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  • Antibody Fc

    Linking Adaptive and Innate Immunity

    Antibody Fc is the first single text to synthesize the literature on the mechanisms underlying the dramatic variability of antibodies to influence the immune response. The book demonstrates the importance of the Fc domain, including protective mechanisms, effector cell types, genetic data, and variability in Fc domain function. This volume is a critical single-source reference for researchers in ... Read more

    $176.79 CAD

  • Fc Mediated Activity of Antibodies

    Structural and Functional Diversity

    Series series Biomedical and Life Sciences (R0)
    This volume explores several aspects of how antibodies mediate their activity in vivo, ranging from cancer immunotherapy to autoimmunity, infection, and vaccination. Divided into seven chapters, it provides in-depth insights into how antibodies and especially the antibody fragment crystallizable (Fc) domain modulate immune responses and antibody activity. The book begins by discussing evolutionary ... Read more

    $109.99 CAD

  • Fc Receptors

    Edited by Falk Nimmerjahn, Marc Daeron ...
    Series series Biomedical and Life Sciences (R0)
    This volume provides a state-of-the-art update on Fc Receptors (FcRs). It is divided into five parts. Part I, Old and New FcRs, deals with the long-sought-after FcµR and the recently discovered FCRL family and TRIM21. Part II, FcR Signaling, presents a computational model of FcεRI signaling, novel calcium channels, and the lipid phosphatase SHIP1. Part III, FcR Biology, addresses major ... Read more

    $205.99 CAD

  • Molecular and Cellular Mechanisms of Antibody Activity

    Edited by Falk Nimmerjahn ...
    Series series Biomedical and Life Sciences (R0)
    This book focuses on the function of antibodies in vivo. Recent years have seen an exponential growth in knowledge about the molecular and cellular mechanisms of antibody activity. These new results dramatically changed our view of how antibodies function in vivo. The importance of this class of molecules is demonstrated by the heightened susceptibility to infections of humans and mice with an ... Read more

    $218.99 CAD

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    Series series Medicine (R0)
    Over the past decade, significant progress has been made in the theory and applications of pharmacodynamics of antimicrobial agents. On the basis of pharmacokinetic-pharmacodynamic modeling concepts it has become possible to describe and predict the time course of antimicrobial effects under normal and pathophysiological conditions. The study of pharmacokinetic-pharmacodynamic relationships can be ... Read more

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  • The Leishmaniases: Old Neglected Tropical Diseases

    Series series Biomedical and Life Sciences (R0)
    Out of the 20 neglected tropical diseases (NTDs) prioritized by the World Health Organization, the leishmaniases rank in the top 3 among those caused by protozoa. The purpose of this book is to provide the reader with a comprehensive and updated overview of all the aspects of leishmaniasis with a worldwide perspective – authors of many chapters include eminent scientists from both the Old and New ... Read more

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  • Hepatitis E Virus

    Edited by Youchun Wang ...
    Series series Biomedical and Life Sciences (R0)
    This book systematically and comprehensively discusses the biological, epidemiological and clinical characteristics of the hepatitis E virus (HEV). It presents current knowledge of HEV and explores experimental methods, treatment and prevention of HEV. First identified in the 1980s and cloned in 1990, HEV is the causative agent of Hepatitis E, which mainly occurs in developing regions, such as ... Read more

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  • Patho-Epigenetics of Disease

    Series series Biomedical and Life Sciences (R0)
    In multicellular organisms the establishment, maintenance, and programmed alterations of cell-type specific gene expression patterns are regulated by epigenetic mechanisms. Thus, epigenetic alterations (DNA methylation, DNA associated Polycomb-Trithorax protein complexes, histone modifications) ensure the unique transcriptional activity and phenotypic diversity of diploid cells that carry ... Read more

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  • The Vaccine Race

    Science, Politics, and the Human Costs of Defeating Disease

    **"A real jewel of science history...brims with suspense and now-forgotten catastrophe and intrigue...Wadman’s smooth prose calmly spins a surpassingly complicated story into a real tour de force."—The New York Times“Riveting . . . [The Vaccine Race] invites comparison with Rebecca Skloot's 2007 The Immortal Life of Henrietta Lacks.”—NatureThe epic and controversial story of a major breakthrough ... Read more

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  • Introduction to Molecular Medicine

    Series series Medicine (R0)
    How will increased understanding of the human genome affect our ability to diagnose and treat disease? The subject of recombinant DNA technology is no longer limited to the research laboratory; it is being discussed in ever-widening medical circles. Introduction to Molecular Medicine is especially written for the physician who is not a genetics expert but wishes to understand this new science and ... Read more

    $102.99 CAD

  • Bioterrorism and Infectious Agents

    A New Dilemma for the 21st Century

    Edited by I.W. Fong, Kenneth Alibek ...
    Series series Medicine (R0)
    Since the terrorist attack on the United States on September 11, 2001 and subsequent cases of anthrax in Florida and New York City, attention has been focused on the threat of b- logical warfare and bioterrorism. Biological warfare agents are de?ned as “living org- isms, whatever their nature, or infected material derived from them, which are used for h- tile purposes and intended to cause disease ... Read more

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  • BeadChip Molecular Immunohematology

    Toward Routine Donor and Patient Antigen Profiling by DNA Analysis

    Series series Springer Nature Proceedings excluding Computer Science
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