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  • Behavioral Neurobiology of Huntington's Disease and Parkinson's Disease

    Series series Biomedical and Life Sciences (R0)
    Motor dysfunction and cognitive impairment are major symptoms in both Huntington’s Disease (HD) and Parkinson’s Disease (PD). A breakthrough in HD research was the identification of the gene that causes this devastating monogenetic illness. Similarly, several genes were found to cause familial forms of PD. With their identification, a plethora of genetic animal models has been generated and has ... Read more

    $115.99 CAD

  • Recent Advances in Parkinsons Disease

    Part II: Translational and Clinical Research

    Series Book 184 - Progress in Brain Research
    This second volume follows on from Part I by reviewing the variety of animal models of PD current available (from drosophila to rodents to non-human primate species) and their specific contributions to PD research. This is followed by comprehensive coverage of functional neuroimaging studies that explore different pathophysiological questions and evaluate treatment outcome in PD patients. ... Read more

    $255.99 CAD

  • Recent Advances in Parkinsons Disease

    Part I: Basic Research

    Series Book 183 - Progress in Brain Research
    This first volume starts with an overview on current perspectives in genetic research and on the molecular mechanisms of neurodegeneration. This is followed by a selection of hot topics in pathophysiological research, from molecular studies to system-level investigations based on in vivo electrophysiological recordings and neurocomputational methods. - Complete overview of hot topics and ... Read more

    $255.99 CAD

  • Recent Advances in Parkinson's Disease

    Series Book 252 - Progress in Brain Research
    Recent Advances in Parkinson´s Disease Research, Volume 252, represents a follow-up on two previous volumes presented in the Progress in Brain Research series, Volumes 193 and 193, both published in 2010. It contains a collection of overview articles written by leading researchers in Parkinson's, discussing the most important advances made in basic, translational and clinical research. Topics of ... Read more

    $254.39 CAD

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    Series series Medicine (R0)
    This first volume in a projected series contains the proceedings of the first of the Keio University International Symposia for Life Sciences and Medicine under the sponsorship of the Keio University Medical Science Fund. As stated in the address by the President of Keio University at the opening of the 1996 symposium, the fund of Dr. Mitsunada Sakaguchi. The Keio was established by the generous ... Read more

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  • Trinucleotide Diseases and Instability

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    Series series Biomedical and Life Sciences (R0)
    Till recently, mutations in genes were described in textbooks as deletions or point mutations. These mutations can be inherited from a parent or they are de novo alterations. The discovery in 1991 that human disease can be caused by large-scale ex pansion of highly unstable trinucleotide repeats has elucidated a new mutation mechanism, heritable unstable DNA. In the subsequent years more then 10 ... Read more

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    Series series Biomedical and Life Sciences (R0)
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  • Müller Cells in the Healthy and Diseased Retina

    Series series Biomedical and Life Sciences (R0)
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  • Folding for the Synapse

    Series series Biomedical and Life Sciences (R0)
    Folding for the Synapse addresses the current view on how protein folding and misfolding, controlled by molecular chaperones, contribute to synapse function and dysfunction. Molecular chaperones have been studied in relation to de novo protein folding, but there is increasing awareness that chaperone function is required for the regulation of protein dynamics when functioning physiologically as an ... Read more

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  • Growth Hormone II

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    The studies described here were carried out in the Neuroregul ation Group, Department of Physiology, University of Leiden, the Netherlands. Over the last decade, this group, in close collaboration with the Department of Neurosurgery of the Academic Hospital of Leiden, has studied the development of the central nervous system from a neuroanatomical as well as a clinical perspective. During this ... Read more

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