging in Medical Diagnosis and Therapy
    Big Data in Radiation Oncology gives readers an in-depth look into how big data is having an impact on the clinical care of cancer patients. While basic principles and key analytical and processing techniques are introduced in the early chapters, the rest of the book turns to clinical applications, in particular for cancer registries, informatics, radiomics, radiogenomics, patient safety and ... Read more

    $119.99 CAD

  • Computational Toxicology

    Risk Assessment for Chemicals

    Edited by Sean Ekins ...
    Series series Wiley Series on Technologies for the Pharmaceutical Industry
    A key resource for toxicologists across a broad spectrum of fields, this book offers a comprehensive analysis of molecular modelling approaches and strategies applied to risk assessment for pharmaceutical and environmental chemicals.Provides a perspective of what is currently achievable with computational toxicology and a view to future developmentsHelps readers overcome questions of data sources, ... Read more

    $211.99 CAD

  • Systems Biology in Biotech & Pharma

    A Changing Paradigm

    by Seth Michelson, Aleš Prokop ...
    Series series Medicine (R0)
    The US is currently well ahead of the rest of the world in the development and application of SB and its principles especially as they pertain to basic medical research and development. This lead is largely due to its earlier start in the academic arena. However, there is evidence of rapid development in both the UK/EU and Japan, and the gap is narrowing, particularly in the UK. From an industrial ... Read more

    $64.99 CAD