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Showing 1 - 12 of 12 results for “jacinta serpa”
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  • Cancer Metabolic Remodeling

    New Avenues for Metabolism-based Therapy

    Edited by Jacinta Serpa, Cindy Mendes ...
    Series series Biomedical and Life Sciences (R0)
    This book offers readers a comprehensive exploration of the critical role that metabolic remodeling plays in cancer cell survival and progression. Faced with persistent stress, such as nutrient deprivation, hypoxia, and immune pressure, cancer cells rely on the tumor microenvironment (TME) as a key driver of metabolic adaptation.This edited volume presents a multidisciplinary view of cancer ... Read more

    $281.99 CAD

  • Tumor Microenvironment

    The Main Driver of Metabolic Adaptation

    Edited by Jacinta Serpa ...
    Series series Biomedical and Life Sciences (R0)
    The way a cell undergoes malignant transformation should meet their capacity of surviving in the microenvironment of the organ where the cancer will develop. Metabolic adaptation is for sure one of the criteria that must be accomplished, driven by metabolic plasticity that allows the adaptation of cancer cells to the availability of energy and biomass sources that will sustain cell survival and ... Read more

    $192.99 CAD

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  • Handbook of Cell Signaling

    Edited by Ralph A. Bradshaw, Edward A. Dennis ...
    Series series Cell Biology
    Handbook of Cell Signaling, Three-Volume Set, 2e, is a comprehensive work covering all aspects of intracellular signal processing, including extra/intracellular membrane receptors, signal transduction, gene expression/translation, and cellular/organotypic signal responses. The second edition is an up-to-date, expanded reference with each section edited by a recognized expert in the field. Tabular ... Read more

    $472.99 CAD

  • Pharmacogenomics of Human Drug Transporters

    Clinical Impacts

    by Toshihisa Ishikawa, Richard B. Kim, Jörg König ...
    Sets the foundation for safer, more effective drug therapiesWith this book as their guide, readers will discover how to apply our current understanding of the pharmacogenomics of drug transporters to advance their own drug discovery and development efforts. In particular, the book explains how new findings in the field now enable researchers to more accurately predict drug interactions and adverse ... Read more

    $191.99 CAD

  • Cytochrome P450 2D6

    Structure, Function, Regulation and Polymorphism

    by Shufeng Zhou ...
    Cytochromes are proteinsthat catalyze electron transfer reactions of well-known metabolic pathways and are classified in various superfamilies. The CYP, or P450, superfamily accounts for 90% of the oxidative metabolism of clinical drugs. One member of this superfamily, P450 2D6 (or CYP2D6), singlehandedly metabolizes about 25% of all medications in the human liver. Cytochrome P450 2D6: Structure, ... Read more

    $100.99 CAD

  • Resistance of Cancer Cells to CTL-Mediated Immunotherapy

    Edited by Benjamin Bonavida, Salem Chouaib ...
    Series series Biomedical and Life Sciences (R0)
    This comprehensive volume explores the latest research on the mechanisms of resistance in cancer cells to CTL-mediated immunotherapy. Chapter topics discuss cell-mediated immunity as the result of cytotoxic T-lymphocytes (CTL) directed specifically against cancer cells. In addition, the volume reviews how CTL mediate the cytotoxic activity, in large part, by the indication of apoptosis; hence, ... Read more

    $115.99 CAD

  • MicroRNA in Regenerative Medicine

    Edited by Chandan K. Sen ...
    Regulating virtually all biological processes, the genome's 2,654 newly discovered variants of mature microRNAs – short ribonucleic acid molecules found in eukaryotic cells – hold a key role in the body's toolkit of regenerative and reparative capacities. Identifying how to activate and deliver these specialist molecules may aid in the repair and regeneration of major tissue and organ damage in ... Read more

    $309.99 CAD

  • Glioblastoma Resistance to Chemotherapy: Molecular Mechanisms and Innovative Reversal Strategies

    Edited by Ramasamy Paulmurugan, Tarik F. Massoud ...
    Series Book 15 - Cancer Sensitizing Agents for Chemotherapy
    Glioblastoma Resistance to Chemotherapy: Molecular Mechanisms and Innovative Reversal Strategies brings current knowledge from an international team of experts on the science and clinical management of glioblastoma chemoresistance. The book discusses topics such as molecular mechanisms of chemoresistance, experimental models to study chemoresistance, chemoresistance to drugs other than ... Read more

    $155.99 CAD

  • Trends in Stem Cell Proliferation and Cancer Research

    Edited by Rodrigo R. Resende, Henning Ulrich ...
    Series series Biomedical and Life Sciences (R0)
    The book will discuss the molecular mechanisms of cancer diseases, stem cell proliferation and transformation into cancer cells beyond the physiological processes that occur in normal stem cell biology. Some of the key oncogenic events in cancer and their signaling pathways that regulate cell division cycle progression will be described considering prospects for using such knowledge in advanced ... Read more

    $256.99 CAD

  • Targets of Cancer Diagnosis and Treatment

    Ion Transport in Tumor Biology

    Edited by Christian Stock, Luis A. Pardo ...
    Series series Biomedical and Life Sciences (R0)
    This third and final volume in the "Ion Transport in Tumor Biology" collection presents novel diagnostic and therapeutic approaches in cancer based on the exploitation of ion transport proteins. The authors critically examine several transportome members, particularly Na+, K+, Ca2+, and Cl- channels, as well as organic solute carriers regarding their suitability as therapeutic targets. Synergistic ... Read more

    $167.99 CAD

  • Mitochondrial Biology and Experimental Therapeutics

    Edited by Paulo J. Oliveira ...
    This book addresses the therapeutic strategies to target mitochondrial metabolism in diseases where the function of that organelle is compromised, and it discusses the effective strategies used to create mitochondrial-targeted agents that can become commercially available drug delivery platforms. The consistent growth of research focused in understanding the multifaceted role of mitochondria in ... Read more

    $218.99 CAD

  • Apoptosome

    An up-and-coming therapeutical tool

    Edited by Francesco Cecconi, Marcello D'Amelio ...
    Series series Biomedical and Life Sciences (R0)
    "Apoptosome" is the first book that presents a concise synthesis of recent developments in the understanding of how the activation of the cell death cascade is handled by a cytosolic signalling platform known as the apoptosome.The book also discusses how insights into the regulation of apoptosome may be exploited for designing new drugs aimed at interfere with a plethora of pathogenetic processes ... Read more

    $179.99 CAD