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Showing 1 - 12 of 12 results for “hansheng wang”
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  • Sample Size Calculations in Clinical Research

    by Shein-Chung Chow, Jun Shao, Hansheng Wang, Yuliya Lokhnygina ...
    Series series Chapman & Hall/CRC Biostatistics Series
    Praise for the Second Edition:"… this is a useful, comprehensive compendium of almost every possible sample size formula. The strong organization and carefully defined formulae will aid any researcher designing a study." -Biometrics"This impressive book contains formulae for computing sample size in a wide range of settings. One-sample studies and two-sample comparisons for quantitative, binary, ... Read more

    $88.99 CAD

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  • Nonclinical Statistics for Pharmaceutical and Biotechnology Industries

    by Max Kuhn, Ian Peers, Stan Altan ...
    Series series Mathematics and Statistics (R0)
    This book serves as a reference text for regulatory, industry and academic statisticians and also a handy manual for entry level Statisticians. Additionally it aims to stimulate academic interest in the field of Nonclinical Statistics and promote this as an important discipline in its own right. This text brings together for the first time in a single volume a comprehensive survey of methods ... Read more

    $205.99 CAD

  • Introduction to Population Pharmacokinetic / Pharmacodynamic Analysis with Nonlinear Mixed Effects Models

    by Joel S. Owen, Jill Fiedler-Kelly ...
    This book provides a user-friendly, hands-on introduction to the Nonlinear Mixed Effects Modeling (NONMEM) system, the most powerful tool for pharmacokinetic / pharmacodynamic analysis.• Introduces requisite background to using Nonlinear Mixed Effects Modeling (NONMEM), covering data requirements, model building and evaluation, and quality control aspects• Provides examples of nonlinear modeling ... Read more

    $136.99 CAD

  • Bayesian Designs for Phase I-II Clinical Trials

    by Ying Yuan, Hoang Q. Nguyen, Peter F. Thall ...
    Series series Chapman & Hall/CRC Biostatistics Series
    Reliably optimizing a new treatment in humans is a critical first step in clinical evaluation since choosing a suboptimal dose or schedule may lead to failure in later trials. At the same time, if promising preclinical results do not translate into a real treatment advance, it is important to determine this quickly and terminate the clinical evaluation process to avoid wasting resources.Bayesian ... Read more

    $91.99 CAD

  • Benefit-Risk Assessment Methods in Medical Product Development

    Bridging Qualitative and Quantitative Assessments

    Edited by Qi Jiang, Weili He ...
    Series series Chapman & Hall/CRC Biostatistics Series
    Guides You on the Development and Implementation of B–R EvaluationsBenefit–Risk Assessment Methods in Medical Product Development: Bridging Qualitative and Quantitative Assessments provides general guidance and case studies to aid practitioners in selecting specific benefit–risk (B–R) frameworks and quantitative methods. Leading experts from industry, regulatory agencies, and academia present ... Read more

    $102.99 CAD

  • Practical Considerations for Adaptive Trial Design and Implementation

    Edited by Weili He, Olga M. Kuznetsova, José Pinheiro ...
    Series series Mathematics and Statistics (R0)
    This edited volume is a definitive text on adaptive clinical trial designs from creation and customization to utilization. As this book covers the full spectrum of topics involved in the adaptive designs arena, it will serve as a valuable reference for researchers working in industry, government and academia. The target audience is anyone involved in the planning and execution of clinical trials, ... Read more

    $205.99 CAD

  • Repeated Measures Design with Generalized Linear Mixed Models for Randomized Controlled Trials

    by Toshiro Tango ...
    Series series Chapman & Hall/CRC Biostatistics Series
    Repeated Measures Design with Generalized Linear Mixed Models for Randomized Controlled Trials is the first book focused on the application of generalized linear mixed models and its related models in the statistical design and analysis of repeated measures from randomized controlled trials. The author introduces a new repeated measures design called S:T design combined with mixed models as a ... Read more

    $91.99 CAD

  • Quick Guide to Good Clinical Practice

    How to Meet International Quality Standard in Clinical Research

    by Cemal Cingi, Nuray Bayar Muluk ...
    Series series Medicine (R0)
    This brand-new book offers a reference guide to understanding and applying the rules for properly conducting clinical trials to meet the international quality standard – Good Clinical Practice – provided by the International Conference on Harmonization (ICH).The work offers an updated perspective on the clinical research landscape within the context of the clinical trial regulatory frameworks in ... Read more

    $115.99 CAD

  • Handbook of Methods for Designing, Monitoring, and Analyzing Dose-Finding Trials

    Edited by John O'Quigley, Alexia Iasonos, Björn Bornkamp ...
    Series series Chapman & Hall/CRC Handbooks of Modern Statistical Methods
    Handbook of Methods for Designing, Monitoring, and Analyzing Dose-Finding Trials gives a thorough presentation of state-of-the-art methods for early phase clinical trials. The methodology of clinical trials has advanced greatly over the last 20 years and, arguably, nowhere greater than that of early phase studies. The need to accelerate drug development in a rapidly evolving context of targeted ... Read more

    $156.99 CAD

  • Clinical Trial Optimization Using R

    Edited by Alex Dmitrienko, Erik Pulkstenis ...
    Series series Chapman & Hall/CRC Biostatistics Series
    Clinical Trial Optimization Using R explores a unified and broadly applicable framework for optimizing decision making and strategy selection in clinical development, through a series of examples and case studies. It provides the clinical researcher with a powerful evaluation paradigm, as well as supportive R tools, to evaluate and select among simultaneous competing designs or analysis options. ... Read more

    $102.99 CAD

  • An Introduction to Statistics with Python

    With Applications in the Life Sciences

    by Thomas Haslwanter ...
    Series series Mathematics and Statistics (R0)
    This textbook provides an introduction to the free software Python and its use for statistical data analysis. It covers common statistical tests for continuous, discrete and categorical data, as well as linear regression analysis and topics from survival analysis and Bayesian statistics. Working code and data for Python solutions for each test, together with easy-to-follow Python examples, can be ... Read more

    $64.99 CAD

  • Statistical Methods in Toxicology

    Proceedings of a Workshop during EUROTOX ’90 Leipzig, Germany, September 12–14, 1990

    Edited by Ludwig Hothorn ...
    Series Book 43 - Lecture Notes in Medical Informatics
    This book contains selected papers from a workshop on modern statistical methods in toxicology held during the EUROTOX '90 conference in Leipzig. The papers deal with the biostatistical evaluation of the commonly used toxicological assays, i.e. mutagenicity, long-term carcinogenicity, embryotoxicity and chronic toxicity assays. The biological background is considered in detail, and most of the ... Read more

    $115.99 CAD