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  • Simple Mathematical Models of Gene Regulatory Dynamics

    Series series Mathematics and Statistics (R0)
    This is a short and self-contained introduction to the field of mathematical modeling of gene-networks in bacteria. As an entry point to the field, we focus on the analysis of simple gene-network dynamics. The notes commence with an introduction to the deterministic modeling of gene-networks, with extensive reference to applicable results coming from dynamical systems theory. The second part of ... Read more

    $64.99 CAD

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    Modeling Aspects of Urban Life

    by John A. Adam ...
    What mathematical modeling uncovers about life in the cityX and the City, a book of diverse and accessible math-based topics, uses basic modeling to explore a wide range of entertaining questions about urban life. How do you estimate the number of dental or doctor's offices, gas stations, restaurants, or movie theaters in a city of a given size? How can mathematics be used to maximize traffic flow ... Read more

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  • Basics of Bioinformatics

    Lecture Notes of the Graduate Summer School on Bioinformatics of China

    Series series Computer Science (R0)
    This book outlines 11 courses and 15 research topics in bioinformatics, based on curriculums and talks in a graduate summer school on bioinformatics that was held in Tsinghua University. The courses include: Basics for Bioinformatics, Basic Statistics for Bioinformatics, Topics in Computational Genomics, Statistical Methods in Bioinformatics, Algorithms in Computational Biology, Multivariate ... Read more

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  • Convergence of One-Parameter Operator Semigroups

    In Models of Mathematical Biology and Elsewhere

    Series Book 30 - New Mathematical Monographs
    This book presents a detailed and contemporary account of the classical theory of convergence of semigroups and its more recent development treating the case where the limit semigroup, in contrast to the approximating semigroups, acts merely on a subspace of the original Banach space (this is the case, for example, with singular perturbations). The author demonstrates the far-reaching applications ... Read more

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  • Gene Network Inference

    Verification of Methods for Systems Genetics Data

    Edited by Alberto Fuente ...
    Series series Biomedical and Life Sciences (R0)
    This book presents recent methods for Systems Genetics (SG) data analysis, applying them to a suite of simulated SG benchmark datasets. Each of the chapter authors received the same datasets to evaluate the performance of their method to better understand which algorithms are most useful for obtaining reliable models from SG datasets. The knowledge gained from this benchmarking study will ... Read more

    $179.99 CAD

  • The Physical Basis of Bacterial Quorum Communication

    Edited by Stephen J. Hagen ...
    Series series Physics and Astronomy (R0)
    Quorum sensing (QS) describes a chemical communication behavior that is nearly universal among bacteria. Individual cells release a diffusible small molecule (an autoinducer) into their environment. A high concentration of this autoinducer serves as a signal of high population density, triggering new patterns of gene expression throughout the population. However QS is often much more complex than ... Read more

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  • Biosimulation in Biomedical Research, Health Care and Drug Development

    Series series Biomedical and Life Sciences (R0)
    Biosimulation is an approach to biomedical research and the treatment of patients in which computer modeling goes hand in hand with experimental and clinical work. Constructed models are used to interpret experimental results and to accumulate information from experiment to experiment.This book explains the concepts used in the modeling of biological phenomena and goes on to present a series of ... Read more

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  • Dissecting Regulatory Interactions of RNA and Protein

    Combining Computation and High-throughput Experiments in Systems Biology

    by Marvin Jens ...
    Series series Engineering (R0)
    The work described in this book is an excellent example of interdisciplinary research in systems biology. It shows how concepts and approaches from the field of physics can be efficiently used to answer biological questions and reports on a novel methodology involving creative computer-based analyses of high-throughput biological data. Many of the findings described in the book, which are the ... Read more

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  • Modern Infectious Disease Epidemiology

    Concepts, Methods, Mathematical Models, and Public Health

    Series series Mathematics and Statistics (R0)
    Hardly a day goes by without news headlines concerning infectious disease threats. Currently the spectre of a pandemic of influenza A|H1N1 is raising its head, and heated debates are taking place about the pro’s and con’s of vaccinating young girls against human papilloma virus. For an evidence-based and responsible communication of infectious disease topics to avoid misunderstandings and ... Read more

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  • The Fundamentals of Modern Statistical Genetics

    Series series Mathematics and Statistics (R0)
    This book covers the statistical models and methods that are used to understand human genetics, following the historical and recent developments of human genetics. Starting with Mendel’s first experiments to genome-wide association studies, the book describes how genetic information can be incorporated into statistical models to discover disease genes. All commonly used approaches in statistical ... Read more

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  • Evolutionary Bioinformatics

    Series series Biomedical and Life Sciences (R0)
    Now in its third edition and supplemented with more online material, this book aims to make the "new" information-based (rather than gene-based) bioinformatics intelligible both to the "bio" people and the "info" people. Books on bioinformatics have traditionally served gene-hunters, and biologists who wish to construct family trees showing tidy lines of descent. While dealing extensively with the ... Read more

    $192.99 CAD

  • Mechanisms of Atrial Arrhythmias

    Insights from the Development of a Biophysically Detailed Model of the Human Atria

    Series series Physics and Astronomy (R0)
    This thesis describes the development of biophysically detailed computer models of the human atria and torso to study the underlying mechanisms of cardiac diseases, some of the most common causes of morbidity and mortality. This is a cross-disciplinary project, involving fundamentals of cardiac electrophysiology, physics of excitable media, applied mathematics and high performance scientific ... Read more

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